New Data Shows Ongoing Benefits of Percutaneous MitraClip(R) Device for Patients With Mitral Reg... (ients who are interested in participatio...)

New Data Shows Ongoing Benefits of Percutaneous MitraClip(R) Device for Patients With Mitral Regurgitation

Date:10/24/2007

ients who are interested in participation in the study can call 1-877-MY-MR-FIX (1-877-696-7349).

About the MitraClip Device Procedure

Evalve's Percutaneous Mitral Repair (PMR) procedure is performed by interventional cardiologists in the catheterization laboratory. The heart beats normally during the procedure, and therefore does not require a hear-lung bypass machine. In addition to improving blood flow through the heart, the procedure may also relieve symptoms such as fatigue and shortness of breath that often affect patients with significant MR. After treatment, patients generally return to modified activity within two days to one week. The MitraClip device appears to improve quality of life and help MR patients avoid or delay surgery, preserving surgical options (valve repair or replacement) if it becomes necessary.

About Mitral Regurgitation

Mitral regurgitation (MR), the most common type of heart valve insufficiency occurs when the heart's mitral valve does not close properly. Both the American Heart Association and the American College of Cardiology recommend open-heart surgery to repair or replace the mitral valve for patients who suffer from moderate-to-severe (Grade 3+) and severe (Grade 4+) MR; open heart surgery is not recommended for patients with 1-2+ MR.

An estimated four million people in the United States have significant (>2+) MR, with an annual incidence of 250,000 newly diagnosed patients. However, only 20 percent of these patients, or approximately, 50,000, undergo surgery each year; the other 200,000 remain affected by MR.

For more information about mitral regurgitation or the EVEREST II study, please visit http://www.mitralregurgitation.org.

About Evalve, Inc.

Evalve, Inc. (Menlo Park, Calif.) was incorporated in 1999 to design, develop, manufacture, and market innovate devices to enable percutaneous repair of cardiac valves. The com
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