Navigation Links
New Market Research Report from BioTrends Provides Insight on How Rheumatologists are Utilizing Biologic Agents in the Treatment of Rheumatoid Arthritis
Date:12/14/2009

EXTON, Pa., Dec. 14 /PRNewswire/ -- BioTrends Research Group, Inc. released ChartTrends®: Biologics in Rheumatoid Arthritis, a syndicated publication offering comprehensive insight into the management of RA patients. The report is based on a comparison of self-reported treatment approaches (as reported by 208 Rheumatologists) with actual patient level data for over 1,000 RA patients who are currently being treated with biologic agents.

To be eligible for the audit, patients had to currently be treated with a biologic agent (UCB's Cimzia, Amgen/Wyeth's Enbrel, Abbott's Humira, Bristol Myers Squibb's Orencia , Centocor-Ortho Biotech's Remicade and Simponi, or Genentech's Rituxan). Each brand was represented by at least 98 patient charts and Rheumatologists were limited to one audit per brand. The aim of ChartTrends is to understand actual treatment algorithms for the biologic brands and to clearly understand the "patient types" being treated with these agents. The audit captured patient demographic variables, co-morbidities, concomitant medications (including DMARD dose and strategy), disease history from diagnosis, biologic initiation, dose titration, brand switching, current clinical status and results from the most recent laboratory and radiographic tests.

Among the audited patients, 30% had their disease classified as severe. 76% of the patients were female, average age was 54 and overall, patients had been followed by their current Rheumatologist for 54 months. The majority of patients are currently prescribed concomitant DMARD therapy, such as methotrexate, although the prevalence varied by brand. While Rheumatologists have reported a more aggressive use of biologic agents, this study confirms these reports by demonstrating that the time between original RA diagnosis and biologic initiation has decreased significantly over the past five years.

First line use was most common with Enbrel and Humira, while Rituxan and Orencia were more commonly later line choices. Despite an indication for use after DMARD failure, more than three quarters of the Orencia patients (n=155) were not started on the therapy until at least one TNF-alpha failure. The two new TNF-alpha treatments, UCB's Cimzia and Centocor Ortho-Biotech's Simponi, are drawing from both biologic naive and switch patients. These new products have significantly higher rates of prior authorization required compared to other biologic agents.

Physicians were also presented with three new agents currently under development for RA, Roche's Actemra, GSK's Arzerra and Pfizer's CP-690. Rheumatologists have greatest familiarity with Actemra, but expressed highest interest in CP-690. The newer TNF-alpha agents (Simponi and Cimzia) along with the alternate mechanism of action agents Orencia and Rituxan appear to be at greatest risk from new entrants into the RA biologic market.

About BioTrends Research Group, Inc.

BioTrends Research Group, Inc. (www.bio-trends.com) provides syndicated and custom market research to pharmaceutical manufacturers competing in clinically evolving, specialty pharmaceutical markets. For information on BioTrends publications and research capabilities, please contact us at (610) 363-3872 or www.bio-trends.com.

All company, brand, or product names contained in this document may be trademarks of their respective holders.


    Contact:
    Paul Callahan
    610-363-3872
    pcallahan@bio-trends.com

SOURCE BioTrends Research Group, Inc.


'/>"/>
SOURCE BioTrends Research Group, Inc.
Copyright©2009 PR Newswire.
All rights reserved

Related medicine technology :

1. Enteral Feeding Device Market To Generate More Than $700 Million in the US & Europe by 2014
2. Drug Candidates in Pipeline Offer Potential for Parkinsons Disease Therapeutics Market, Says Frost & Sullivan
3. Reportlinker Adds Medical Fiber Optics - A World Market Analysis
4. Reportlinker Adds Bulk Paclitaxel - A Global Update of Market Trends & Opportunities
5. Reportlinker Adds US Home Healthcare Equipment & Services Market: An Analysis
6. Reportlinker Adds South Korean Market for Dental Implants and Final Abutments 2009
7. Reportlinker Adds European Markets for Drug Eluting and Bare Metal Stents 2009 (15 Countries)
8. Reportlinker Adds Prepackaged Medical Kits and Trays - A World Market Analysis
9. Reportlinker Adds Cardiac Biomarkers - A Global Market Perspective
10. Reportlinker Adds Radiopharmaceuticals - A US and European Market Analysis
11. Reportlinker Adds Ambulatory and Bathroom Aids - A Worldwide Market Review
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/17/2017)... , Feb. 17, 2017   Risperdal lawsuits involving ... allegedly associated with use of the atypical antipsychotic medication ... Court of Common Pleas, where the state,s ... program. According to a notice posted on the ... a meeting on March 9, 2017 at 11:00 a.m. ...
(Date:2/17/2017)...   FormFast , the leader in electronic forms ... Engage , one of the largest MEDITECH partners ... will serve as the forms automation and electronic signature ... .  FormFast is a MEDITECH collaborative ... enhance the electronic health record. FormFast,s technology bridges clinical ...
(Date:2/17/2017)... Feb. 17, 2017  BioDigital, Inc., creators of ... of their 3D body mapping technology with eClinicalWorks, ... new integration will be used to capture and ... of the human body. BioDigital pilots show using ... while also increasing the precision of clinical annotations ...
Breaking Medicine Technology:
(Date:2/18/2017)... Waltham, Massachusetts (PRWEB) , ... February 17, 2017 ... ... be the leading source of disruptive innovation in the industry, according to the ... Insights Reports are based on surveys of the NEJM Catalyst Insights Council, a ...
(Date:2/18/2017)... MANDEVILLE, La. (PRWEB) , ... February 18, 2017 ... ... Network released today provides the latest information and contact points to easily connect ... including home care, assisted living, and elder-care funding. It also conveys material on ...
(Date:2/17/2017)... ... 2017 , ... For the first time, International Scholarship and ... floor for the 2017 HIMSS Conference & Exhibition at the Orange ... than 40,000 healthcare industry professionals are expected at the conference, where they will ...
(Date:2/17/2017)... Texas (PRWEB) , ... February 17, 2017 , ... ... 8.0 at the HIMSS17 Conference & Exhibition in Orlando, Fla., February 19-23. Visitors ... version of the most widely used electronic patient signatures solution in healthcare ...
(Date:2/17/2017)... ... February 17, 2017 , ... Cancer diagnostics workflow solution ... February 20 – 22 in San Francisco. As part of the Tri-Conference expo, ... pathology workflow solution, as well as its new precision medicine platform, “Crosswalk Insight: ...
Breaking Medicine News(10 mins):