Navigation Links
New Data Show TORISEL Improves Progression-Free Survival for Patients With Relapsed/Refractory Mantle Cell Lymphoma
Date:5/31/2008

- Data From Phase 3 Study Presented at ASCO -

COLLEGEVILLE, Pa., May 31 /PRNewswire-FirstCall/ -- Wyeth Pharmaceuticals, a division of Wyeth (NYSE: WYE), today announced results of a three-arm phase 3 clinical trial that show patients with relapsed and/or refractory mantle cell lymphoma (MCL), a form of non-Hodgkin's lymphoma, treated with the mTOR (mammalian target of rapamycin) inhibitor TORISEL(R) (temsirolimus) experienced a statistically significant improvement in median progression-free survival (PFS), compared with single-agent therapy selected by the investigator (4.8 months vs. 1.9 months, P=0.0009). These results are being presented at the 44th Annual Meeting of the American Society of Clinical Oncology (ASCO) in Chicago.

"Relapsed/refractory mantle cell lymphoma is extremely difficult to treat, and this is the first comparative phase 3 study to show a significant improvement in progression-free survival for these patients," says Georg Hess, M.D., Johannes Gutenberg-Universitat, Mainz, Germany. "These data further support the antitumor activity seen in phase 2 studies of temsirolimus in relapsed/refractory mantle cell lymphoma and indicate that mTOR inhibition may be a viable approach in this disease area."

MCL accounts for approximately 6 percent of non-Hodgkin's lymphoma cases.

"These findings reinforce the clinical potential of mTOR inhibition with TORISEL. Wyeth is committed to the continued exploration of mTOR inhibition with TORISEL for the treatment of a variety of cancers," says Joseph S. Camardo, M.D., Senior Vice President, Global Medical Affairs, Wyeth Pharmaceuticals.

TORISEL was approved in May 2007 for the treatment of advanced renal cell carcinoma (RCC) and is the only
'/>"/>

SOURCE Wyeth Pharmaceuticals
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related medicine technology :

1. Wyeths Torisel and Roche/Genentechs Avastin Will Challenge Pfizers Sutent to Become the Clinical Gold Standard for Treatment of Metastatic Renal Cell Carcinoma
2. Wyeths TORISEL Receives European Commission Approval for the Treatment of Advanced Kidney Cancer
3. Wyeth Initiates INTORACT -- A New Clinical Trial to Examine TORISEL Plus Avastin for First-Line Treatment of Advanced Kidney Cancer
4. New Analyses Presented at ASCO Reaffirmed Efficacy and Safety of TORISEL in Patients With Advanced Kidney Cancer
5. Experimental Drug Ketasyn(TM) Improves Memory in Age-Associated Memory Impairment Study
6. First Osteoporosis Study in Hip Fracture Patients Finds Once-Yearly Reclast(R) Prevents Additional Fractures and Improves Survival
7. New England Journal of Medicine Study Shows ERBITUX(R) Improves Survival in Advanced Colorectal Cancer
8. TREANDA Significantly Improves Clinical Outcomes in Patients with Chronic Lymphocytic Leukemia Compared to Chlorambucil
9. New Approach to Treating Anthrax Significantly Improves Survival Rates in Pivotal Efficacy Studies
10. Oral Talactoferrin Alfa Improves Overall Survival in Patients With Refractory Non-Small Cell Lung Cancer: Final Phase 2 Study Results Presented at the 8th Annual Targeted Therapies for the Treatment Of Lung Cancer Meeting
11. Tailored Clopidogrel Dosing Improves PCI Outcomes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/1/2015)... September 1, 2015 BerGenBio AS ... announces that it has appointed Hilde Furberg ... to its Board of Directors, effective immediately. ... experience in pharma and biotech and is currently Senior ... company. Previously her role was Vice President and General ...
(Date:9/1/2015)... 1, 2015  Valeant Pharmaceuticals International, Inc. (NYSE: ... that its affiliate has entered into a collaboration ... an exclusive license to develop and commercialize brodalumab. ... monoclonal antibody in development for patients with moderate-to-severe ... Valeant will hold the exclusive rights to develop ...
(Date:8/31/2015)... PHOENIX , Aug. 31, 2015  DICOM ... announced today that it was recognized as a ... Radiology software.  The awards are sponsored ... and related professionals in the medical imaging industry.  ... for radiology professionals to acknowledge the contributions of ...
Breaking Medicine Technology:BerGenBio Appoints Non-Executive Directors 2Valeant And AstraZeneca To Partner On Brodalumab 2Valeant And AstraZeneca To Partner On Brodalumab 3Valeant And AstraZeneca To Partner On Brodalumab 4DG Suite Nabs "Minnies" Nomination for "Best New Radiology Software" 2
... 2012   Syndax Pharmaceuticals, Inc. and Ventana Medical ... an agreement to develop a companion diagnostic assay to ... treatment with erlotinib and Syndax,s proprietary lead molecule entinostat.  ... Ventana, a world leader and innovator of tissue-based diagnostic ...
... (Nasdaq: VRNM ), a leading industrial biotechnology ... enzymes, today announced the introduction of VEREFLOW™ alpha-amylase, a ... drilling operations.  This high performance enzyme effectively removes filter ... on the face of the wellbore, the hole drilled ...
Cached Medicine Technology:Syndax Pharmaceuticals Signs Agreement with Ventana Medical Systems, Inc. to Develop Companion Diagnostic Test for Entinostat 2Syndax Pharmaceuticals Signs Agreement with Ventana Medical Systems, Inc. to Develop Companion Diagnostic Test for Entinostat 3Syndax Pharmaceuticals Signs Agreement with Ventana Medical Systems, Inc. to Develop Companion Diagnostic Test for Entinostat 4Verenium Launches Second Enzyme Product for Oilfield Services 2Verenium Launches Second Enzyme Product for Oilfield Services 3
(Date:9/1/2015)... NV (PRWEB) , ... September 01, 2015 , ... ... or Self-Directed Care is, how to access caregivers and what to look for ... valuable and pertinent information. , Founded in 2006 in Canoga Park, CA by ...
(Date:9/1/2015)... ... September 01, 2015 , ... ... it has established the MAP Recovery Network, the Premier Outcomes-Driven Provider Network. ... This rapidly-growing alliance is dedicated to the provision of quality addiction treatment ...
(Date:9/1/2015)... ... September 01, 2015 , ... The integration ... patients directly from Practice Perfect to FOTO enabling cost and time savings, reducing ... , Steven Presement, President of Practice Perfect, stated "FOTO is a natural extension ...
(Date:9/1/2015)... ... ... Elizabeth Callahan, MD, founder and medical director of SkinSmart Dermatology® , ... filler treatment for volume loss in the hands. RADIESSE provides an immediate volumizing effect ... delivering smooth, natural-looking results that can last up to one year in most patients. ...
(Date:9/1/2015)... ... ... Routines… every family has them. Whether it’s a morning routine, meal time routine or ... too. Here are three reasons why routines can be beneficial for a child: , ... is implemented into a child’s schedule, they are able to anticipate what will happen ...
Breaking Medicine News(10 mins):Health News:AdvantagePlusCaregivers.com® Launches New Website for Corporate and Franchisee Locations in 3 States 2Health News:MAP Health Management Launches the MAP Recovery Network 2Health News:FOTO Announces New Integration Partnership with Practice Perfect 2Health News:SkinSmart Dermatology in Sarasota is Now Offering RADIESSE to Rejuvenate Hands 2Health News:SkinSmart Dermatology in Sarasota is Now Offering RADIESSE to Rejuvenate Hands 3Health News:Back into the Swing of Things: How Family Routines Benefit Children 2
... the 66th Annual Meeting of the American Academy ... ... AGI Dermatics presented,clinical research that indicates the 8-oxo-guanine DNA glycosylase (OGG1),encapsulated ... DNA repair, reducing MMP-1 secretion and increasing,collagen production in UV irradiated ...
... Uroplasty, Inc. (Amex:,UPI), a medical device company ... for the treatment of voiding dysfunction,announced today ... minimally invasive nerve stimulation device, designed for,office-based ... be,featured in three presentations at the Society ...
... Feb. 11 /PRNewswire-FirstCall/ - Neurochem Inc. (NASDAQ:,NRMX; TSX: ... 2008, Dr.,Francesco Bellini, Neurochem,s Chairman, President and Chief ... of the new,nutraceutical business, will present Neurochem,s strategy ... be held at the Waldorf-Astoria, in New York,(NY). ...
... bedside manner as better informed patients make ever-increasing demands ... in clinical decisions that directly affect their care. ... Related Research, Dr. J. Bohannon Mason of the Orthocarolina ... at the changes in society, the population and technology ...
... incidence of malignancy, so women with this condition can ... to a new study by a team of researchers ... A fibroadenoma is a benign growth of the breast ... usually associated with breast cancer, and are often diagnosed ...
... 2008 Researchers at Pulmonary Associates today announced ... for Emphysema) Trial, an international, multi-center clinical trial ... a new, minimally invasive option for those suffering ... airway bypass, a catheter-based bronchoscopic procedure designed to ...
Cached Medicine News:Health News:AGI Dermatics Data Indicates 8 Oxo-Guanine Repair Enzyme OGG1 Encapsulated in Liposomes, Reduces MMP-1, Increases Collagen and Enhances DNA Repair 2Health News:AGI Dermatics Data Indicates 8 Oxo-Guanine Repair Enzyme OGG1 Encapsulated in Liposomes, Reduces MMP-1, Increases Collagen and Enhances DNA Repair 3Health News:Studies on Urgent(R) PC to be Presented at the 2008 Society of Urologic Nurses and Associates Annual Symposium 2Health News:Neurochem to present at 2008 BIO CEO & Investor Conference - Presentation will be Web cast live 2Health News:Doctor who? Are patients making clinical decisions? 2Health News:Study finds patients with complex fibroadenomas can avoid surgery 2Health News:Researchers at Pulmonary Associates to study airway bypass procedure for severe emphysema 2
FLEXILOG spare part....
Complete calibration kits are available for both pH and manometry systems....
Flexilog custom medical carts are configured to suite the requirements of FLEXILOG motility system users. With locking wheels and storage drawers, our carts are suitable for any care provider in any ...
... kit for convenient pH catheter calibration., ,pH ... any procedure. The Alpine Calibration kit contains ... water for your convenience. Simply cut the ... catheters to soak. No measuring or pouring! ...
Medicine Products: