Navigation Links
New Data Showed ACTOS(R) (pioglitazone HCl) Prevented Progression of Atherosclerotic Plaque Volume in Patients With Type 2 Diabetes
Date:3/31/2008

Data expands body of evidence in high risk population using IVUS, a unique

marker for coronary atherosclerosis

CHICAGO, March 31 /PRNewswire/ -- New data from a clinical trial using intravascular ultrasound (IVUS) technology found that in patients living with type 2 diabetes, ACTOS(R) (pioglitazone HCl) reduced the atherosclerotic burden in the coronary arteries compared to glimepiride, and prevented progression compared to baseline. These data stem from the PERISCOPE (Pioglitazone Effect on Regression of Intravascular Sonographic Coronary Obstruction Prospective Evaluation) trial.

The PERISCOPE trial was presented today as a late breaker at the 57th Annual Scientific Session of the American College of Cardiology in Chicago. This trial adds to the body of cardiovascular data for ACTOS. ACTOS studies, conducted over the past 10 years in more than 16,000 patients, including short- and long-term trials, as well as prospective and observational studies, have shown no evidence that ACTOS is associated with an increased risk of heart attack, stroke, or death.

"We are pleased with the results of the PERISCOPE, which further expands our cardiovascular data with ACTOS," said David P. Recker, M.D., senior vice president, Clinical Sciences and interim president at Takeda Global Research & Development. "While not definitive, data from PERISCOPE combined with results from a previous study, looking at surrogate endpoints, have shown a consistent trend toward decreasing cardiovascular risk by reducing the atherosclerotic burden in people with type 2 diabetes."

PERISCOPE is the first clinical trial to examine the effects of an oral antidiabetic medication on the development of coronary atherosclerosis in patients with type 2 diabetes using IVUS technology. The trial conducted in 97 centers in the U.S., Canada and Latin America with 543 patients, used IVUS imaging of the coronary arteries. The analysis demonstrated a statisticall
'/>"/>

SOURCE Takeda Global Research & Development Center, Inc.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. CASTLE Study Showed Similar Efficacy Between Once-Daily REYATAZ(R) (atazanavir sulfate)/ritonavir and Twice-Daily lopinavir/ritonavir at 48 Weeks in Previously Untreated HIV-Infected Adult Patients
2. New Study of Concerta(R) Showed Significant Improvement of ADHD Symptom Management in Adults Compared to Placebo
3. One Year Study of Exenatide Treatment Showed Improved Beta-Cell Function
4. One Year Study of Exenatide Treatment Showed Improved Beta-Cell Function
5. Data Presented at the American Heart Association Scientific Sessions 2007 Demonstrated Increased HDL with ACTOS(R) (pioglitazone HCl) Slowed the Progression of Carotid Intima-Media Thickness in Patients with Type 2 Diabetes
6. ACTOS(R) (pioglitazone HCl) Demonstrates Reduced Risk of Ischemic Cardiovascular Disease in Patients with Type 2 Diabetes
7. Early Research Suggests Umbilical Cord Blood Cell Therapy May Reduce Progression of Alzheimers Disease
8. Everolimus (RAD001) Significantly Extends Progression-Free Survival in Advanced Kidney Cancer Patients After Failure of Other Targeted Therapy
9. Update on Progression of Phosphagenics and Nestle Nutritions Phospha E(R) Trial
10. Phase II Study of Zevalin(R) Consolidation Following Fludarabine and Mitoxantrone Chemotherapy Results in 100 Percent Complete Remission Rate and 89 Percent Three-Year Progression Free Survival in Patients with Previously Untreated Non-Follicular Indolent
11. Zevalin(R) Combined With High-Dose Chemotherapy and Autologous Stem-Cell Transplantation (ASCT) Produces High Overall Survival and Progression-Free Survival Rates in Patients With Relapsed Non-Hodgkins Lymphoma
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/18/2014)...  Nopras Technologies ( www.nopras-tech.com ) has announced ... to the position of Director, Business Development – ... Bio-Investigations Ltd., a specialized global venture capital and ... ago, focused in the fields of human, veterinary, ... degrees in biology, biochemistry, and business from The ...
(Date:11/18/2014)... , Nov. 17, 2014   Headquartered in Anaheim, ... (OTC: GWPC) is a diversified company.  WholeHEALTH Products ... of advanced technology and proven expertise of its ... of health and wellness.  WholeHEALTH Products, comprehensive line ... clinics and healthcare centers, and 8 retail consumer ...
(Date:11/18/2014)... WARSAW, Ind. , Nov. 18, 2014  Zimmer ... that it has agreed with the European Commission (the ... of Zimmer,s proposed acquisition of Biomet by a limited ... with certain additional information. Deadline extensions ... been working closely with the regulatory authorities to facilitate ...
Breaking Medicine Technology:Nopras Technologies Inc. Appoints Director Of Business Development - East Coast Operations 2Nopras Technologies Inc. Appoints Director Of Business Development - East Coast Operations 3WholeHEALTH Product Inc. to File FDA Emergency Use Approval (EUA) for PCR Rapid Ebola Test 2Zimmer Provides Update on the European Commission Review Process Relating to the Pending Merger with Biomet, Inc. 2Zimmer Provides Update on the European Commission Review Process Relating to the Pending Merger with Biomet, Inc. 3Zimmer Provides Update on the European Commission Review Process Relating to the Pending Merger with Biomet, Inc. 4Zimmer Provides Update on the European Commission Review Process Relating to the Pending Merger with Biomet, Inc. 5
... SALT LAKE CITY, Nov. 17 ("WorldHeart"; Nasdaq: ... that it has finalized assignment and exclusive license agreements ... Mellon University (CMU), Pittsburgh, Pennsylvania for its next-generation minimally ... to provide partial cardiac support between 2-4 liters per ...
... Mich., Nov. 17 Bonovo Orthopedics, Inc., a leading ... government approval to market Pioneer,s full portfolio of spinal ... Chinese Orthopaedic Association annual meeting - the largest and ... and is planning a comprehensive rollout of Pioneer,s Quantum® ...
Cached Medicine Technology:WorldHeart Signs Agreements for Next-Generation Minimally Invasive Blood Pump 2WorldHeart Signs Agreements for Next-Generation Minimally Invasive Blood Pump 3Pioneer(R) Surgical Technology, Inc. and Bonovo(R) Orthopedics, Inc. Establish Foothold in Fastest Growing Spine Market in the World 2
(Date:11/18/2014)... Dennis Thompson HealthDay ... -- Daily low-dose aspirin therapy may not have significant ... The study, which involved more than 14,000 Japanese ... in heart-related deaths or non-fatal heart attacks and strokes ... "It indicates that primary prevention with daily ...
(Date:11/18/2014)... Dennis Thompson HealthDay ... Heart attack and stroke patients can safely take aspirin combined ... blood-thinning combination won,t increase a patient,s risk of early death, ... meeting of the American Heart Association in Chicago. The report ... . Analysis of data from more than a dozen ...
(Date:11/18/2014)... MONDAY, Nov. 17, 2014 (HealthDay News) -- Until recently, insect-transmitted ... America, but it has made its way to the United ... fatal illness is typically transmitted via the bite of the ... night. And now a new study suggests that common bedbugs ... bedbug can acquire and transmit the parasite. Our next step ...
(Date:11/17/2014)... Los Angeles, CA (PRWEB) November 17, 2014 ... revealed that thousands of patients throughout the country are ... feeling better than ever before. This is because the ... hormone therapy to their already impressive collection of prescription ... , Those who have incorporated Diet Doc’s best ...
(Date:11/17/2014)... World Food Processing announced today that ... American Farmer airing via RFD-TV 2nd QTR 2015. American ... RFD-TV. , World Food Processing is a sustainable solution ... unique system provides a secure system, supplying non-GMO and ... segment will educate viewers about World Food Processing’s unparalleled ...
Breaking Medicine News(10 mins):Health News:Daily Aspirin Fails to Help Older Hearts in Japanese Study 2Health News:Daily Aspirin Fails to Help Older Hearts in Japanese Study 3Health News:Long-Term Use of Aspirin Plus Blood Thinner Is Safe: Study 2Health News:Long-Term Use of Aspirin Plus Blood Thinner Is Safe: Study 3Health News:Bedbugs Could Be Potential New Source of Tropical Disease in U.S. 2Health News:Bedbugs Could Be Potential New Source of Tropical Disease in U.S. 3Health News:Best Anti-Aging Human Growth Hormone Therapy Safely and Naturally Restores Diet Doc Patients to More Youthful Levels 2Health News:Best Anti-Aging Human Growth Hormone Therapy Safely and Naturally Restores Diet Doc Patients to More Youthful Levels 3Health News:American Farmer to Feature World Food Processing in 2015 Series 2
... (Washington) - The American College of Physicians (ACP) today ... understands the serious financial constraints on the federal budget ... funding for discretionary programs that do not achieve sufficient ... a path towards reversing an unprecedented shortage of primary ...
... By Alan Mozes HealthDay Reporter , TUESDAY, ... overuse may be more common than thought among high ... sports, a new study finds. "The risk is ... are constantly trying to perfect their performance, and sometimes ...
... Agarwal, MD, the chief of surgical critical care at ... medicine at Boston University School of Medicine (BUSM), has ... (NTI) to identify optimal treatment methods for acute lung ... involves seven level one trauma centers and includes one ...
... Feb. 15, 2011 Breast-cancer patient Kristin Wiginton is ... with high-beam radiation using the Accuray CyberKnife System, which offers ... a shorter treatment period. Dr. Wiginton is among ... first of its kind in the Southwest investigating use ...
... that works in the "real world" may more ... based only on findings in clinical research settings, ... Heart Association,s cardiovascular disease prevention guidelines for women., ... have been primarily based on findings observed in ...
... By Jenifer Goodwin HealthDay Reporter , MONDAY, ... knee are robbing millions of older Americans of an average ... be feeling healthy and free of chronic pain, new research ... obese and/or have osteoarthritis of the knee, an often painful ...
Cached Medicine News:Health News:House leaders told some cuts in budget resolution could increase shortage of primary care physicians 2Health News:Stress Fractures Hitting High School Athletes 2Health News:Stress Fractures Hitting High School Athletes 3Health News:UT Southwestern launches clinical trial for treatment of breast cancer using CyberKnife 2Health News:UT Southwestern launches clinical trial for treatment of breast cancer using CyberKnife 3Health News:Updated heart disease prevention guidelines for women focus more on 'real-world' recommendations 2Health News:Updated heart disease prevention guidelines for women focus more on 'real-world' recommendations 3Health News:Obesity, Bum Knees Robbing Seniors of Good Years: Study 2Health News:Obesity, Bum Knees Robbing Seniors of Good Years: Study 3
The new XMI catheter incorporates the best in catheter technology to ,provide exceptional handling characteristics comparable to todays balloon catheters and stent delivery systems....
... XP Electroanatomical Mapping System combines the legendary ... operating ease of Windows* software. It ... powerful new tools that enhance your clinical ... you into the future of EP. ...
... 3085 temporary pacemaker is designed to be ... temporary atrial or ventricular or A-V sequential ... such pacing modes are indicated for therapeutic, ... 3085 can be used to measure atrial ...
Automated slide maker and stainer...
Medicine Products: