Navigation Links
New Data Shows Blood Pressure Reduction Therapy with BENICAR(R) and BENICAR HCT(R) Effectively Reduces Blood Pressure in Elderly Patients to Target Blood Pressure
Date:5/8/2009

rsensitivity Reaction

Hypersensitivity reactions to hydrochlorothiazide may occur in patients with or without a history of allergy or bronchial asthma, but are more likely in patients with such a history.

Systemic Lupus Erythematosus

Thiazide diuretics have been reported to cause exacerbation or activation of systemic lupus erythematosus.

Lithium Interaction

Lithium generally should not be given with thiazides.

Adverse Events

  • The withdrawal rates due to adverse events (AEs) were similar with BENICAR(R) and BENICAR HCT(R) to placebo: BENICAR (2.4% vs 2.7%); BENICAR HCT (2.0% vs 2.0%)
  • The incidence of AEs with BENICAR and BENICAR HCT was similar to placebo

-- The only AE that occurred in >1% of patients treated with BENICAR(R) and more frequently than placebo was dizziness (3% vs 1%)

-- AEs reported in >2% of patients taking BENICAR HCT(R) and more frequently than placebo included nausea (3% vs 0%), hyperuricemia (4% vs 2%), dizziness (9% vs 2%), and upper respiratory tract infection (7% vs 0%)

Dosing and Administration

  • No initial dosage adjustments are recommended with BENICAR in elderly or in moderate to marked renal impairment*/hepatic dysfunction

-- In patients with possible depletion of intravascular volume (eg, patients on diuretics, particularly with impaired renal function), BENICAR should be initiated under close medical supervision and consideration given to use of a lower starting dose

  • For BENICAR HCT, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosage range

*Creatinine clearance <40 mL/min.

Please see full prescribing inform
'/>"/>

SOURCE Daiichi Sankyo, Inc.
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8

Related medicine technology :

1. Iomai Trial Shows 100 Percent Immune Response in Elderly Subjects Vaccinated With Novel Travelers Diarrhea Patch Vaccine
2. Study Shows Combination Therapy Incorporating AVODART(R) and Tamsulosin Provides Continuous Symptom Improvement Over 2 Years
3. Largest Study to Date Shows Significant Reductions in Risks of Blood Clots and Reintervention With CYPHER(R) Sirolimus-eluting Coronary Stent Compared to Taxus Stent
4. Kosans Second-Generation Hsp90 Inhibitor, Alvespimycin, Shows 42% Clinical Benefit in Phase 1 HER2-Positive Metastatic Breast Cancer Trial
5. Study Shows Plasma-Derived Human Thrombin Equivalent to Bovine Thrombin in Achieving Hemostasis in Surgery
6. Cleveland Clinic Study Shows the Diabetes Drug Pioglitazone Reduces Risk of Death, Heart Attack and Stroke, but Increases Risk of Heart Failure
7. New Data From Large Safety Analysis of MYCAMINE Shows Favorable Clinical Safety Profile
8. Feeling Anxious or Distracted? New Research Shows a Cup of Tea Could Help
9. New Study Shows Once-Monthly Boniva(R) is as Clinically Effective as Once-Weekly Fosamax(R) at Increasing Bone Mineral Density in Postmenopausal Women With Osteoporosis
10. Study Shows Vasopressin Receptor Antagonist VAPRISOL(R) (Conivaptan Hydrochloride Injection) Significantly Increased Serum Sodium Concentration in Patients with Euvolemic & Hypervolemic Hyponatremia
11. Newly Published Phase II Study Shows the Investigational Drug Vandetanib Prolongs Progression-Free Survival in Patients with Advanced Non-Small Cell Lung Cancer (NSCLC)
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/27/2015)... 27, 2015 Demonstrating the power of partnership ... LifeScience Alley  will produce a world class medical ... event, November 4-5, 2015, at the ... MN. This combined 2015 Minneapolis event is ... and business leaders all under one roof, offering a ...
(Date:4/27/2015)... YORK , April 27, 2015 Harwood ... against the board of directors of Aerie Pharmaceuticals, Inc. ... whether the board has breached its fiduciary duties to ... issued a press release announcing results from its first ... the press release disclosed that in the trial, Rhopressa ...
(Date:4/27/2015)... ALTO, Calif. , April 27, 2015  Eiger ... of Phase 2 data of lonafarnib in patients with ... from the LOWR HDV program, enrolled at Ankara University ... country where HDV is endemic. LOWR ... a parallel dose comparison study which randomized subjects to ...
Breaking Medicine Technology:LifeScience Alley and MD&M Minneapolis partner for Minnesota Medtech Week 2LifeScience Alley and MD&M Minneapolis partner for Minnesota Medtech Week 3Harwood Feffer LLP Announces Investigation of Aerie Pharmaceuticals, Inc. 2Eiger Bio Announces Interim Results of Lonafarnib in Combination with Ritonavir or Pegylated Interferon in Patients Infected with Hepatitis Delta Virus (HDV) 2Eiger Bio Announces Interim Results of Lonafarnib in Combination with Ritonavir or Pegylated Interferon in Patients Infected with Hepatitis Delta Virus (HDV) 3
... , CONCORD, Calif. , Feb. 3 Pulse ... of the Western United States . Effective February 1, 2010 , ... an exclusive sales territory encompassing the states of California (except for ... Oregon , Washington , Colorado , Utah , ...
... , HOUSTON and DALLAS , Feb. ... the company,s management, medical staff, and employees, are making multiple monetary and ... in Haiti . , In response to the magnitude 7.0 quake, ... and over 195,000 awaiting medical attention, First Choice owner Jack Novak ...
Cached Medicine Technology:Pulse Systems Announces New Sales Representation in the Western United States 2Pulse Systems Announces New Sales Representation in the Western United States 3First Choice ER to Donate Over $15,000 in Medical Supplies to Haitian Earthquake Victims 2
(Date:4/28/2015)... Colorado spine surgeon Donald Corenman, MD, ... popular spine education website NECKANDBACK.COM and his ... Media. This website has been redesigned to help patients ... spine, causes of neck and back pain, and conditions ... and personally answers questions in the neck and back ...
(Date:4/28/2015)... The buyer power score for ... indicating a medium level of buyer power in the ... equal power during negotiations. One factor helping buyer power ... health insurance policy from an insurance carrier (such as ... choose to self-fund their own policy or forgo insurance ...
(Date:4/28/2015)... It’s not all about the law at the Law ... litigation and plaintiff’s personal injury lawyer that has also served ... also about giving back to the community. This is ... Research Center Innovator’s Network. , “I believe there is a ... can and do good community-focused work in their communities,” said ...
(Date:4/28/2015)... SeniorCare.com has published the Misconception ... problem Americans have regarding aging and long-term care needs. ... services as they age, 63% of Americans do NOT ... the report, Carol Marak of SeniorCare.com interviewed 44 senior ... Care Association and The Scan Foundation. The experts discuss ...
(Date:4/28/2015)... Dead or damaged trees can quickly turn into ... cases, tree removal by a skilled team is recommended as ... , In their latest article , Precision Tree ... property owners today. Each method requires skill and expertise that ... , The article states that, “Tree removal is not “one ...
Breaking Medicine News(10 mins):Health News:Colorado Spine Surgeon Donald Corenman, MD, DC Launches Updated Version of NECKANDBACK.COM and Popular Back Pain Forum ASKSPINEDOC.COM 2Health News:Colorado Spine Surgeon Donald Corenman, MD, DC Launches Updated Version of NECKANDBACK.COM and Popular Back Pain Forum ASKSPINEDOC.COM 3Health News:New Data for Group Health Insurance Procurement Category Market Research Report from IBISWorld 2Health News:New Data for Group Health Insurance Procurement Category Market Research Report from IBISWorld 3Health News:New Data for Group Health Insurance Procurement Category Market Research Report from IBISWorld 4Health News:Seattle Attorney Paul Schneiderman Helping to Combat Cancer 2Health News:SeniorCare.com Report: America Has a Major Misconception on Aging 2Health News:Tree Removal Methods and Services Discussed in Recent Article by Precision Tree Services 2
... Jan. 28 Prime Companies, Inc. (Pink Sheets: PCIR) ... that will allow it to spin off its wholly ... 2007, to a San Diego firm which, once it ... 15 percent of the new company.The agreement with TransPacific ...
... Essential Hospital Guide to Get Your Loved One Out Alive," by ... Health Book of the Year by Allbooks Review Editor,s Choice Awards ... ... 2009 -- "Critical Conditions: The Essential Hospital Guide to Get Your ...
... of Health Strategies & Solutions, Inc the largest healthcare consultant in ... her expertise in management, governance, finance, operations and medical staff. ... ... The nation,s leading healthcare consulting firm, Health Strategies & ...
... A University of Rochester Medical Center study challenges common assumptions ... some people, surprisingly high levels remain in the body even ... suggests that BPA exposure may come from non-food sources, or ... journal Environmental Health Perspectives published the research online ...
... Jan. 27 Minnesotans with chronic,conditions and disabilities ... under the proposed budget of Gov. Tim Pawlenty, ... Center. , "As a ... thousands of Minnesotans following an illness, surgery or ...
... officials say company distributed ,adulterated, peanut butter products in ... -- The Georgia facility that produced the peanut butter ... in the past distributed questionable peanut butter product, U.S. ... 2008, Peanut Corporation of America, which owns the now-closed ...
Cached Medicine News:Health News:Prime Companies Reaches Agreement to Spin Off Subsidiary; Shareholders Gain 15 Percent Stake in New Telecommunications Company 2Health News:"Critical Conditions" Wins Best Health Book of the Year Awards 2Health News:New Employee of the Nations Largest Healthcare Consulting Firm 2Health News:Rochester study raises new questions about controversial plastics chemical 2Health News:Rochester study raises new questions about controversial plastics chemical 3Health News:Courage Center Experts Disagree With Gov. Pawlenty's Proposed Budget Cuts 2Health News:Courage Center Experts Disagree With Gov. Pawlenty's Proposed Budget Cuts 3Health News:Salmonella Outbreak Plant Shipped Dubious Product Before: U.S. Health Officials 2Health News:Salmonella Outbreak Plant Shipped Dubious Product Before: U.S. Health Officials 3
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: