Navigation Links
New Data Show Patients With Chronic Low Back Pain Maintained Pain Reduction on Cymbalta(R)
Date:9/11/2009

ding to the International Association for the Study of Pain (IASP), the pain is an unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage.(3) Chronic pain is defined as pain that persists beyond acute pain or beyond the expected time for an injury to heal.(4) Men and women are equally affected by chronic low back pain, and it occurs most often between the ages of 30 and 50.(5)

Study Methods

Patients (N=181) with chronic low back pain (defined as low back pain present on most days for the preceding six months or longer) entered the study's 41-week extension phase and received duloxetine 60 mg or 120 mg once daily after completing a 13-week, placebo-controlled acute phase. Patients completing the acute phase on duloxetine remained on the same dose while those on placebo were switched to duloxetine. Maintenance of effect was assessed in 58 duloxetine patients who were responders [greater than or equal to 30 percent reduction in Brief Pain Inventory (BPI) average pain] at the end of the acute phase. If the upper bound of the 97.5 percent Confidence Interval (CI) of the mean change from the end of the acute phase for the BPI average pain was less than the pre-specified margin of 1.5, then maintenance of effect was established.

About Cymbalta

Serotonin and norepinephrine in the brain and spinal cord are believed to both mediate core mood symptoms and help regulate the perception of pain. Based on preclinical studies, Cymbalta is a balanced and potent reuptake inhibitor of serotonin and norepinephrine that is believed to potentiate the activity of these chemicals in the central nervous system (brain and spinal cord). While the mechanism of action of Cymbalta is not known in humans, scientists believe its effects on depression and anxiety symptoms, as well as its effect on pain perception, may be due to increasing the activity o
'/>"/>

SOURCE Eli Lilly and Company
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related medicine technology :

1. Yoga Benefits Back-Pain Patients
2. Two-Year SYNTAX Data Show Comparable Safety Outcomes for Complex Patients Treated With TAXUS(R) EXPRESS(R) Stents and Bypass Surgery
3. CRESTOR(R) Reduced Risk of Cardiovascular Events in Elderly Patients in New Analysis of Jupiter
4. New Large-Scale, Global Study Provides Additional Information About an Intensified Dose-Regimen of PLAVIX(R) in Acute Coronary Syndrome Patients Undergoing Angioplasty
5. Cardium Reports Non-Healing Wounds Continue to Challenge Patients and Healthcare Providers
6. Lurasidone Demonstrated Efficacy in Treating Patients With Schizophrenia in Pivotal Phase 3 Study
7. Amgen Announces Top-Line Results of Trial to Reduce Cardiovascular Events With Aranesp(R) Therapy (TREAT) in CKD Patients With Type-2 Diabetes
8. US FDA Approves Extavia(R) - the First in a New Portfolio of Planned MS Therapies from Novartis to Help Patients with this Devastating Disease
9. ANA773 Demonstrates Significant Antiviral Response in Early Clinical Trial in Hepatitis C Patients
10. Amgen Announces Positive Top-Line Results for Denosumab in Trial for Delay of Skeletal Related Events in Bone Metastases Patients Compared to Zometa(R)
11. Telik Announces Publication of Positive Phase 1 Results of a Multicenter Study of Ezatiostat Hydrochloride (TELINTRA(R), TLK199) Tablets In Patients With Myelodysplastic Syndrome
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/28/2015)... , Aug. 28, 2015 , ... Dr. Ra from Biostar , Published in ,Stem ... increase of lifespan through multiple IV administration of Adipose-derived ... and life expectancy found , Commercialization within 5 ... determined the possibility that adult mesenchymal stem cells (MSCs) ...
(Date:8/28/2015)... -- The global mHealth market ... 2020, growing at a CAGR of 47.6% from 2013 ... View Research, Inc. Monitoring services is expected to grow ... 2020.      (Logo: http://photos.prnewswire.com/prnh/20150105/723757 ) , ... of chronic diseases such as cancer, heart ailments, and ...
(Date:8/27/2015)... WASHINGTON , Aug. 27, 2015 ... Collaborative (BPC) applauds the U.S. Food and Drug ... a distinguishable name in its draft guidance issued ... of biological products proposes distinguishable names, calling for ... includes an FDA-designated suffix. This proposal reflects the ...
Breaking Medicine Technology:Korean Researchers Find the Possibility that Adult Mesenchymal Stem Cells (MSCs) May Extend Lifespan 2mHealth Market is Expected to Reach $49.12 Billion By 2020: Grand View Research, Inc. 2mHealth Market is Expected to Reach $49.12 Billion By 2020: Grand View Research, Inc. 3mHealth Market is Expected to Reach $49.12 Billion By 2020: Grand View Research, Inc. 4mHealth Market is Expected to Reach $49.12 Billion By 2020: Grand View Research, Inc. 5Biologics Prescribers Collaborative (BPC) Statement on FDA Draft Guidance entitled "Nonproprietary Naming of Biological Products" 2
... Dec. 5, 2011  At this week,s 46th Annual Midyear ... Health-System Pharmacists (ASHP), Cardinal Health launched BarCode360™ , ... making it easier, more timely and cost efficient to ... scanned at the patient bedside. ASHP has ...
... Pharmaceutical Co. Ltd, in which European healthcare venture capital ... as one of the Deloitte & Touche,s 50 top-performing ... the past three years. Beijing-headquartered GC-Rise, which ... revenues rising more than 270% on average per annum ...
Cached Medicine Technology:Cardinal Health Launches Innovative Barcode Administration Solution to Help Hospitals Bridge Gaps in Medication Safety 2Cardinal Health Launches Innovative Barcode Administration Solution to Help Hospitals Bridge Gaps in Medication Safety 3Women Health Expert GC-Rise Listed in Deloitte's 50 Top-performing Companies 2
(Date:8/28/2015)... ... August 28, 2015 , ... ... for its adolescent residential, counseling, day treatment and intensive family based services. , ... standards for quality and its pursuit of excellence. As a nonprofit charity for ...
(Date:8/28/2015)... ... August 28, 2015 , ... ... at a low cost. Personalized with practice contact information and logos, Calendars stand ... offices can also incorporate Calendars into seasonal mailings, thank you and welcome communications, ...
(Date:8/28/2015)... ... ... Northridge dentists Dr. Elyson and Dr. Assili are now offering patients ... a one hour treatment of this teeth whitening option. Zoom whitening is ... features that can turn teeth up to nine shades whiter. Effective on a wide ...
(Date:8/28/2015)... ... August 28, 2015 , ... SharkNinja, an ... coffee connoisseur and Emmy-nominated actress, Sofia Vergara, and unveil the Ninja® brand’s ... Extraction™ technology, which delivers a variety of sizes and styles while achieving the ...
(Date:8/28/2015)... , ... August 28, 2015 , ... ... is dedicated to distributing health information technology innovation to transform quality and efficiency ... of the survey will be de-identified and aggregated before being publicly shared to ...
Breaking Medicine News(10 mins):Health News:West Ridge Academy Awarded CARF Three-Year Accrediation 2Health News:SmartPractice® Introduces 2016 Calendars for Dental Practice Giveaways 2Health News:Northridge Dentists Dr. Elyson and Dr. Assili Now Offer a Special Promotion on Zoom Teeth Whitening 2Health News:Sofia Vergara Partners With SharkNinja® To Launch The Ninja Coffee Bar™ 2Health News:Sofia Vergara Partners With SharkNinja® To Launch The Ninja Coffee Bar™ 3Health News:WEDI's The Sullivan Institute for Healthcare Innovation Releases Gaps in Care Survey 2
... Acute Myelogenous Leukemia (AML) and those experiencing bone marrow ... transplantation graft failure or engraftment delay,- Bayer will replace current ... supplies of Leukine to current levels as ... HealthCare Pharmaceuticals,Inc. announced today, following consultation with the United States ...
... 23 InterMune, Inc.,(Nasdaq: ITMN ) today announced ... will present at the 2008 Wachovia Healthcare,Conference in Boston ... To access a live audio webcast of the presentation, ... investor relations page of InterMune,s,corporate website at http://www.intermune.com ...
... Year-Round Campaign Continues to Benefit the National Breast ... ... to underbanked,customers, demonstrated desire to adopt and contribute to a cause, ... United,States, and ACE Cash Express, a leading retailer of financial services,have ...
... Alice S. Fisher of the Criminal Division and ... of Florida announced today that,owners of nine separate ... terms within the past two weeks. Collectively, the ... worth of,unnecessary durable medical equipment (DME) and infusion ...
... interdisciplinary team reports the design of chimeric ... for potential application in biomedical research. , ... stage where domains that traditionally belonged to ... are coming together to offer new synergistic ...
... Fewer deaths, heart attacks found in 18-month study , , WEDNESDAY, ... risk of death and heart attacks than stents for people ... study indicates. , The finding is far from the last ... author Dr. Edward L. Hannan, associate dean for research at ...
Cached Medicine News:Health News:Bayer Establishes US Special Access Program for Leukine(R) While Replacing Current Liquid Formulation 2Health News:Bayer Establishes US Special Access Program for Leukine(R) While Replacing Current Liquid Formulation 3Health News:Bayer Establishes US Special Access Program for Leukine(R) While Replacing Current Liquid Formulation 4Health News:InterMune to Present at the 2008 Wachovia Healthcare Conference 2Health News:NetSpend(R) and ACE Cash Express Customers Keep Thinking Pink With the All-Access(R) Visa(R) Prepaid Card Program 2Health News:NetSpend(R) and ACE Cash Express Customers Keep Thinking Pink With the All-Access(R) Visa(R) Prepaid Card Program 3Health News:NetSpend(R) and ACE Cash Express Customers Keep Thinking Pink With the All-Access(R) Visa(R) Prepaid Card Program 4Health News:Nine Miami Defendants in Strike Force Cases Sentenced for $56.5 Million in Medicare Fraud 2Health News:Nine Miami Defendants in Strike Force Cases Sentenced for $56.5 Million in Medicare Fraud 3Health News:Nine Miami Defendants in Strike Force Cases Sentenced for $56.5 Million in Medicare Fraud 4Health News:Engineering chimeric polypeptides to illuminate cellular redox states 2Health News:Surgery Better Than Stents for Multiple Blockages 2Health News:Surgery Better Than Stents for Multiple Blockages 3
... remarkable anti-reflux valve is enclosed ... which prevents the valve from ... in sitting or reclining positions. ... and interference free ensuring uninterrupted ...
... anti-reflux valve is enclosed in ... prevents the valve from being ... sitting or reclining positions. The ... interference free ensuring uninterrupted flow ...
... valve is enclosed in a ... the valve from being accidentally ... or reclining positions. The valve ... free ensuring uninterrupted flow and ...
Intermittent catheter - SpeediCath™ is pre-hydrated and ready to use right out of the package. Just open, cath and get on with your life....
Medicine Products: