Navigation Links
New Data Show Ceftobiprole as Effective as Combination Therapy in Treating Patients with Diabetic Foot Infections
Date:10/8/2007

RARITAN, N.J., Oct. 8 /PRNewswire/ -- Johnson & Johnson Pharmaceutical Research & Development, L.L.C. today announced results from a Phase III trial that showed that investigational antibiotic ceftobiprole was found to clinically cure 86% of patients with diabetic foot infections -- including some infections that were caused by methicillin-resistant Staphylococcus aureus (MRSA).

These data were presented at the 45th annual meeting of the Infectious Disease Society of America (IDSA) in San Diego, California. Ceftobiprole is licensed from, and is being co-developed with, Basilea Pharmaceutica Ltd.

Staphylococcus aureus is the predominant Gram-positive+ bacteria associated with many infections, including complicated skin and skin structure infections (cSSSI) and is carried by approximately 25-30% of the U.S. population. During the last 30 years, MRSA has become more prevalent as a cause of complicated skin and skin structure infections, including diabetic foot infections, which are particularly challenging to treat. In 1974, MRSA accounted for 2% of all Staphylococcus infections in the U.S. In 2004, this figure had risen to 63%.

According to the American Diabetes Association (ADA), nearly 21 million Americans suffer from diabetes. Diabetic foot infections can develop in the skin, muscle, or bones of the foot as a result of nerve damage and poor circulation associated with diabetes. A recent ADA study approximates that as many as 9% of Americans with diabetes will develop a diabetic foot infection, and that those who do develop such an infection are 55.7 times more likely to require hospitalization and 154.5 times more at risk of amputation.

Ceftobiprole belongs to a class of antibacterial agents known as cephalosporins, which are used to treat serious infections caused by Gram- negative++ and Gram-positive+ bacteria. In clinically evaluable patients, 500mg of ceftobiprole administered intravenously every eight hours (500mg IV q8h) demonst
'/>"/>

SOURCE Johnson & Johnson Pharmaceutical Research & Development,L.L.C.
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. New Study Shows That Extending Prophylaxis With Clexane / Lovenox (enoxaparin Sodium Injection) to 5 Weeks is More Effective Than 10 Days for Reducing the Risk of Venous Thromboembolism (VTE) in Acutely ill Medical Patients With Reduced Mobility
2. Eurands Zentase Effective in Treating Exocrine Pancreatic Insufficiency, Studies Show
3. Cimzia Effective in Reducing Signs and Symptoms of Rheumatoid Arthritis
4. Gabapentin Shown Effective for Fibromyalgia Pain
5. ApoCells Cancer Predictive Index Helps Oncologists Select the Most Effective Targeted Drug Therapy
6. Roxro Pharma’s Novel Intranasal Pain Reliever Effective, Well Tolerated in Phase 3 Study
7. XYOTAX More Cost Effective With Fewer Side Effects Than Gemcitabine or Vinorelbine in Treating Non-Small Cell Lung Cancer
8. Soliris Effective in PNH Patients With History of Aplastic Anemia and Myelodysplastic Syndromes
9. Repeated Radioimmunotherapy With 131I-Labetuzumab Appears Safe and Effective in Colorectal Cancer with Liver Metastases
10. Biotheras Imprime PGG Enhanced Effectiveness of Avastin in Cancer Study
11. Targanta Study Shows Oritavancin Treatment Effective in a Mouse Model of Anthrax
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/19/2014)... Sept. 19, 2014 "Copay coupons," ... sales of brand drugs among patients with prescription drug ... to a new report  from the Department ... Inspector General (OIG). Federal anti-kickback laws prohibit suppliers ... are subsidized by the federal government. ...
(Date:9/19/2014)... DUBLIN , September 19, 2014 /PRNewswire/ ... http://www.researchandmarkets.com/research/s6g5wm/global ) has announced the addition of ... report to their offering. ... devices have been broadly classified into wide ... are used for the treatment of different ...
(Date:9/19/2014)... 19, 2014  4WEB Medical announces the formal launch ... ankle osteotomy implants on the market today at ... meeting in Chicago .  The Osteotomy ... osteotomy needs with 74 size options included in one ... of only 15 to 18 implant sizes, which limited ...
Breaking Medicine Technology:PCMA: New OIG Report Cites Drug Manufacturer "Copay Coupon" Use in Medicare Part D 2Global Gynecological Devices Market 2014-2018: Key Vendors are Bayer, Boston Scientific, CooperSurgical, Ethicon, Hologic, Medtronic, Olympus and Stryker 2Global Gynecological Devices Market 2014-2018: Key Vendors are Bayer, Boston Scientific, CooperSurgical, Ethicon, Hologic, Medtronic, Olympus and Stryker 34WEB Medical Unveils 3D-Printed Osteotomy Truss System 2
... WOONSOCKET, R.I. , July 30 MultiCell Technologies, Inc. ... fresh new look and updated information about discovery technology platforms and ... common questions. , , ... "The new website is designed to inform our shareholders, scientists and ...
... July 29 As of late, the most prominently ... Lap-Band procedure, a minimally invasive operation in which an adjustable ... in order to restrict food capacity and promote weight loss. ... Lap Band surgery without the use of the band ...
Cached Medicine Technology:MultiCell Technologies Launches New Web Site 2MultiCell Technologies Launches New Web Site 3Sleeve Gastrectomy Procedure With Dr. Michael Feiz Serves as a Highly Effective Alternative to Lap Band Surgery 2Sleeve Gastrectomy Procedure With Dr. Michael Feiz Serves as a Highly Effective Alternative to Lap Band Surgery 3
(Date:9/21/2014)... new study of cancer patients who smoke, those using ... dependent and equally or less likely to have quit ... Cancer , a peer-reviewed journal of the American ... benefits of e-cigarettes for helping cancer patients give up ... all cancer patients who smoke should be advised to ...
(Date:9/21/2014)... UNIWIGS, one of the leading online stores of ... offers a line of human hair lace wigs inspired by ... shows people what the latest celebrity hairstyles are. ... are 4 different hairstyles to choose from: a style of ... wigs and a hot ombre red lace wig. People can ...
(Date:9/21/2014)... September 21, 2014 Hastings and Hastings, ... announces record demand for aggressively discounted accident victim attorney’s ... throughout the Valley each year, it is more important ... to discounted attorney’s fees as a way to enjoy ... Hastings has been a frontrunner when it comes to ...
(Date:9/21/2014)... 2014 More than a quarter of house ... start in one of two ways. The first type of ... The second type of dryer fire occurs when lint builds ... also catch fire due to malfunctioning electrical systems so if it ... a look!) Here are some ways that you can prevent ...
(Date:9/21/2014)... trigger an allergy to peanuts than raw peanuts, suggests ... say that specific chemical changes caused by the high ... the body,s immune system, ,priming, the body to set ... sees any peanuts. , The results might explain the ... in the Western world compared to populations in East ...
Breaking Medicine News(10 mins):Health News:E-cigarettes unhelpful in smoking cessation among cancer patients 2Health News:UniWigs New Arrivals Just In- Human Hair Lace Wigs Inspired By Famous Celebrities 2Health News:Hastings & Hastings Announces Record Demand For Aggressively Discounted Accident Victim Attorney’s Fees 2Health News:Hastings & Hastings Announces Record Demand For Aggressively Discounted Accident Victim Attorney’s Fees 3Health News:Restoration Local Offers Tips to Avoid Dryer Fires 2Health News:Restoration Local Offers Tips to Avoid Dryer Fires 3Health News:Dry roasting could help trigger peanut allergy 2
... Scottish ministers have announced a ?4 million cash boost to fight ... cash is expected to go towards stemming Scotland's high rates of ... sufferers. ,It has been estimated that about 20,000 people ... to be a "silent killer" among Scotland's drug users - in ...
... from the University of Newcastle, UK, a drug used ... the damage caused in cirrhosis of the liver.// ... scarring linked with cirrhosis is irreversible, the recent study ... by using Sulphasalazine.,Heavy drinking and obesity has resulted in ...
... reliable tests to detect early stages of cancerous growth in ... colon cancers successfully//, is often a procedure associated with a ... by going through this procedure to rule out or confirm ... fear of the discomfort they may have to go through. ...
... the young, so all anti-binge drinking sermons are by default ... fence//, it has come to light that the fifty and ... of drinks, to the extent of causing irreparable damage to ... can cause damage to the liver and brain. ...
... A new study says that uterine cancer is more lethal ... found that black women// with uterine cancer survived for 10.2 ... the same treatment. ,Dr. G. Larry Maxwell and his ... said black women were 26 percent more likely to die ...
... those who feel low during these nine months should seek ... Tommy's Baby Charity here surveyed 1,000 women about how they ... ,The survey found that three in five women ... Two thirds felt even more exhausted than they expected and ...
Cached Medicine News:Health News:Scotland’s Fight against Hepatitis C Boosted by ? 2
The Doro Halo retractor system is designed for all neurosurgical applications where retraction of the brain tissue and an armrest is required....
Molt 9, excellent for subperiosteal tunneling....
Love-Adson periosteal elevator, semi sharp, blade width 3/16" (5 mm), length 6 1/2" (165 mm)....
Iowa University periosteal elevator, blade width 11/16" (17 mm), length 7 1/4" (184 mm)....
Medicine Products: