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New Data Shows Blood Pressure Reduction Therapy with BENICAR(R) and BENICAR HCT(R) Effectively Reduces Blood Pressure in Elderly Patients to Target Blood Pressure
Date:5/8/2009

addition, 73 percent and 44 percent reached the ambulatory targets of <130/80 mm Hg and <120/80 mm Hg, respectively.

"The ability of Benicar(R) to bring elderly patients to blood pressure targets is very important, since attaining blood pressure targets can be so challenging in this group," said Dr. Joel M. Neutel, MD, director, Orange County Heart Institute and Research Center. "Although some physicians may be reluctant to use aggressive treatments for fear of an increased risk of adverse events, the findings show hypertension treatment can be accomplished safely and effectively in the elderly."

Benicar was well tolerated by elderly patients, with only nine of the initial 178 patients discontinuing treatment because of treatment emergent adverse events (AEs). In this trial, occurrence of drug-related AEs included: dizziness (3.4 percent), hypotension (2.2 percent), and/or headache (1.1 percent).

High blood pressure can cause permanent changes to blood vessels and the heart that may create serious problems elsewhere in the body.(4) Hypertension is one of the most prevalent conditions in the United States, affecting approximately one in three American adults (about 73 million people age 20 and older) and approximately one billion people worldwide.(5),(6) It is often difficult to control, and of those with high blood pressure, approximately 55 percent do not reach recommended BP levels.(7) The number of people with high blood pressure is expected to reach about 1.6 billion worldwide by 2025.(8)

Patients Older Than 75

A sub analysis of the trial found that 82.5 percent and 67.5 percent of patients over age 75 treated with BENICAR and BENICAR HCT(R) were able to achieve an ambulatory BP target of <135/85 and <130/80 mm Hg, respectively. Adverse events were also found to be similar for patients above and below 75 years of age.

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SOURCE Daiichi Sankyo, Inc.
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