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New Data Support High Complete Remission Rates With VELCADE(R) (Bortezomib) for Injection Based Therapies in Patients With Newly Diagnosed Multiple Myeloma

> 3:30 p.m. CT

-- Safety and Efficacy of Lenalidomide, VELCADE and dexamethasone in

Patients with Newly Diagnosed Multiple Myeloma: A Phase I/II Study

-- Lead investigator: Paul Richardson, M.D., Associate Professor of

Medicine, Harvard Medical School; Clinical Director, Jerome Lipper

Multiple Myeloma Center, Dana-Farber Cancer Institute, Boston

-- Abstract #8520: Oral presentation session: Saturday, 31 May,

4:15 p.m. CT

Relapsed/Refractory Multiple Myeloma

Data will be presented from several studies of VELCADE based therapies for the treatment of relapsed MM. These data are expected to support the value of adding VELCADE in combination with emerging and established agents, including patients with renal insufficiency.

Non-Hodgkin's Lymphoma (NHL)

Beyond multiple myeloma, the Company continues to pursue and support trials in NHL, which is expected to be the next potential growth opportunity for VELCADE. Currently, VELCADE is the only approved therapy for patients with previously treated mantle cell lymphoma (MCL), the most aggressive form of NHL. ASCO-related data will be featured for VELCADE in combination with established agents in patients with relapsed MCL, indolent NHL and Waldenstrom's Macroglobulinemia, including:

-- Primary therapy of Waldenstrom's Macroglobulinemia with bortezomib,

dexamethasone and rituximab: results of WMCTG clinical trial 05-180

-- Lead investigator: Steven Treon, M.D., Ph.D., Assistant Professor in

Medicine, Harvard Medical School

-- Abstract #8519: Oral presentation session: Saturday, 31 May,

3:45 p.m. CT

In addition to these highlighted trials, the Company is expected to fully accrue patients by the first half of this year for a large, registration-enabling Phase III trial in follicular lymphoma. The trial is designed under a special protocol assessment (SPA) with

SOURCE Millennium Pharmaceuticals, Inc.
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