Navigation Links
New Data Shows Investigational Triple Antihypertensive Combination Therapy Significantly Lowers Blood Pressure in Hard-to-Treat Patients with Hypertension and Diabetes
Date:6/28/2010

PARSIPPANY, N.J., June 28 /PRNewswire/ -- Preliminary results of a pre-specified subgroup study analysis of patients with diabetes and hypertension demonstrated that the investigational triple combination therapy of olmesartan medoxomil / amlodipine / hydrochlorothiazide (40/10/25 mg) resulted in a statistically significant greater Least Squares (LS) mean reduction in blood pressure from baseline at week 12 (37.9/22.0 mm Hg versus 26.4-28.0/14.7-17.6 mm Hg, P less than or equal to 0.0013) as compared to corresponding dual combination therapy [olmesartan medoxomil (40 mg) / amlodipine (10 mg); olmesartan medoxomil (40 mg) / hydrochlorothiazide (25 mg); or amlodipine (10 mg) and hydrochlorothiazide (25 mg)].(1) Blood pressure is more difficult to control among patients with hypertension and diabetes compared to patients with hypertension alone.(2) These findings were presented today during a poster presentation at the American Diabetes Association (ADA) 70th Annual Scientific Sessions in Orlando, FL.

This analysis of the TRINITY study (Triple Therapy with Olmesartan Medoxomil, Amlodipine, and Hydrochlorothiazide in Hypertensive Patients Study) also demonstrated that the investigational triple combination therapy (40/10/25 mg) enabled more patients with hypertension and diabetes to achieve blood pressure goal of <130/80 mm Hg at week 12 as compared to corresponding dual combination therapies (41.1 percent in the triple combination group versus 10.1 to 16.3 percent in the dual combination groups, P less than or equal to 0.0002).(1) Baseline blood pressures for those patients receiving the triple combination therapy and corresponding dual combination therapies were 170.7/98.3 mm Hg and 170.7-173.1/97.8-99.3 mm Hg, respectively.(1)


'/>"/>
SOURCE Daiichi Sankyo
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7

Related medicine technology :

1. Phase 2 Data for Ultra-Long-Acting Insulin Degludec Shows the Potential to Effectively Lower Blood Sugar, Including When Used Three Times a Week
2. Syndax Pharmaceuticals Entinostat Shows Clinical Promise in Patients with Advanced Hormone Refractory Breast Cancer
3. Highmark Study Shows Integrated Medical and Pharmacy Benefits Lower Costs, Promote Better Health
4. New Report Shows Record Number of Medicines Currently in Development to Treat Diabetes
5. Drug in New Class of Targeted Therapies Shows Early Promise Against Blood-Related Cancers
6. New Study Shows ENJUVIA® Significantly Reduced Sleep Time Awakenings Caused by Hot Flashes in Postmenopausal Women
7. Implanted Sleep Device Shows Promising Early Results
8. Data Shows Ambulance Fees Will Deter Emergency Calls for Help
9. New Study Shows 84 Percent Reduction in Post-Cesarean Section Infections Through Comprehensive Prevention Strategy
10. Novavaxs Seasonal Influenza VLP Vaccine Candidate Shows Positive Results in a Phase II Clinical Trial in Older Adults
11. Study Shows Superior Efficacy for TAXUS(R) Express(R) Stents at One Year Compared to Bare-Metal Stents in Diabetic Patients Experiencing Heart Attack
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/30/2014)... , Sept. 30, 2014 A study ... (OCT), offered a new look at the composition of ... how physicians understand and treat the disease, a leading ... at Baptist Health Lexington between September 2010 and May ... the Journal of the American College of Cardiology ...
(Date:9/30/2014)... , Sept. 30, 2014  HealthLoop® released an ... with HealthKit in iOS 8 and allows people to ... The app harnesses native iOS technologies to enhance the ... a robust connection with their doctors between visits. ... and the data they collect is exciting," says HealthLoop ...
(Date:9/30/2014)... Sept. 30, 2014  Georgia-Pacific Professional is a ... tissue for a wide range of away from ... product lines in healthcare, including hospitals, long-term care ... is introducing its healthcare products and solutions to ... the importance of infection control in the dental ...
Breaking Medicine Technology:New Imaging Tool May Allow Tailoring of Stroke Prevention to Each Patient 2HealthLoop Integrates with Apple's HealthKit Enabling Patients to Share Health Data with Their Doctors Right from their iPhone 2Georgia-Pacific Professional Brings Its Success in Medical Solutions to the Dental Community 2Georgia-Pacific Professional Brings Its Success in Medical Solutions to the Dental Community 3
(Date:9/30/2014)... EverStryke , the permanent match currently offered ... with a free book and class all about survival education ... an investigative review. , “Joe Marshall of SurvivalLife.com is ... preparation niche, and this product is an excellent way to ... products that Joe offers on his website to help people ...
(Date:9/30/2014)... 2014 VisitandCare.com reports that ... gone up more than 79 percent in 2014, marking ... also reported total revenue tripled for its entirety of ... professional strategy has allowed them to partner with ... patient comfort and privacy — with state-of-the-art surgical atmospheres ...
(Date:9/30/2014)... 2014 Regenerative Medicine Solutions (RMS) is ... in Nashville, Tennessee. RMS welcomes the launch of an ... expansion of a new treatment center for the Lung ... Apnea Institute to Nashville, the hope is to bring ... both diagnosed and undiagnosed. With Nashville being a hub ...
(Date:9/30/2014)... 30, 2014 Bifidobacteria, the primary bacteria ... poor diet, and stress, so a high Bifido probiotic ... of Ultimate Flora™ Men’s Complete contains 90 ... 7 Bifidobacteria strains to support a healthy large intestine ... up, and 32 billion cultures from 7 Lactobacillus strains ...
(Date:9/30/2014)... unprecedented, public-private partnership funded by the Department of ... development of better-run clinical trials and may lead ... injury, a condition affecting not only athletes and ... ranging from youngsters to elders. , Under ... a $17 million, five-year award from the DoD, ...
Breaking Medicine News(10 mins):Health News:EverStryke: Review Exposes Joe Marshall’s Permanent Match Survival Product 2Health News:VisitandCare.com Announces Record Demand for Plastic Surgery in Turkey 2Health News:VisitandCare.com Announces Record Demand for Plastic Surgery in Turkey 3Health News:VisitandCare.com Announces Record Demand for Plastic Surgery in Turkey 4Health News:Regenerative Medicine Solutions Expanding 2Health News:ReNew Life Introduces Ultimate Flora™ Men’s Complete Probiotic 90 Billion—Comprehensive Probiotic Support Just for Men 2Health News:US aims for traumatic brain injury clinical trial success 2Health News:US aims for traumatic brain injury clinical trial success 3Health News:US aims for traumatic brain injury clinical trial success 4
... of a complex signaling network in the developing brain ... congenital brain malformation, Yale School of Medicine researchers report ... variety of neurological disorders such as epilepsy, mental retardation, ... and genetic causes, but is most commonly due to ...
... is probing the link between breast density and its implication ... novel study on 1,112 women has brought to the fore, ... with dense breasts. The study revealed that, those with dense ... breast cancer, compared to women with fatty tissue in the ...
... of Vertebral Subluxation Research (JVSR), suggests that chiropractic ... from learning disabilities and dyslexia. ,The ... DC, president of the Swiss Chiropractic Pediatric Association, ... from learning and behavioral disorders. ,"This ...
... painkillers, especially the likes of Ibuprofen and Aspirin, which come ... out or exercise. A new study has suggested that the ... work out, may ease muscle pain by 50%. ... of kinesiology at the University of Georgia, Athens, 'A lot ...
... researchers who studied winners and nominees of the Nobel ... status and health in monkeys, but it has been ... status often brings more wealth, which improves living standards ... Scientist., ,Andrew Oswald and Matthew Rablen, economists at ...
... for chemotherapy which would have none of the unbearable side ... in the Canadian journal Cancer Cell. // ,The scientists ... DCA or the dichloroacetate which like a usual tablet can ... consumed. The greater advantage of DCA is its cost effectiveness ...
Cached Medicine News:Health News:Missing Molecule Has Important Role in a Developmental Brain Abnormality 2Health News:Chiropractic Care Helps Children With Learning Disorders and Dyslexia 2Health News:Chiropractic Care Helps Children With Learning Disorders and Dyslexia 3Health News:Work-outs, Not So Much of a ‘pain’ With Caffei 2
... experts say the most efficient,aspiration ... lateral movement of the,cannula tip. ... of,the ARC-H II Reciprocating Cannula,assures ... tip is,restricted to a longitudinal ...
Inquire...
... The Klein Pump provides optimum ... tumescent infiltration. Operates on any ... switch with safety Interlock and ... Spike Tubing, Double Spike Tubing, ...
... MicroAire Power Assisted Lipoplasty Device uses a 2-mm ... facilitate the movement of the cannula in tissue. ... with more fibrous tissue. That makes the lipoplasty ... will ease your mind to learn that the ...
Medicine Products: