Navigation Links
New Data Show High Frequency of Medical Claims for Gastrointestinal Events by Patients on Antiplatelet Therapy
Date:5/6/2008

et medicines such as clopidogrel or aspirin, and an even higher risk for patients taking clopidogrel in combination with aspirin or other non-steroidal anti-inflammatory drugs (NSAIDS). One study showed that treatment with clopidogrel augmented bleeding caused by NSAIDS, an effect attributed to the inhibition of platelets by clopidogrel.

Increasing age is a recognized risk factor for ulcer disease, and clopidogrel is commonly prescribed for elderly patients with atherosclerosis. In the insurance claim review, 72 percent of patients were over 60 years of age. Information about concurrent aspirin use, which is common among patients with cardiovascular disease and particularly among clopidogrel users, was not available. A higher incidence of bleeding side effects was seen in women -- 7.2 percent filed medical claims for an ulcer or gastrointestinal bleeding while 5.4 percent of men filed claims.

"The surprisingly high frequency of these claims raises a significant public health concern," said Dr. Byron Cryer, the John C. Vanatta III Professor of Medicine and Associate Dean for Minority Affairs at Southwestern Medical School in Dallas. "Until recently, gastrointestinal side effects in patients taking antiplatelet therapy have been largely underappreciated by physicians, who are appropriately focused on preventing future heart attacks. We need to address this problem to help keep patients on their medical treatment regimens."

Dr. Cryer is a member of the Scientific Steering Committee overseeing COGENT, the global Phase 3 clinical trial program sponsored by Cogentus. The COGENT program will evaluate the efficacy and safety of Cogentus's lead product, CGT-2168, which combines clopidogrel and the gastroprotectant omeprazole. CGT-2168 is designed to maintain the cardiovascular benefits of antiplatelet therapy while reducing its potentially serious gastrointestinal side effects.

ABOUT COGENTUS

Cogentus Pharmaceuticals, Inc., of Menlo Park, C
'/>"/>

SOURCE Cogentus Pharmaceuticals, Inc.
Copyright©2008 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2 3

Related medicine technology :

1. New Data Reveal Topical Divigel(R) (estradiol gel) 0.1% Significantly Reduces Frequency and Severity of Hot Flashes
2. Quantum Immunologics, Inc. and the South Alabama Medical Science Foundation Announce an Early Clinical Evaluation of a Novel Immuno-therapeutic Vaccine for Treating Advanced Human Breast Carcinomas
3. Delcath Expands Phase III Trial for Metastatic Melanoma to Include University of Maryland Medical Center
4. Tepha Announces First Human Usage of Medical Devices Derived from New Class of Resorbable Polymers
5. Rib-X Pharmaceuticals Renews Collaborative Agreement with the Medical Research Council
6. Nektar Therapeutics to Present Positive Data at Upcoming Medical and Scientific Meetings
7. Columbia University Medical Center and Rosetta Genomics Announce Columbia Universitys Submission of the First Cancer Diagnostic Test Based on Rosetta Genomics Proprietary MicroRNA Technology for Approval to the New York State Department of Health Clinica
8. Orqis(R) Medicals Cancion(R) System Significantly Increases Cardiac Performance
9. New York-Presbyterian/Weill Cornell is First New York Medical Center to Offer Tantalus Clinical Trial to Diabetes Patients
10. Stem Cell Research Provides Medical Breakthrough to Repair Heart Cell Damage Created by a Heart Attack
11. Valor Medical Announces First Human Implant of Neucrylate AN(TM) for Treatment of Cerebral Aneurysm
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/15/2009)... At today,s regular meeting of the board ... LZ ), the board declared a regular quarterly dividend ... to holders of record at the close of business ... Corporation ,, The Lubrizol Corporation (NYSE: ... produces and supplies technologies that improve the quality and ...
(Date:12/15/2009)... Dec. 15 NxStage Medical, Inc. (Nasdaq: ... dialysis products, today announced that a group of ... be embarking on a week-long, conventional (non-dialysis) Caribbean ... The cruise, dubbed the "2010 Freedom Cruise: We,re ... Fla. on January 3, 2010 and returns on ...
(Date:12/15/2009)... Dec. 15 Varian Medical Systems (NYSE: ... results for first quarter of fiscal year 2010 following ... 2010. The news release will be followed by ... p.m. PT. The news release and a link ... the company website at: www.varian.com/investor . To ...
Breaking Medicine Technology:Lubrizol Declares Dividend 2Group of NxStage(R) Home Hemodialysis Patients to Take Caribbean Cruise with the System One(TM) 2Group of NxStage(R) Home Hemodialysis Patients to Take Caribbean Cruise with the System One(TM) 3Group of NxStage(R) Home Hemodialysis Patients to Take Caribbean Cruise with the System One(TM) 4Varian Medical Systems Schedules First Quarter FY2010 News Release and Conference Call 2Oxygen Biotherapeutics Inc Expands Board of Directors 14593 1Oxygen Biotherapeutics Inc Expands Board of Directors 14593 2Transdel Pharmaceuticals to Webcast Presentation at 4th Annual BIOCOM Investor Conference 5691 1Transdel Pharmaceuticals to Webcast Presentation at 4th Annual BIOCOM Investor Conference 5691 2Transdel Pharmaceuticals to Webcast Presentation at 4th Annual BIOCOM Investor Conference 5691 3AMD LASERS Announces Partnerships With Three Industry Leading Companies 5686 1
(Date:12/15/2009)... WASHINGTON, Dec. 15 Our Lady of Lourdes ... New Jersey hospitals, has agreed to pay the United ... defrauded Medicare, the Justice Department announced today. The two ... in Camden, N.J., and Lourdes Medical Center of Burlington ... a defendant in a suit brought by a whistleblower, ...
(Date:12/15/2009)... for protection, CDC says, , , TUESDAY, Dec. 15 (HealthDay ... flu vaccine have been recalled by manufacturer Sanofi Pasteur ... officials said Tuesday. , According to the U.S. Centers ... of the vaccine for children aged 6 months to ... than required potency levels. "This means that doses from ...
(Date:12/15/2009)... Pa., Dec. 15 4R Systems, Inc., ... chain solutions which help retailers significantly increase profits ... decisions, announced today that The Vitamin Shoppe has ... ,, "4R,s store and DC inventory solutions have ... efficiency and in-stocks over the last two years," ...
(Date:12/15/2009)... 15 North American application activity for ... year-over-year, according to the MIB Life Index(SM) ... over the past three months have lifted year-to-date ... -1.6%, to flat at November,s close, -0.1%. ... in the benefits available from life insurance," says ...
(Date:12/15/2009)... decade, the United Nations Foundation has led the fight ... World Malaria Report 2009 that the global strategies for ending malaria ... Health for the United Nations Foundation , ... Washington, ... United Nations Foundation has led the fight against malaria, ...
Breaking Medicine News(10 mins):Health News:Parent Company of Two New Jersey Hospitals to Pay U.S. $7.95 Million to Settle False Claims Act Allegations 2Health News:Large Recall of Children's Swine Flu Vaccine 2Health News:4R's Profit Optimizing Inventory Solutions Helps The Vitamin Shoppe Drive Increased Productivity and Performance 2Health News:4R's Profit Optimizing Inventory Solutions Helps The Vitamin Shoppe Drive Increased Productivity and Performance 3Health News:4R's Profit Optimizing Inventory Solutions Helps The Vitamin Shoppe Drive Increased Productivity and Performance 4Health News:MIB Life Index Reports North American Life Insurance Activity Up 3.9% in November 2Health News:MIB Life Index Reports North American Life Insurance Activity Up 3.9% in November 3Health News:Statement by Dr. Daniel Carucci, Vice President for Global Health for the United Nations Foundation, on Progress Shown in World Malaria Report 2009 2
... in Scotland is the only bird to have shown the H5N1 ... identified with the infection and health // officials are now confident ... species. This has calmed fears of a pandemic in the country. ... were unaware of where exactly the bird came from, but say ...
... have revealed smuggled bird and poultry parts or in whole.// ... found bags of duck feet. Also a similar raid at a ... chicken meat smuggled from China. ,According to experts there is ... including live birds, chicks and meat — is helping spread bird ...
... first face transplant, and the second such operation in the ... hospital in Xi'an replaced two-thirds of the face of 30-year-old ... two years ago, Zhang Yingzhi, the president of the hospital, ... complex than the first face transplant in France in November ...
... those mentioned on kid’s books could be a great way ... by Dr. Deborah Strevy, an education expert. ,Although ... for over thousands of years, most of us do not ... can be attributed to busy lifestyle. Extended conversations among family ...
... was considered out of fashion for years, is back in Germany. ... in touch with fashion are growing// beards again, much to the ... author Mercedes Bunz was one of the first to notice the ... US. She said she was shocked to see men in their ...
... others think of us and to what extent their perception ... this//, in the latest issue of Current Directions in Psychological ... what people do and the manner in which their feelings ... a strong pull on an individual’s thought process. ,Infact, ...
Other Medicine News:Health News:Smuggling could also be a carrier to bird flu spread. 2Health News:Beards Are Back In Germany With A Bang! 2
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
Medicine Products: