Navigation Links
New Data Shows Investigational Triple Antihypertensive Combination Therapy Significantly Lowers Blood Pressure in Hard-to-Treat Patients with Hypertension and Diabetes
Date:6/28/2010

diabetes cohort compared to the dual combination therapy groups (38.5/21.5 mm Hg versus 28.9 to 31.9/14.7 to 17.8 mm Hg, respectively, p<0.0001).(1) Mean baseline blood pressure for the non-diabetes cohort was 167.4/101.4 mm Hg in the triple combination therapy group compared to 167.3-168.6/101.2-101.6 mm Hg in the dual combination therapy groups.(1)

Publication-Only Abstract on Ethnicity and BMI Subgroup Analysis

Two additional pre-specified subgroup analyses of the TRINITY study by ethnicity (Hispanic/Latino or non-Hispanic/Non-Latino) and body mass index (BMI) category of <30 kg/m2 or greater than or equal to 30 kg/m2 found that the triple combination therapy was similarly more effective than dual regimens, regardless of the ethnicity and BMI of the patient.(4)

It is estimated that hypertension affects 21 percent of Hispanic adults (18 years or older) in the U.S.(5)  Additionally, the majority of patients with high blood pressure are overweight, with the condition being six times more frequent in obese people.(6)

Results for the ethnicity subgroup analysis [Hispanic or Latino (n=369, 14.8 percent) and non-Hispanic or non-Latino (n=2,122)] showed that the olmesartan medoxomil / amlodipine / hydrochlorothiazide (40/10/25 mg) triple combination therapy produced a significantly greater mean reduction in seated diastolic blood pressure (P less than or equal to 0.0236) and a greater reduction in seated systolic blood pressure from baseline to week 12 compared with each dual combination therapy regardless of ethnicity.(4)  Additionally, in both non-obese patients (n=937, BMI of <30 kg/m2) and obese patients (n=1,555, BMI of greater than or equal to 30 kg/m2), the triple combination therapy (40/10/25 mg) resulted in significantly greater LS mean reductions in seated diastolic blood pressure (P less than or equal
'/>"/>

SOURCE Daiichi Sankyo
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7

Related medicine technology :

1. Phase 2 Data for Ultra-Long-Acting Insulin Degludec Shows the Potential to Effectively Lower Blood Sugar, Including When Used Three Times a Week
2. Syndax Pharmaceuticals Entinostat Shows Clinical Promise in Patients with Advanced Hormone Refractory Breast Cancer
3. Highmark Study Shows Integrated Medical and Pharmacy Benefits Lower Costs, Promote Better Health
4. New Report Shows Record Number of Medicines Currently in Development to Treat Diabetes
5. Drug in New Class of Targeted Therapies Shows Early Promise Against Blood-Related Cancers
6. New Study Shows ENJUVIA® Significantly Reduced Sleep Time Awakenings Caused by Hot Flashes in Postmenopausal Women
7. Implanted Sleep Device Shows Promising Early Results
8. Data Shows Ambulance Fees Will Deter Emergency Calls for Help
9. New Study Shows 84 Percent Reduction in Post-Cesarean Section Infections Through Comprehensive Prevention Strategy
10. Novavaxs Seasonal Influenza VLP Vaccine Candidate Shows Positive Results in a Phase II Clinical Trial in Older Adults
11. Study Shows Superior Efficacy for TAXUS(R) Express(R) Stents at One Year Compared to Bare-Metal Stents in Diabetic Patients Experiencing Heart Attack
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/28/2015)... , FARUM, Denmark and ... On July 31, 2015 the US Food and Drug Administration ... of Major Depressive Disorder in adult patients who have failed ... current episode. TMS is a non-invasive technique for stimulating neural ... suffering from Major Depressive Disorder. The procedure has been proven ...
(Date:8/28/2015)... y LONDRES, 28 de agosto de ... PHIA) anunció hoy su participación en el  Congreso ... sus soluciones cardiológicas más recientes y novedosas, entre ... que conectan a las personas y la tecnología ... ayudar a diagnosticar, guiar los tratamientos y permitir ...
(Date:8/27/2015)... Aug. 27, 2015  A recent study by ... Journal, compared the Arthrosurface HemiCAP® Wave implant, which ... an "onlay" design implant for isolated patellofemoral disease. ... function and pain scores, none of the patients ... (OA). However, 53% of the patients in the ...
Breaking Medicine Technology:Therapy System for Treating Major Depressive Disorder Receives FDA Clearance 2Therapy System for Treating Major Depressive Disorder Receives FDA Clearance 3Philips presenta nuevas soluciones cardiológicas integradas para desarrollar procedimientos menos invasivos 2Philips presenta nuevas soluciones cardiológicas integradas para desarrollar procedimientos menos invasivos 3Philips presenta nuevas soluciones cardiológicas integradas para desarrollar procedimientos menos invasivos 4Philips presenta nuevas soluciones cardiológicas integradas para desarrollar procedimientos menos invasivos 5Study Demonstrates Dramatic Reduction in Progression of Osteoarthritis with the Arthrosurface "Inlay" Patellofemoral Implant Design Compared to Traditional "Onlay" Implant 2Study Demonstrates Dramatic Reduction in Progression of Osteoarthritis with the Arthrosurface "Inlay" Patellofemoral Implant Design Compared to Traditional "Onlay" Implant 3
(Date:8/28/2015)... Madre, CA (PRWEB) , ... August 28, 2015 ... ... solutions to wound center management, Decatur County Memorial Hospital recently transitioned management companies ... model of Wound Center Management for their outpatient wound center. , Transitioning ...
(Date:8/28/2015)... ... August 28, 2015 , ... Approximately ... the Zoo to celebrate children helping children, a thank you to the many ... Ohio have contributed to the United Methodist initiative to end malaria deaths. , ...
(Date:8/28/2015)... ... August 28, 2015 , ... An article published August 19th ... LaRocco has gone through to open a pizzeria in Westchester. Mr. LaRocco was aware ... take several months, but the current process, having already gone on for over a ...
(Date:8/28/2015)... ... August 28, 2015 , ... For Dallas, the time is nearing for ... subsidiary USPI Tenet Health. , The American Heart Association hosts their well-known Heart Walk ... believe that together, a difference can be made. Walkers can participate in the cause ...
(Date:8/28/2015)... ... 2015 , ... As reported by Medical Daily on August 22 , ... that last for two years, the longest of any cellulite reduction system currently on ... a long-lasting, effective solution for their cellulite, according to Dr. Robert Weiss, director of ...
Breaking Medicine News(10 mins):Health News:Decatur County Memorial Hospital Transitions Wound Center Management To Wound Care Advantage and the Luvo Operating System 2Health News:Decatur County Memorial Hospital Transitions Wound Center Management To Wound Care Advantage and the Luvo Operating System 3Health News:Decatur County Memorial Hospital Transitions Wound Center Management To Wound Care Advantage and the Luvo Operating System 4Health News:Saturday’s United Methodist Event at Columbus Zoo Celebrates Imagine No Malaria 2Health News:Saturday’s United Methodist Event at Columbus Zoo Celebrates Imagine No Malaria 3Health News:Article on Building Approval Process for LA Business Highlights the Need for a Bridge Between Businesses and City Officials, says Fire Protection Group Inc. 2Health News:North Central Surgical Center’s Subsidiary Participates in Walk 2Health News:Maryland Dermatologists Discuss Non-Invasive Cellulite Reduction System Cellfina Receiving 2-Year FDA Clearance 2Health News:Maryland Dermatologists Discuss Non-Invasive Cellulite Reduction System Cellfina Receiving 2-Year FDA Clearance 3
... that the U.S. Department of Defense is funding to ... hospital patients from deadly infections, thanks to recent funding ... and Academic Research (NYSTAR). ,The funding comes as ... to treat, are on the rise. ,The ...
... UK recommendations for the availability of paracetamol, a common painkiller ... to limit the impact of excess doses of paracetamol, which ... drug is highly toxic to the liver in large amounts. ... to a maximum of 32 tablets of 500 mg each ...
... Volker Heussler of the Bernhard Nocht Institute for Tropical Medicine ... the immune system by killing the liver cell occupied by ... man, malarial parasites head to the liver and then to ... how the parasite avoids the immune system. Heussler's team used ...
... study on Rheumatic disease in women has shown that ... who have no genetic predisposition// to the disease. ... chronic inflammation of the joints. The cause of ... environmental factors is thought to trigger the immune system ...
... researchers found that altering the fatty acid ratio found in ... and decrease the amount of omega-6 fatty acids// may reduce ... in the Aug. 1 issue of the journal Clinical Cancer ... to show the impact of diet on lowering an inflammatory ...
... the brain of older patients with atrial fibrillation whether ... therapy// , according to a new study. ... from the University of California, San Francisco, Massachusetts General ... Boston University School of Medicine. ,Using a ...
Cached Medicine News:Health News:Device Can "Battle" Hospital Infections 2Health News:Device Can "Battle" Hospital Infections 3Health News:UK Recommendations On Painkillers Flaunted 2Health News:Altering Fatty Acid Levels in Diet May Reduce Prostate Cancer Growth Rate 2Health News:Risk of Brain Hemorrhage Rises with Old Age 2
Conventional Digitally-Controlled Water Baths...
... consists of two principal components. The AB5000 Console ... blood pumps and can be used either in ... hospitals. The AB5000 Ventricle is a disposable blood ... both ventricles of the heart and is designed ...
... The Dengue virus belongs to the Flavavirus ... commonly throughout the tropics.,Symptoms of Dengue fever ... pain in the back and limbs, lymphadenopathy,maculopapular ... for professional use as an aid in ...
... intracellular parasite Toxoplasma gondii and,may be contracted ... with cat,feces containing oocytes. If a pregnant ... the fetus through the placenta. This can ... of mortality and malformation.,This test is intended ...
Medicine Products: