Navigation Links
New Discovery of Key Difference in Bile Acid Metabolism in Patients with Type 2 Diabetes May Suggest Underlying Disorder
Date:6/9/2008

First Extensive Report of Bile Acid Aberration in Type 2 Diabetes Patients

Warrants Further Study

EMERYVILLE, Calif. and PARSIPPANY, N.J., June 9 /PRNewswire-FirstCall/ -- KineMed, Inc., and Daiichi Sankyo, Inc., announced that researchers have discovered a key difference in bile acid metabolism in people with type 2 diabetes which may suggest a newly identified underlying disorder.

It has long been known that bile acids help the body absorb fat and cholesterol. In the last decade, we learned that bile acids are important signaling molecules that regulate the metabolism of glucose, fat, and energy. And until now, there has been only preliminary data suggesting alterations in bile acid metabolism in people with type 2 diabetes. Now new data highlight crucial alterations in bile acid metabolism in this population. Researchers reported results from the first controlled study addressing this issue, which they hope will lead to a better understanding of how bile acid metabolism is impacted in people with type 2 diabetes.

The study found that the most important bile acid, cholic acid (CA), had a significantly higher synthesis rate in people with type 2 diabetes than in patients with normal glucose levels. Researchers also learned that the rate at which deoxycholic acid (DCA) was recycled back into the liver (i.e. DCA input rate) was almost twice as great in those with type 2 diabetes as in the healthy subjects. In addition, the total amount of bile acid synthesized by the liver was elevated, although not statistically significantly, in people who have type 2 diabetes as compared to the healthy control group.

KineMed, Inc., a pathway-based drug discovery and development company, initiated the research which used their proprietary translational medicine technology, KineMarker(TM). The results from the study were presented at the American Diabetes Association's 68th Scientific Sessions. The research was funded with
'/>"/>

SOURCE KineMed, Inc.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7

Related medicine technology :

1. Discovery Leads to Earlier Diagnosis of Type 1 Diabetes
2. New Gene Discovery Suggests Which Patients CTIs Brostallicin May Benefit
3. Intra-Cellular Therapies Announces the Discovery of Potent Antidepressant Activity in ITI-007
4. Intra-Cellular Therapies Announces the Discovery of Potent Antidepressant Activity in ITI-007/ITI-722
5. Ono Enters into a New Fragment-Based Drug Discovery Agreement with Evotec
6. deCODE Launches a DNA-Based Test for Assessing Risk of Prostate Cancer on the Back of the Discovery of New Prostate Cancer Genes
7. FASgen Announces a New Discovery in Obesity Research
8. Orion Genomics Announces the Discovery of Novel Breast Cancer Biomarkers
9. Nobel Prize-Winning Discovery
10. FASgen Announces New Discovery for Treatment of Stroke
11. Ambrx Enters FGF-21 Type 2 Diabetes Drug Discovery Collaboration with Merck and Co. Inc.
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/1/2015)... LOUIS , July 1, 2015 New ... first quarter of 2015 compared to the same time ... the Express Scripts (NASDAQ: ESRX ) Exchange Pulse™ ... first quarter of 2014, the number of new exchange ... declined 18 percent in the first quarter of 2015. ...
(Date:6/30/2015)... EDINBURGH, Scotland , July 1, 2015 ... joins Nu C ana team   ... proprietary ProTide technology to develop and commercialise a portfolio ... Professor Chris McGuigan as Chief Scientific Officer. ... the ProTide technology. He is currently Professor of Medicinal ...
(Date:6/30/2015)... , June 30, 2015 Nortek Security ... NTK ) and a leader in the ... today announced it acquired mobile personal emergency response ... held Numera, Inc. Headquartered in ... easily implemented, mobile PERS products and cloud-based software ...
Breaking Medicine Technology:Express Scripts Provides First Look at 2015 Public Exchange Pharmacy Trends 2Express Scripts Provides First Look at 2015 Public Exchange Pharmacy Trends 3Express Scripts Provides First Look at 2015 Public Exchange Pharmacy Trends 4Express Scripts Provides First Look at 2015 Public Exchange Pharmacy Trends 5Internationally Renowned Medicinal Chemist Professor Chris McGuigan Appointed as NuCana's Chief Scientific Officer 2Internationally Renowned Medicinal Chemist Professor Chris McGuigan Appointed as NuCana's Chief Scientific Officer 3Nortek Security & Control Acquires Health and Wellness Technology Business from Numera 2Nortek Security & Control Acquires Health and Wellness Technology Business from Numera 3Nortek Security & Control Acquires Health and Wellness Technology Business from Numera 4
... 2, 2010 Fiscal first quarter revenue from ... $641 million Fiscal first quarter adjusted income from ... $0.87 per share Fiscal first quarter GAAP income ... per share Rx segment revenue grew 47 percent ...
... IRVINE, Calif., Nov. 2, 2010 Endologix, Inc. (Nasdaq: ... for aortic disorders, announced today the first clinical implant ... City Hospital in Auckland, New Zealand.  The procedure was ... of Interventional Radiology) and Andrew, Hill, MD (Associate Professor ...
Cached Medicine Technology:Perrigo Reports Record Earnings and Raises Full Year Adjusted EPS Guidance 2Perrigo Reports Record Earnings and Raises Full Year Adjusted EPS Guidance 3Perrigo Reports Record Earnings and Raises Full Year Adjusted EPS Guidance 4Perrigo Reports Record Earnings and Raises Full Year Adjusted EPS Guidance 5Perrigo Reports Record Earnings and Raises Full Year Adjusted EPS Guidance 6Perrigo Reports Record Earnings and Raises Full Year Adjusted EPS Guidance 7Perrigo Reports Record Earnings and Raises Full Year Adjusted EPS Guidance 8Perrigo Reports Record Earnings and Raises Full Year Adjusted EPS Guidance 9Perrigo Reports Record Earnings and Raises Full Year Adjusted EPS Guidance 10Perrigo Reports Record Earnings and Raises Full Year Adjusted EPS Guidance 11Perrigo Reports Record Earnings and Raises Full Year Adjusted EPS Guidance 12Perrigo Reports Record Earnings and Raises Full Year Adjusted EPS Guidance 13Perrigo Reports Record Earnings and Raises Full Year Adjusted EPS Guidance 14Perrigo Reports Record Earnings and Raises Full Year Adjusted EPS Guidance 15Perrigo Reports Record Earnings and Raises Full Year Adjusted EPS Guidance 16Perrigo Reports Record Earnings and Raises Full Year Adjusted EPS Guidance 17Perrigo Reports Record Earnings and Raises Full Year Adjusted EPS Guidance 18Perrigo Reports Record Earnings and Raises Full Year Adjusted EPS Guidance 19Endologix Announces First Clinical Implant of Ventana™ Stent Graft 2Endologix Announces First Clinical Implant of Ventana™ Stent Graft 3Endologix Announces First Clinical Implant of Ventana™ Stent Graft 4
(Date:7/1/2015)... ... ... Amada Senior Care, premier provider of non-medical in-home care and assisted living ... Mesa, Arizona location . Amada franchise partners Kris Patmos and Kimberly Perkins decided ... the area after years of experience in the sales and healthcare industries. Their grand ...
(Date:7/1/2015)... ... July 01, 2015 , ... After ... B. E. Smith, Tri-City Medical Center in Oceanside, Calif., has hired ... record of leading organization-wide compliance adaptation efforts and growing a focus on risk ...
(Date:7/1/2015)... ... July 01, 2015 , ... METTLER TOLEDO ... With larger-than-average weighing pans, ML-T balances give operators the room they need to ... extra real estate makes ML-T balances a perfect choice for day-to-day weighing in ...
(Date:7/1/2015)... ... July 01, 2015 , ... These listings will give ... placement, sober companionship and delivery to wilderness therapy or treatment facilities. Therapeutic ... clients with anxiety, ADHD, autism spectrum disorders, eating disorders, severe learning disabilities, addiction ...
(Date:7/1/2015)... ... , ... Nutritional Products International, a brand focused on the global marketing and ... ECRM Diet, Vitamin & Sports Nutrition conference in Tampa, Florida, where it made a ... show allows companies the chance to meet with a variety of the most influential ...
Breaking Medicine News(10 mins):Health News:Amada Senior Care Expands to Greater Phoenix Area 2Health News:Tri-City Medical Center Hires New Chief Compliance Officer 2Health News:Tri-City Medical Center Hires New Chief Compliance Officer 3Health News:METTLER TOLEDO Launches Compact ML-T Balances: Larger Pan Offers Greater Weighing Flexibility in Tight Spaces 2Health News:All Kinds of Therapy – Announces New Partnership Feature, Therapeutic Experts 2Health News:NPI Meets With Top Retail Figures at ECRM Conference 2
... levels may be to blame, , TUESDAY, Nov. 10 (HealthDay News) ... in your teens, a new study now suggests that extra weight ... , Reporting in the Nov. 10 issue of Neurology , ... doubles a woman,s risk of developing MS later in life compared ...
... ... planning and creative production, Upstate University Health Systems in Syracuse, New York, in partnership ... branding campaign for the Health System. , ... Mobile, AL (Vocus) November 10, 2009 -- After a year ...
... conducted by the Center for Autism and Related Disorders, Inc. ... form of hyperbaric oxygen therapy (HBOT) treatment for children with ... Therapy for Children with Autism" study reveals that HBOT, consisting ... not have a significant effect on symptoms of autism. This ...
... ... debate within health reform is to have policyholders select and pay extra for either a ... ... near-derailment of comprehensive health reform over abortion coverage and the possibility that the same thing ...
... ... , ... CA (PRWEB) November 10, 2009 -- The Medpedia Project today announced the addition of ... health community: Medpedia Answers for asking and answering medical and health questions; Medpedia Alerts ...
... ... finishing of cylindrical parts composed of hard materials such as ceramics, carbide and hardened ... from Brush Research Technology. , ... Los Angeles (PRWEB) November 10, 2009 -- Using exclusive, self-sharpening diamond crystals ...
Cached Medicine News:Health News:Teen Obesity Ups MS Risk in Women 2Health News:Teen Obesity Ups MS Risk in Women 3Health News:Upstate University Health System Launches Knowing Changes Everything Campaign in Partnership with Lewis Communications 2Health News:Upstate University Health System Launches Knowing Changes Everything Campaign in Partnership with Lewis Communications 3Health News:Center for Autism and Related Disorders Study Finds Hyperbaric Oxygen Therapy Ineffective Treatment for Children with Autism 2Health News:“Think Outside the Box” Blog Proposes Better Abortion Compromise for Health Reform 2Health News:Medpedia Project Expands Platform to Include Q&A, News & Analysis and Alerts 2Health News:Medpedia Project Expands Platform to Include Q&A, News & Analysis and Alerts 3Health News:Medpedia Project Expands Platform to Include Q&A, News & Analysis and Alerts 4Health News:Diamond Honing Tool Technology: The New Standard in Surface Finishing of Hard Materials 2
...
... QUANTA LiteTM ANA is an enzyme-linked ... of anti-nuclear antibodies (ANA) in human serum. ... in conjunction with clinical findings and other ... of rheumatic diseases such as systemic lupus ...
... Immuno Concepts manufactures slides that are ... technologist to decrease the number of pipetting ... patient sample dilutions on the slides. Ask ... procedure and these slides. These slide formats ...
... The ANA and ENA assays can ... negative for antinuclear antibodies, which are ... such as Systemic lupus erythematosus (Lupus), ... progressive systemic sclerosis, scleroderma, polymyositis, dermatomyositis, ...
Medicine Products: