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New Oral Anticoagulants Markets
Date:3/25/2013

adaxa: Bringing Potential Sea Change in AF 167
7.2.5.3 Dabigatran's First Year in the Market 168
7.3 Parenteral Anticoagulants 168
7.3.1 Pharmacology of Parenteral Anticoagulants 169
7.3.2 Adverse Effects of Parenteral Anticoagulants 169
7.3.3 Parenteral Thrombin Inhibitors 170
7.3.3.1 Parenteral Indirect Thrombin Inhibitors 170
7.3.3.2 Market for Unfractionated Heparin (UFH) 171
7.3.3.3 Market for Low Molecular Weight Heparin (LMWH) 172
7.3.3.4 Distribution of LMWH Sales per Indication 173
7.3.4 Global Market for Lovenox 173
7.3.4.1 Lovenox: The Broadest Label 174
7.3.5 Pentasaccharide Anticogulants 174
7.3.5.1 Fondaparinux (Arixtra) 175
7.3.5.2 Arixtra: A Missed Opportunity 176
7.3.6 Parenteral Direct Thrombin Inhibitors 176
7.3.6.1 Bivalirudin (Angiomax) 176
7.4 Market for Venous Thromboembolic Drugs 177
7.5 Market for Direct Thrombin Inhibitors 178
7.6 Comparisons of Market Opportunities for Anti-Thrombotic Agents 179
7.7 Global Market for Anticoagulants 180
7.7.1 Market Share of Anticoagulants by Type 181
7.8 U.S. Market for Anticoagulants 182
7.9 More Anticoagulants in Pipeline 183

8. Market for Antiplatelets 184
8.1 Overview of this Chapter 184
8.2 The Threatened Market of Plavix 185
8.2.1 Patent Loss of Plavix 186
8.2.2 Patent Loss of Plavix and Competitive Advantages for New Entrants 187
8.3 Market for Effient (Prasugrel) 187
8.3.1 Slow Uptake of Effient 188
8.4 Market for Pletal (Cilostazol) 189
8.5 Market for Activase (Alteplase) 190
8.6 Market for Aggrenox 191
8.7 Market for CardioAspirin 192
8.8 Market for Opalmon 192
8.9 Market for Integrilin (Eptifibatide) 193
8.10 Market for ReoPro (Abciximab) 194
8.11 Market for Brilinta 195
8.12 Market for Diagnostic Assays of Platelet Function 196
8.13 The Anti-Platelet Pipeline 196

9. Deals in Anti-Thrombotic Therapeutics Sector 198
9.1 Sanof
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