Navigation Links
New Data Show In Vitro Potency of Doripenem Against Resistant Bacteria
Date:10/27/2008

icrograms/mL, and 4 micrograms/mL, respectively.

Additionally, the study examined the incidence of ESBLE and CIPRE in baseline Enterobacteriaceae isolates in North America (NA), South America (SA), and Europe (EU). To evaluate these levels, minimum inhibitory concentrations (MICs) were determined for ESBLE and CIPRE. ESBLE were determined as Enterobacteriaceae that included Escherichia coli, Klebsiella spp., and Proteus spp. with ceftazidime MICs greater than or equal to 2 micrograms/mL. CIPRE were defined as Enterobacteriaceae with ciprofloxacin MIC greater than or equal to 4 micrograms/mL. The study results showed:

-- Relative incidence of ESBLE was highest in Europe (8% of all

Enterobacteriaceae), and the relative incidence of CIPRE was highest in

South America (16%).

-- In ESBLE from all regions combined, 68% were resistant to ciprofloxacin,

while 98% had doripenem MICs less than or equal to 2 micrograms/mL.

-- In CIPRE from all regions combined, 99% had carbapenem MICs less than or

equal to 4 micrograms/mL.

A second study, also presented at the 2008 ICAAC/IDSA Joint Meeting, that examined stored clinical Enterobacteriaceae isolates, found that overall susceptibility (less than or equal to 0.5 micrograms/mL) for doripenem among Enterobacteriaceae strains were 98.9% and 96.5% for strains expressing ESBL and AmpC Beta-lactamase enzymes, respectively. Both ESBL and AmpC Beta-lactamase are enzymes that destroy cephalosporins and other related antibiotics. Approximately, 32,990 Enterobacteriaceae isolates in four geographic locations (North America, Latin America, Europe and Asia-Pacific) were recovered from more than 60 medical centers, which participated in the global doripenem surveillance program from 2003 to 2007.

In this study, susceptibility testing was performed by the monitoring laboratory using Clinical and Laboratory Standards Institute (CLSI) methods and interpretive c
'/>"/>

SOURCE Johnson & Johnson Pharmaceutical Research & Development,L.L.C.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Georgia Reproductive Specialists Participates in Largest-Ever In Vitro Fertilization Clinical Trial in the World
2. Oritavancin Demonstrates Superior In Vitro Activity to Vancomycin and Metronidazole Against C. Difficile Bacteria
3. Targanta Presents First Data Demonstrating In Vitro Activity and In Vivo Efficacy of Prodrugs in Osteomyelitis Models
4. Oritavancin Demonstrates Potent and Rapid In Vitro Activity Against MRSA, VRE and Other Strains of Resistant Bacteria
5. MatTeks EpiDerm In Vitro Tissues Headed for Validation in Europe
6. Sequoia Pharmaceuticals Presents In Vitro and First-in-Human Data Supporting Further Development of SPI-256, a Novel Investigational Protease Inhibitor
7. Dendreon Presents Data Correlating the Cumulative Potency of PROVENGE(R) to Overall Survival
8. New Data Show Doripenem as Effective as Commonly Used Therapies in Treating Hospital-Acquired Pneumonias
9. Vical Begins Phase 1 Trial of DNA Vaccine Against H5N1 Pandemic Influenza
10. Molnlycke Drives Home the Fight Against Staph and Other MRSA Infections
11. Mayo Clinic Study Finds FDA Warning Against Anti-Nausea Drug Droperidol Unnecessary
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/29/2014)... , Aug. 29, 2014  BC Technical, the ... acquired Polaris Medical Imaging, a leader in sales, service ... strategic acquisition allows BC Technical to continue to expand ... within MR and CT modalities. "We ... said Mark Alvarez , president and CEO of ...
(Date:8/29/2014)... Research and Markets  has announced the addition of the ... to their offering. The Central Nervous System ... segments of pharmaceuticals industry. The numbers of CNS disorders have ... unable to meet the market requirements. There has been steady ... over the past two decades. The market for CNS therapies ...
(Date:8/29/2014)... Research and Markets has announced ... Forecast of Pharmaceutical Equipment Market in China, 2014-2018" ... Development Trend Forecast of Pharmaceutical Equipment Market in ... China,s pharmaceutical equipment industry in the aspects ... and business performance of domestic major enterprises, as well ...
Breaking Medicine Technology:BC Technical Acquires Polaris Medical Imaging 2US CNS Disorders Drug Pipeline Insight 2014 2Research and Development Trend Forecast of Pharmaceutical Equipment Market in China, 2014-2018 2
... ABBOTT PARK, Ill., April 21 Abbott (NYSE: ... strengthening its pharmaceutical pipeline in immunology and oncology. , ... The acquisition provides Abbott with ... that complement its existing diverse oncology program.  The new Abbott compounds ...
... Magellan Biosciences, Inc., an emerging leader in clinical ... first to offer minocycline and telavancin on IVD-labeled microbroth ... (FDA) has cleared TREK-brand Sensititre MIC plates for testing ... as well as telavancin against Gram positive bacterial isolates ...
Cached Medicine Technology:Abbott Completes Acquisition of Facet Biotech 2FDA Clears Three Additional Antimicrobials for Use on TREK Sensititre(R) In Vitro Diagnostic (IVD) MIC Susceptibility Plates: Minocycline and Telavancin Used to Treat MRSA and Other Infections; and Tigecycline, Now Cleared for Streptococcus Pneumoni 2FDA Clears Three Additional Antimicrobials for Use on TREK Sensititre(R) In Vitro Diagnostic (IVD) MIC Susceptibility Plates: Minocycline and Telavancin Used to Treat MRSA and Other Infections; and Tigecycline, Now Cleared for Streptococcus Pneumoni 3FDA Clears Three Additional Antimicrobials for Use on TREK Sensititre(R) In Vitro Diagnostic (IVD) MIC Susceptibility Plates: Minocycline and Telavancin Used to Treat MRSA and Other Infections; and Tigecycline, Now Cleared for Streptococcus Pneumoni 4
(Date:9/2/2014)... Smile Squared, a well-known Buy One, Give One company, ... toothbrush. For every toothbrush purchased, Smile Squared gives one ... created by my wife and me after volunteering at ... of Smile Squared. “There, we saw children who had ... the same children didn't own a toothbrush. We wanted ...
(Date:9/2/2014)... Tuesday 2 September 2014: Health structures explain nearly ... according to the results of a joint ESC-OECD ... Aldo Maggioni. Clinical variables explained more than 80% ... a unique evaluation which combines clinical data and ... a fuller picture of the reasons some patients ...
(Date:9/2/2014)... Aeroflow Healthcare, an industry leader and ... the opening of its new office to be located ... Business Parkway, Suite D, Greer, SC 29651. This new ... a more convenient location in the Greenville area. , ... the physicians, hospitals and patients we serve, to ensure ...
(Date:9/2/2014)... FL (PRWEB) September 02, 2014 ... for about a decade, primarily to help people ... time, there are three developed systems,” says Dana ... approaches substantively differ, the goals are much the ... support of some type of harmonica.” , The ...
(Date:9/2/2014)... During the fall season, before the ... winter months to prevent costly damage later on. Pasquali ... company, suggests these fall preventative home maintenance tips. , ... throughout fall to prevent build up of leaves and ... problems, pest infestations, wet basements, foundation damage and many ...
Breaking Medicine News(10 mins):Health News:Smile Squared's Colorful Buy One, Give One Toothbrush Now Available in Schnucks Stores 2Health News:Health structures explain nearly 20 percent of non-adherence to heart failure guidelines 2Health News:Aeroflow Healthcare Opens Office In Greer, SC To Service Greenville & Spartanburg Patients 2Health News:Harmonica Techs, Inventor of the Pulmonica Pulmonary Harmonica, Outlines New Uses for Harmonicas in Healthcare 2Health News:Harmonica Techs, Inventor of the Pulmonica Pulmonary Harmonica, Outlines New Uses for Harmonicas in Healthcare 3Health News:Northern Virginia Real Estate Company Pasquali Realty Group Suggests These Maintenance Tips for Homeowners This Fall 2
... Largest Increase In Hispanics, Up 18%, New ASPS Plastic ... Tough economic times may have caused ... procedures among ethnic patients are up. According to statistics ... (ASPS), ethnic cosmetic procedures increased 11 percent in 2008, ...
... March 25 An amazing medical discovery that provides ... is in the US and looking to make the ... Release, go to: http://www.prnewswire.com/mnr/bathmateus/37601/ Developed by engineers, originally ... US at www.bathmateus.com , the Bathmate Hydropump reverses ...
... and Accountability Act (HIPAA) consists of a quick glance ... by signing a form stating that we have reviewed ... law that was enacted by Congress to promote health ... protecting the confidentiality, integrity and availability of the information. ...
... heart disease should avoid consuming energy drinks, according to a ... the Annals of Pharmacotherapy . , Researchers found ... a popular energy drink experienced an increase in their blood ... were reported. , The increases in blood pressure and heart ...
... for America,s Health (TFAH) and the Robert Wood Johnson ... America,s Food Safe: A Blueprint for Fixing the Food ... Human Services , which examines problems with the fragmented ... the food safety functions at the U.S. Department of ...
... March 25 Letter Carriers union President William H. Young ... U.S. Postal Service, endangered by the greed and recklessness of ... enacts bipartisan legislation that would save the Postal Service billions ... are not here today to ask for a taxpayer bailout, ...
Cached Medicine News:Health News:Video: Cosmetic Procedures Up In All Ethnic Groups Except Caucasians In 2008 2Health News:Video: Bathmate Hydropump Poised to Replace Cialis, Levitra, and Viagra 2Health News:Conference on safeguarding health information, May 18-19 2Health News:Energy drinks may be harmful to people with hypertension, heart disease 2Health News:New Report Calls Food Safety System Antiquated, Calls for Reform 2Health News:New Report Calls Food Safety System Antiquated, Calls for Reform 3Health News:New Report Calls Food Safety System Antiquated, Calls for Reform 4Health News:Young Tells Congress Survival of Postal Service Could Depend on Passage of Relief Legislation 2
Liquichek Whole Blood Volatiles Control is an assayed liquid control for monitoring volatile compounds. This product is available in 2 levels....
qUAntify Control is designed to monitor the performance of urine dipstick testing. The control is available in 12 mL ready-to-use dropper bottles....
Lyphochek Urine Bone Markers Control is a bilevel human urine based control designed to monitor tests for urinary markers of osteoporosis management and bone resorption....
Lyphochek Tumor Marker Control is a comprehensive, bilevel product designed to assess the performance of various cancer antigen tests, including esoteric tumor markers....
Medicine Products: