Navigation Links
New Genes Found for Inflammatory Bowel Disease in Children
Date:8/31/2008

e easier to deliver as well as more customized to each patient."

The study team also found an association between ulcerative colitis and genes on the major histocompatiblity complex (MHC) on chromosome 6. The MHC is a large group of genes with important roles in the immune system, and this finding may help refine diagnostic techniques that would allow physicians to administer more specific therapies to their patients.

The Center for Pediatric Inflammatory Bowel Disease at Children's Hospital currently treats 1,400 children annually for IBD, and has one of the world's largest clinical research programs for IBD. The Center for Applied Genomics, directed by Hakonarson, is currently the largest pediatric genotyping program in the world. The Center's highly automated analytic equipment scans each DNA sample for over half a million genetic markers.

Financial support for the study came from the National Institutes of Health, the IBD Family Research Council, the Crohn's and Colitis Foundation of America, the Koss Foundation, the NIH General Clinical Research Center of the Medical College of Wisconsin, the Primary Children's Medical Center Foundation, the Edmunds Fund, the Heineman Foundation, the Cotswold Foundation, and The Children's Hospital of Philadelphia, which funded all genotyping performed in the study.

Baldassano's and Hakonarson's co-authors included Struan Grant, Ph.D., Jonathan Bradfield, Ph.D., David A. Piccoli, M.D., Petar Mamula, M.D., Robert Grundmeier, M.D., and Dimitri Monos, Ph.D., all of Children's Hospital. Other co-authors were Subra Kugathasan, M.D. (formerly of the Medical College of Wisconsin and currently at Emory University), who is co-first author with Baldassano; Stephen Guthery, M.D., of the University of Utah; Gitit Tomer, M.D., and Lee Denson, M.D., of Cincinnati Children's Hospital Medical Center; Salvatore Cucchiara, M.D., Ph.D., of Sapienza University, Rome, Italy; and Vito Annese, M.D., of "Casa Sollievo della
'/>"/>

SOURCE Children's Hospital of Philadelphia
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. National Jewish, Brigham and Womens Awarded $37 Million to Identify Genes and Other Risk Factors that Influence the Development of COPD
2. KineMed Presents Preclinical Data for Investigational Agent Demonstrating Neurogenesis and Confirming Improvements in Behavioral Model
3. Intradigm Study Shows Ability of siRNAs Systemically Delivered With TargeTran(TM) System to Suppress Tumor-Induced Angiogenesis in Mice
4. Interim Analysis Supports Continuation of Cell Genesys VITAL-1 Phase 3 Clinical Trial of GVAX Immunotherapy for Prostate Cancer
5. Steps Toward Stopping Autoimmune Disease: International Consortium Identifies Genes Linked to Lupus
6. Genomic Health Announces Identification of Genes Associated With Colon Cancer Recurrence Across Multiple Studies
7. ADVENTRX to Present ANX-201 Preclinical Data at Keystone Symposia HIV Pathogenesis Conference
8. deCODE Launches a DNA-Based Test for Assessing Risk of Prostate Cancer on the Back of the Discovery of New Prostate Cancer Genes
9. Cell Genesys Reports Association Between Immune Response and Patient Survival in Phase 2 Trial of GVAX Immunotherapy for Prostate Cancer
10. CorMatrix(R) Announces Intramyocardial Injection of Emulsified ECM Technology(TM) Demonstrates Enhanced Angiogenesis and Improved Cardiac Function in a Preclinical Model
11. Transgenomic Establishes Collaboration With the National Cancer Institute to Investigate Mitochondrial Genome and Associated Nuclear Genes in Cancer Cell Lines
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/31/2015)... 2015  In today,s ever-changing marketplace, call centers must ... increasingly connected, and increasingly impatient with slow service. The ... channels and tools is driving call centers to explore ... According to research by benchmarking firm, Best Practices, ... in a call center study realize the impact of ...
(Date:7/31/2015)... The Physician-Patient Alliance for Health & ... 2015, "Surviving Your Hospital Stay: Physician-Patient Alliance for ... A sentence was omitted from the ... "PPAHS is a member of the National Coalition to ... on the National Coalition to Promote Continuous Monitoring of ...
(Date:7/31/2015)... 2015 Egalet Corporation (Nasdaq: EGLT ... focused on developing, manufacturing and marketing innovative pain ... announced underwritten public offering of 7,666,667 shares of ... of $11.25 per share. The shares of common ... upon the exercise in full by the underwriters ...
Breaking Medicine Technology:Best Practices in Building World-Class Consumer & Over-the-Counter Call Centers 2Egalet Announces Closing of Public Offering of Common Stock and Exercise in Full of Underwriters' Option to Purchase Additional Shares 2Egalet Announces Closing of Public Offering of Common Stock and Exercise in Full of Underwriters' Option to Purchase Additional Shares 3Egalet Announces Closing of Public Offering of Common Stock and Exercise in Full of Underwriters' Option to Purchase Additional Shares 4
... to be held on Wednesday, August 6, 2008 at 8:00 ... ... 5 Isolagen(TM), Inc. (Amex:,ILE) announced today positive top-line efficacy and safety ... the,Isolagen Therapy(TM) for the treatment of nasolabial folds, or wrinkles.,Each study, conducted ...
... WHIPPANY, N.J., Aug. 5 Nexgen Spine, a ... treatment of,degenerative disc disease, announced today that it ... Lumbar Artificial Disc in the European,Union., "We ... has,received CE mark approval," said Alastair Clemow, Ph.D., ...
Cached Medicine Technology:Isolagen, Inc. Reports Positive Top-line Results from Pivotal Phase III Studies of Isolagen Therapy(TM) in Wrinkles: Studies Meet All Primary Efficacy Endpoints and are Statistically Significant 2Isolagen, Inc. Reports Positive Top-line Results from Pivotal Phase III Studies of Isolagen Therapy(TM) in Wrinkles: Studies Meet All Primary Efficacy Endpoints and are Statistically Significant 3Isolagen, Inc. Reports Positive Top-line Results from Pivotal Phase III Studies of Isolagen Therapy(TM) in Wrinkles: Studies Meet All Primary Efficacy Endpoints and are Statistically Significant 4Isolagen, Inc. Reports Positive Top-line Results from Pivotal Phase III Studies of Isolagen Therapy(TM) in Wrinkles: Studies Meet All Primary Efficacy Endpoints and are Statistically Significant 5Nexgen Spine Receives CE Mark Approval for the Physio-L(R) Artificial Disc 2
(Date:7/31/2015)... Chicago, IL (PRWEB) , ... July 31, 2015 , ... ... which is currently going on in Chicago at Grant Park. The festival ... every corner of North America to Chicago for the annual Lollapalooza. This unique ...
(Date:7/31/2015)... ... July 31, 2015 , ... Last week, the ... The store can be accessed by visiting http://www.curemeso.org/store . , “Our new ... The best part: whenever a product is purchased, the Meso Foundation receives a ...
(Date:7/31/2015)... (PRWEB) , ... July 31, 2015 , ... There’s no ... possible, even when it comes time to cook the next meal, making July the ... July by practicing best grilling tips and recipes. , Make the next cookout different ...
(Date:7/31/2015)... ... July 31, 2015 , ... Coco Libre announced today that ... and VIPs at the 2015 Vans US Open of Surfing, July 25 through August ... claim “no added sugar” on the market, is a natural choice given the Open’s ...
(Date:7/31/2015)... CA (PRWEB) , ... July 31, 2015 , ... According to the article ... floor of the Pasadena courthouse was contained and extinguished by the city’s fire department before ... in the building at the time of the fire, and it was a fire alarm ...
Breaking Medicine News(10 mins):Health News:Cheap 2015 Lollapalooza Tickets: Ticket Down Slashes Ticket Prices on Lollapalooza Tickets at Grant Park in Chicago for Saturday, August 1st and Sunday, August 2nd 2Health News:Mesothelioma Organization Launches New Store 2Health News:Mesothelioma Organization Launches New Store 3Health News:King Kullen Honors National Hot Dog and Blueberry Month 2Health News:King Kullen Honors National Hot Dog and Blueberry Month 3Health News:Coco Libre Brings Eco-conscious Hydration to Vans US Open of Surfing 2Health News:Article on Recent Pasadena Courtroom Fire Highlights the Effectiveness of Fire Alarm Systems, Says Fire Protection Group Inc 2Health News:Article on Recent Pasadena Courtroom Fire Highlights the Effectiveness of Fire Alarm Systems, Says Fire Protection Group Inc 3
... Weight-Loss Plan Adapts to Dieter,s LifestyleOWINGS MILLS, Md., March ... today announced the Grand Opening of a new Pikesville, ... Weight Control Center is located at Festival at Woodholme, ... to help clients lose weight fast and then maintain ...
... who have high blood pressure or heart disease should avoid ... to be published online Wednesday in the Annals of ... drank two cans a day of a popular energy drink ... No significant changes in EKG measurements were reported. , The ...
... March 25 /PRNewswire/ - Medical device company, Intelligent ... agreement with the Arabian Medical Marketing Co. Ltd. ... Under the terms of the agreement, AMCO will ... Systems, RIVA System (Robotic IV Automation) across the ...
... Speedy Whittier one of the nation,s premier ... Inc. a leader in corporate Unified Communications ... that removes business obstacles, increases responsiveness to internal ... Speedy Whittier. The Zultys all-in-one solution provided ...
... tiny chirping frog and an elegant striped gecko are ... a Conservation International (CI) Rapid Assessment Program (RAP) expedition ... were announced today following analysis of the species that ... a month-long exploration of Papua New Guinea,s central mountains. ...
... MINNEAPOLIS, March 25 Minneapolis-based Eniva Nutraceutics(TM) announces ... its group of highly accomplished network marketing professionals. ... complement to Eniva,s already expansive community of worldwide, ... Harstads (harstads.biz) were top company performers throughout an ...
Cached Medicine News:Health News:Revolutionary Weight-Loss Center Opens in Pikesville 2Health News:Energy drinks may be harmful to people with hypertension, heart disease 2Health News:IH Systems Enters the Middle Eastern Medical Device Market 2Health News:Sir Speedy Whittier and Zultys Announce Advanced Unified Communications Deployment -- Zultys Solution Boosts Responsiveness, Cuts Costs 2Health News:Sir Speedy Whittier and Zultys Announce Advanced Unified Communications Deployment -- Zultys Solution Boosts Responsiveness, Cuts Costs 3Health News:Sir Speedy Whittier and Zultys Announce Advanced Unified Communications Deployment -- Zultys Solution Boosts Responsiveness, Cuts Costs 4Health News:Spiders, frogs and gecko among exciting discoveries found in Papua New Guinea 2Health News:Spiders, frogs and gecko among exciting discoveries found in Papua New Guinea 3Health News:Former Amway/Quixtar Diamond Leaders Find New Home at Eniva Nutraceutics 2
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: