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New Oral Anticoagulants Markets
Date:3/25/2013

oagulants 66
Table 3.19: Pharmacokinetic Parameters after Five Days of 1.5 mg/kg SC Once
Daily Doses of Enoxaparin Sodium Using 100 mg/mL or 200 mg/mL Concentrations 73
Table 3.20: Pharmacokinetic Parameters of Fondaparinux and Other Anticoagulants
74
Table 3.21: Composition of 20,000 Anti-Xa IU/mL Innohep 74
Table 3.22: Comparison of Characteristics of AVE5026, Idrabiotaparinux,
Otamixaban and RB006 76
Table 4.1: Comparison of Top Five Antiplatelets 83
Table 4.2: Estimated Yearly Incidence of Bleeding with Antiplatelets 85
Table 4.3: Summary of Evidence for Antiplatelets 86
Table 4.4: Cost of Antiplatelets 86
Table 4.5: Information on Ticagrelor 91
Table 4.6: Product Information on Clopidogrel 93
Table 4.7: CURE Incidence of Bleeding Complications (% Patients) 94
Table 4.8: Incidence of Bleeding Event in COMMIT (% Patients) 95
Table 5.1: Influence of Anticoagulants on Routine Coagulation Assays 99
Table 5.2: Influence of Anticoagulants on Thrombophilia Assays 99
Table 6.1: ACC/AHS Recommendations for Antiplatelet Therapy in Patients with
NSTEMI or UA 119
Table 6.2: Dosing of LMWH, Fondaparinux and Bivalirudin in Patients with NSTEMI
or UA 120
Table 6.3: ACC/AHA Recommendations for Anticoagulants Therapy in Patients with
NSTEMI or UA 120
Table 6.4: Antiplatelet Therapy in Patients with STEMI 121
Table 6.5: Anticoagulants Therapy in Patients with STEMI Who Receive
Fibrinolytic Therapy 121
Table 6.6: Anticoagulants Therapy in Patients with STEMI Who Undergo Primary PCI
122
Table 6.7: ACCP Recommendations for Thromboprophylactic Strategy Based on Risk
for VTE 122
Table 6.8: Anticoagulants Treatments for VTE 123
Table 6.9: Projections of Crude Cardiovascular Disease Prevalence, 2010-2030 125
Table 6.10: Projected Direct Medical Costs for Cardiovascular Diseases,
2010-2030 125
Table 6.11: Hamilton Score 131
Table 6.12:
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