Navigation Links
New England Journal of Medicine Publishes Results From a RELISTOR Phase 3 Clinical Study
Date:5/28/2008

Study Demonstrated Efficacy of RELISTOR for Use in Advanced-Illness

Patients with Opioid-Induced Constipation

COLLEGEVILLE, Pa. and TARRYTOWN, N.Y., May 28 /PRNewswire-FirstCall/ -- Wyeth Pharmaceuticals, a division of Wyeth (NYSE: WYE), and Progenics Pharmaceuticals, Inc. (Nasdaq: PGNX) today announced the publication of results from a pivotal phase 3 trial of RELISTOR(TM) (methylnaltrexone bromide) subcutaneous injection in the May 29, 2008 issue of the New England Journal of Medicine. RELISTOR is a newly approved therapy for the treatment of opioid-induced constipation (OIC) in patients with advanced illness who are receiving palliative care, when response to laxative therapy has not been sufficient.

The clinical study showed that significantly more OIC patients with advanced illness experienced bowel movements (laxation) within four hours of receiving their first dose of subcutaneous RELISTOR than patients receiving placebo, without the use of a rescue laxative (48 percent vs. 15 percent; P<0.001). The study also demonstrated that RELISTOR did not impair the ability of opioids to provide pain relief, and the drug was generally well tolerated.

"Effectively managing pain is critical for patients with advanced illness," says Jay Thomas, M.D., Ph.D., a lead author of the study and Clinical Medical Director of The San Diego Hospice and the Institute for Palliative Medicine. "However, the side effects associated with many pain medications can represent a significant barrier to prov
'/>"/>

SOURCE Wyeth Pharmaceuticals
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7

Related medicine technology :

