Navigation Links
New England Biolabs Receives Award to Develop Novel Enzymatic Reagents for Epigenetic Studies
Date:9/15/2010

IPSWICH, Mass., Sept. 15 /PRNewswire/ -- New England Biolabs (NEB) has announced that it has received fast track SBIR funding of $1.22 million to fund the research and development of novel enzymatic reagents for epigenetic studies.

(Logo: http://photos.prnewswire.com/prnh/20090921/NE79207LOGO-b)

(Logo: http://www.newscom.com/cgi-bin/prnh/20090921/NE79207LOGO-b)

New England Biolabs is committed to developing tools that advance epigenetics research and discovery, and offers a growing range of products for use in this area. Scientists at NEB recently identified the MspJI family of restriction enzymes and demonstrated their utility in mapping epigenetic modifications. This family of enzymes has the ability to cleave out small fragments of DNA for use in applications such as next generation sequencing, as well as to identify 5-hydroxymethylcytosine* modifications, when used in conjunction with T4 B-glucosyltransferase. Funding will go towards continuing this work, simplifying the study of epigenetic DNA modifications and expanding their potential as biomarkers.

"The discovery of MspJI and its homologs offers a significant opportunity for greatly expanding the role of restriction enzymes in epigenetics research," states Dr. Richard Roberts, Chief Scientific Officer at New England Biolabs. "The use of MspJI and other restriction enzymes in this family will simplify the study of DNA methylation and will accelerate our understanding of the role of 5-hydroxymethylcytosine in the epigenome."

About NEB

Established in the mid 1970's, New England Biolabs, Inc. is the industry leader in the discovery and production of enzymes for molecular biology applications and now offers the largest selection of recombinant and native enzymes for genomic research. NEB continues to expand its product offerings into areas related to PCR, gene expression, cellular analysis, epigenetics and RNA analysis. Additionally, NEB is focused on strengthening alliances that enable new technologies to reach key market sectors. New England Biolabs is a privately held company, headquartered in Ipswich, MA and has extensive worldwide distribution through a network of exclusive distributors, agents and five subsidiaries located in Canada, China, Germany, Japan and the UK. For more information about New England Biolabs visit www.neb.com.

* In addition to 5-methylcytosine (5-mC), 5-hydroxymethylcytosine (5-hmC) modifications have been identified in genomic DNAs. The biological role of 5-hmC with respect to epigenetic changes is not currently understood.


'/>"/>
SOURCE New England Biolabs
Copyright©2010 PR Newswire.
All rights reserved

Related medicine technology :

1. Results from Study Evaluating PROCRIT(R) in Intensive Care Unit Patients Published in New England Journal of Medicine
2. Vaccine Study in New England Journal of Medicine Wrong in Concluding Mercury Exposures are Harmless, States SafeMinds
3. Studies Showing Significant Survival Improvement with Taxotere(R)-based Regimens in the Induction Treatment of Patients with Locally Advanced Head and Neck Cancer are Published in the Same Issue of the New England Journal of Medicine
4. The New England Journal of Medicine Publishes First Clinical Results for MedImmunes Chitinase-like Protein YKL-40 in Patients With Asthma
5. New England Journal of Medicine Study Shows ERBITUX(R) Improves Survival in Advanced Colorectal Cancer
6. Berkery Noyes Represented The Thomson Corporation in the Sale of CenterWatch and New England Institutional Review Board to Jobson Medical Information
7. New England Journal of Medicine Publishes Results From a RELISTOR Phase 3 Clinical Study
8. The New England Journal of Medicine Publishes Study Investigating the Safety and Efficacy of Baxters Cell-Based Pandemic, Avian Flu Vaccine
9. The New England Journal of Medicine Publishes Nexavar(R) Study Demonstrating Significant Improvement in Overall Survival in Patients With Liver Cancer
10. New England Journal of Medicine Publishes Phase III Results of VELCADE(R) (Bortezomib) for Injection in Previously Untreated Multiple Myeloma Patients
11. Diamyd(R) Study Published in Prestigious New England Journal of Medicine
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/4/2017)... May 4, 2017  A new tight-tolerance microextrusion ... other highly-engineered materials, is being launched by Natvar, ... been developed in recent years to service a ... surgical applications. More expensive materials such as glass ... tubing due to their ability to consistently hold ...
(Date:5/3/2017)... , May 3, 2017  Kalorama Information notes ... nine percent next year and this is projected ... hematopoietic stem cell (HSCT) or bone marrow transplants ... technologies are well-suited for this task. This according ... publisher Kalorama Information. The various PCR-based methodologies, Sanger ...
(Date:5/2/2017)... and LONDON , May ... market intelligence, MarketResearch.com is pleased to announce a business ... that allows for the marketing and distribution of ... through the MarketResearch.com website. The new relationship ... complete product descriptions and tables of contents from research ...
Breaking Medicine Technology:
(Date:5/22/2017)... San Antonio, TX (PRWEB) , ... May 22, 2017 , ... ... It starts with a body squatted, stretched, jumped, toned and shaped through fitness programs. ... And it is, of course, finished off with an irresistible, radiant smile. CDA ...
(Date:5/21/2017)... ID (PRWEB) , ... May 20, 2017 , ... ... financial integration systems between ABC Financial Services and financial systems. , ... link or exported files that are electronically processed through GetLinked into their club’s ...
(Date:5/21/2017)... ... ... For more than 20 years United Cutlery has been distinguished by unique and ... to fantasy. United Cutlery has always been “Stronger. Sharper” than the competition and it ... a range of weapons and tools built for battle, the M48 line by United ...
(Date:5/19/2017)... ... May 19, 2017 , ... ... an upcoming episode of Innovations with Ed Begley, Jr., airing fourth quarter 2017 ... distributor of a clean, organic dietary supplement made from naturally occurring ingredients. Innovations ...
(Date:5/19/2017)... , ... May 19, 2017 , ... ... 2017 class of Beckman Young Investigators: , Victor Acosta, Ph.D. - University of ... University, Dan Fu, Ph.D. - University of Washington, Erik Grumstrup, Ph.D. - Montana ...
Breaking Medicine News(10 mins):