1. Berkery Noyes Represented The Thomson Corporation in the Sale of CenterWatch and New England Institutional Review Board to Jobson Medical Information
2. New England Journal of Medicine Study Shows ERBITUX(R) Improves Survival in Advanced Colorectal Cancer
3. The New England Journal of Medicine Publishes First Clinical Results for MedImmunes Chitinase-like Protein YKL-40 in Patients With Asthma
4. Studies Showing Significant Survival Improvement with Taxotere(R)-based Regimens in the Induction Treatment of Patients with Locally Advanced Head and Neck Cancer are Published in the Same Issue of the New England Journal of Medicine
5. Vaccine Study in New England Journal of Medicine Wrong in Concluding Mercury Exposures are Harmless, States SafeMinds
6. Results from Study Evaluating PROCRIT(R) in Intensive Care Unit Patients Published in New England Journal of Medicine
7. Blood Spot Technology at ZRT Highlighted in March Issue of Journal of Diabetes Science & Technology - A Convenient Alternative to Serum Testing for Health Screening
8. Anesiva Announces Publication of Phase 3 Zingo(TM) Data in the Journal Pediatrics
9. Video: The Journal, Human Genetics, Publishes Results Supporting Interleukin Genetics Heart Health Test
10. Genetic Immunity Announces Data Related to the DermaVir Nanomedicine Patch in the Journal of Immunology
11. Three Dimensional Visualization of Right Ventricle Provides Important Information for Treatment of Patients with Tetralogy of Fallot, According to a Study in The American Journal of Cardiology
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/1/2014)... DIEGO , Oct. 1, 2014 ... molecular diagnostics, announced today that Eli Diamond ... Kettering Cancer Center (MSK), presented clinical data from ... precision cancer monitoring platform for the determination of ... a liquid biopsy.  The results were presented to ...
(Date:10/1/2014)... Oct. 1, 2014   Royal Philips ... announced its eCareCoordinator and eCareCompanion telehealth applications have ... Drug Administration (FDA). A part of Philips Hospital ... eCareCoordinator and eCareCompanion are focused on patient care ... applications to be available through the cloud-based digital ...
(Date:10/1/2014)... Switzerland , October 1, 2014 ... Genomics and Next Generation Sequencing (NGS) data analysis, today ... run full cystic fibrosis analysis in a single NGS ... characterisation of all types of variants in a single ... Until now, it has not been possible to simultaneously ...
Breaking Medicine Technology:Clinical Performance of Trovagene's Precision Cancer Monitoring Platform Presented at Second Annual International ECD Medical Symposium 2Clinical Performance of Trovagene's Precision Cancer Monitoring Platform Presented at Second Annual International ECD Medical Symposium 3Clinical Performance of Trovagene's Precision Cancer Monitoring Platform Presented at Second Annual International ECD Medical Symposium 4Philips Secures 510(k) Clearance to Market the First Clinical Applications for its new Digital Health Platform 2Philips Secures 510(k) Clearance to Market the First Clinical Applications for its new Digital Health Platform 3Philips Secures 510(k) Clearance to Market the First Clinical Applications for its new Digital Health Platform 4Sophia Genetics Launches Full CFTR Analysis in Single Clinical Grade NGS Experiment 2
... heart organizations representing cardiologists and cardiothoracic surgeons released ... aortic valve replacement (TAVR) programs. The recommendations are ... aortic stenosis, a form of valvular heart disease, ... Since the Food and Drug ...
... Calif., March 1, 2012  Heritage Provider Network presented checks ... Heritage Health Prize competition at the Strata Conference in ... the 12 month mark. Once again, ... competition, winning the top spot.  Players include David Vogel, ...
Cached Medicine Technology:Leading Cardiovascular Organizations Release Credentialing Recommendations for Heart Valve Replacement Procedure 2Leading Cardiovascular Organizations Release Credentialing Recommendations for Heart Valve Replacement Procedure 3Leading Cardiovascular Organizations Release Credentialing Recommendations for Heart Valve Replacement Procedure 4Leading Cardiovascular Organizations Release Credentialing Recommendations for Heart Valve Replacement Procedure 5Heritage Provider Network Awards $80,000 to the Progress Prize Winners in the $3Million Heritage Health Prize Contest at the Strata Conference in Santa Clara, California 2Heritage Provider Network Awards $80,000 to the Progress Prize Winners in the $3Million Heritage Health Prize Contest at the Strata Conference in Santa Clara, California 3
(Date:10/1/2014)... of scientists has shown that more than 80 per ... drugs. , The study found that medicines called ,JAK ... genetic mutation that is present in more than 80 ... currently used, or are in clinical trials, for diseases ... , Bowel cancer is the second-most common cancer in ...
(Date:10/1/2014)... a policy focus on expanding access to care ... continues to have significant dental disease. In this ... American Dental Association , researchers from Tufts University ... Dental Medicine report on the first large-scale survey ... by caregivers to adults with developmental disabilities. The ...
(Date:10/1/2014)... Hills, CA (PRWEB) October 01, 2014 ... internationally-franchised Fit Body Boot Camp fitness boot camps, he’s ... selling personal training , with sold out business summits, ... stint as marketing consultant to a recent Spike TV ... Keuilian says that now is the time for personal ...
(Date:10/1/2014)... October 01, 2014 Farmington Company ... a redefined mission and visual identity helping brokers, ... partnering with them to create greater benefit communication ... that focuses on empowering customers to better leverage ... The crown jewel of the rebrand is the ...
(Date:10/1/2014)... Jupiter, FL (PRWEB) October 01, 2014 ... Begley, Jr., scheduled to broadcast on Monday, October 20, ... In this episode, Innovations will go behind the scenes ... prevention programs. This segment will explore the practical help ... young adults, which teaches the warning signs of abuse, ...
Breaking Medicine News(10 mins):Health News:Eighty percent of bowel cancers halted with existing medicines 2Health News:To improve oral health of adults with developmental disabilities, support caregivers 2Health News:To improve oral health of adults with developmental disabilities, support caregivers 3Health News:Bedros Keuilian Shares Tips on Selling Personal Training for the Holidays 2Health News:Bedros Keuilian Shares Tips on Selling Personal Training for the Holidays 3Health News:Farmington Company Launches Rebrand and New Positioning 2Health News:Innovations to Explore Breakthroughs in Health and Wellness in Upcoming Episode Airing Monday, October 20, 2014 via Discovery Channel 2
... offering Indian companies the opportunity to attend New Frontiers 2007, ... seeks to help international companies that are keen to expand ... business and understanding of the market. ... 7th of March 2007, will be the largest gathering of ...
... severe nerve pain – by aiming drugs at a previously ... Utah scientists who study the venoms of deadly, sea-dwelling cone ... a chronic and debilitating form of pain suffered by hundreds ... a University of Utah research professor of biology, and research ...
... narrowing of the arteries, due to deposition of substances ... time, the plaque build–up may block the blood flowing ... ,But, Canadian researcher Dr. Sanaz Piran and ... presented a report on the early onset of atherosclerosis ...
... cancer prevention has advanced to the point where researchers are ... and treat cancer. The// Researchers now say they can detect ... the presence of two proteins in men they say will ... ,All of these novel findings need much more ...
... to evaluate the support available to the estimated 200 ... disease. Taking// cognizance of the burgeoning malady, the theme ... disadvantaged and the vulnerable’ amply reflects the cardinal purpose ... in diabetes management seeks to draw attention towards the ...
... anti-TNF therapy that has FDA approval for treating ... children with juvenile rheumatoid// arthritis, according to research ... Rheumatology Annual Scientific Meeting in Washington, DC. ... adults with moderate to severe rheumatoid arthritis, targets ...
Cached Medicine News:Health News:A Hot Date with the Lucrative UK Pharma Market 2Health News:A Novel Technique That Detects "Cancer Genes" From The Breath Of Smokers 2Health News:A Novel Technique That Detects "Cancer Genes" From The Breath Of Smokers 3Health News:A Novel Technique That Detects "Cancer Genes" From The Breath Of Smokers 4Health News:A Novel Technique That Detects "Cancer Genes" From The Breath Of Smokers 5Health News:A Novel Technique That Detects "Cancer Genes" From The Breath Of Smokers 6Health News:A Novel Technique That Detects "Cancer Genes" From The Breath Of Smokers 7Health News:A Novel Technique That Detects "Cancer Genes" From The Breath Of Smokers 8Health News:A Novel Technique That Detects "Cancer Genes" From The Breath Of Smokers 9Health News:A Novel Technique That Detects "Cancer Genes" From The Breath Of Smokers 10Health News:The Holy Grail of Diabetes Management 2Health News:The Holy Grail of Diabetes Management 3Health News:Adalimumab Proves Effective for Children with Juvenile Rheumatoid Arthritis 2
Inquire...
Inquire...
Inquire...
Inquire...
Medicine Products: