Navigation Links
New Data Show CIMZIA(R) (certolizumab pegol) Provides Sustained and Significant Symptom Improvement in Moderate to Severe Crohn's Patients
Date:10/26/2009

ption for those living with this devastating and debilitating disease. The long-term efficacy data solidify CIMZIA's potential to help many patients throughout the course of their disease," said David Robinson, vice president and general manager of UCB's Immunology Business Unit.

Earlier this year, UCB announced that CIMZIA is available to moderate to severe Crohn's patients in a pre-filled syringe, developed in partnership with OXO Good Grips®( )for subcutaneous self-administration once every four weeks after initial dosing. CIMZIA, manufactured by UCB, was approved by the U.S. Food and Drug Administration on April 22, 2008 for reducing signs and symptoms of moderate to severe Crohn's disease and maintaining clinical response in adult patients who have had an inadequate response to conventional therapy.

About the PRECiSE Clinical Trial Program

PRECiSE (PEGylated Antibody Fragment Evaluation in Crohn's Disease: Safety and Efficacy), one of the largest, most comprehensive development programs for an anti-TNF for Crohn's disease, is composed of two placebo-controlled studies and two open-label safety follow-up studies. In 2007, the two former studies were published in the New England Journal of Medicine (NEJM). The studies demonstrated that patients with moderate to severe Crohn's disease achieved and sustained clinical response with CIMZIA for up to six months, compared to placebo. In the first follow-up study, patients completing both initial studies were to be given CIMZIA every four weeks for up to seven years. In the second follow-up study, patients who relapsed in either initial study (defined as an increase in CDAI of >70 or absolute CDAI of >350) were re-introduced to CIMZIA every four weeks to be continued for up to seven years, with a single additional dose at week 2. The most common adverse events reported were headache, nasopharyngitis, cough and abdominal pain. The incidence of seriou
'/>"/>

SOURCE UCB
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8 9 10

Related medicine technology :

1. CIMZIA(R) (Certolizumab Pegol) Provides Rapid and Sustained Relief from Signs and Symptoms of Rheumatoid Arthritis for Two Years
2. CIMZIA(R) (Certolizumab Pegol) Provides Long-Term Benefit Without Dose Escalation in Crohns Disease Patients
3. CIMZIA(R) (certolizumab pegol) Reduces Intestinal Lesions and Induces Endoscopic Improvement in Crohns Patients
4. Cimzia(R) Provides Long-Term Efficacy with Stable Dosing in Crohns Disease
5. CIMZIA(R) (certolizumab pegol), Significantly Reduces Structural Damage and Rheumatoid Arthritis Signs & Symptoms for Up to One Year
6. e-Zassi.com Provides Industry With Online U.S. FDA Regulatory Calculator for Rapid Medical Device Technology Assessment
7. Access Pharmaceuticals Provides Update on MuGard Commercial Launch and First European Clinicians Feedback
8. New ALS Patient Simulator Advanced Provides Valuable Training for EMS Teams and In-Hospital Emergency Personnel
9. CardioGenics Holdings Inc. Provides Update on FINRA Submission Regarding Name Change
10. Young Innovations, Inc. Provides Third Quarter Conference Call Details
11. Helix BioPharma Provides Updates on Topical Interferon Alpha-2b and L-DOS47 Following Pre-IND Meetings With the U.S. FDA
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/28/2015)... July 28, 2015 Amgen (NASDAQ: AMGN ... a $0.79 per share dividend for the third quarter ... 8, 2015, to all stockholders of record as of ... About Amgen Amgen is committed to unlocking ... illnesses by discovering, developing, manufacturing and delivering innovative human ...
(Date:7/28/2015)... July 28, 2015   Heska Corporation  (NASDAQ: ... provider of  advanced veterinary diagnostic and other specialty ... the new Element i ® Immunodiagnostic Analyzer. ... for key health concerns, including thyroid disorders, Cushing,s ... a compact bench top analyzer that delivers rapid ...
(Date:7/28/2015)... LOUIS, July 28, 2015  Express Scripts Holding Company ... income attributable to Express Scripts stockholders of $600.1 million, ... share, as detailed in Table 4, were $1.44 for ... is clear many companies across healthcare are validating the ... and Chief Executive Officer. "But, what matters most is ...
Breaking Medicine Technology:Amgen Announces 2015 Third Quarter Dividend 2Amgen Announces 2015 Third Quarter Dividend 3Heska Announces Veterinary Market's first and only point of care Analyzer for TSH, Total T4, and Cortisol results in minutes 2Heska Announces Veterinary Market's first and only point of care Analyzer for TSH, Total T4, and Cortisol results in minutes 3Express Scripts Announces 2nd Quarter Results; Increases 2015 Guidance Range 2Express Scripts Announces 2nd Quarter Results; Increases 2015 Guidance Range 3Express Scripts Announces 2nd Quarter Results; Increases 2015 Guidance Range 4Express Scripts Announces 2nd Quarter Results; Increases 2015 Guidance Range 5Express Scripts Announces 2nd Quarter Results; Increases 2015 Guidance Range 6Express Scripts Announces 2nd Quarter Results; Increases 2015 Guidance Range 7Express Scripts Announces 2nd Quarter Results; Increases 2015 Guidance Range 8Express Scripts Announces 2nd Quarter Results; Increases 2015 Guidance Range 9Express Scripts Announces 2nd Quarter Results; Increases 2015 Guidance Range 10Express Scripts Announces 2nd Quarter Results; Increases 2015 Guidance Range 11Express Scripts Announces 2nd Quarter Results; Increases 2015 Guidance Range 12Express Scripts Announces 2nd Quarter Results; Increases 2015 Guidance Range 13Express Scripts Announces 2nd Quarter Results; Increases 2015 Guidance Range 14Express Scripts Announces 2nd Quarter Results; Increases 2015 Guidance Range 15Express Scripts Announces 2nd Quarter Results; Increases 2015 Guidance Range 16Express Scripts Announces 2nd Quarter Results; Increases 2015 Guidance Range 17Express Scripts Announces 2nd Quarter Results; Increases 2015 Guidance Range 18Express Scripts Announces 2nd Quarter Results; Increases 2015 Guidance Range 19Express Scripts Announces 2nd Quarter Results; Increases 2015 Guidance Range 20Express Scripts Announces 2nd Quarter Results; Increases 2015 Guidance Range 21Express Scripts Announces 2nd Quarter Results; Increases 2015 Guidance Range 22Express Scripts Announces 2nd Quarter Results; Increases 2015 Guidance Range 23Express Scripts Announces 2nd Quarter Results; Increases 2015 Guidance Range 24Express Scripts Announces 2nd Quarter Results; Increases 2015 Guidance Range 25
... FRANCISCO, Calif., Feb. 3 Rigel,Pharmaceuticals, Inc. (Nasdaq: ... will delay,further partnership discussions regarding R788 until after ... are available. The company expects that,these ... the understanding of R788,s potential and may therefore,drive ...
... Feb. 2 Adolescents and young adults who ... than non-users to have disrupted brain development, according ... in areas of the brain that interconnect brain ... executive functioning skills. The findings are of particular ...
Cached Medicine Technology:Rigel Expects R788 Partnership After Phase 2b Clinical Trials Results 2Rigel Expects R788 Partnership After Phase 2b Clinical Trials Results 3Rigel Expects R788 Partnership After Phase 2b Clinical Trials Results 4Rigel Expects R788 Partnership After Phase 2b Clinical Trials Results 5Heavy Marijuana Use May Damage Developing Brain in Teens, Young Adults 2Heavy Marijuana Use May Damage Developing Brain in Teens, Young Adults 3
(Date:7/28/2015)... ... ... Her, a unique women’s wellness and lifestyle event designed to inspire and empower women ... level, announced today an influential line-up of inspiring speakers, including Mallika Chopra, founder of ... County based non-profit that works locally and globally to help girls become leaders in ...
(Date:7/28/2015)... Port Richey, FL (PRWEB) , ... July 28, ... ... Brown University and The Miriam Hospital examines outcomes for inmates who continued methadone ... found the latter group was more likely to relapse to opiate use (1) ...
(Date:7/28/2015)... Tenn. (PRWEB) , ... July 28, 2015 , ... ... July through October this year, as volunteers celebrate the 14th year of raising ... and Tracy Lawrence in downtown Savannah for this year’s main concert Saturday, Oct. ...
(Date:7/28/2015)... ... July 28, 2015 , ... By 2016, the number of smartphones worldwide ... with customers on a highly personal basis, increasing customer loyalty. However, capitalizing on this ... opportunities or lose customers to more nimble competitors. , The Open Mobile Summit 2015 ...
(Date:7/28/2015)... ... ... Dr. Edward Buckingham and Buckingham Center for Facial Plastic Surgery, is ... to Austin from Philadelphia, Dr. Roy will be completing his Fellowship in facial plastic ... by the American Academy of Facial Plastic and Reconstructive Surgery. , Since 1969, ...
Breaking Medicine News(10 mins):Health News:Women’s Healthy Living Event Mindful Her Set for October 24, 2015 in Orange County 2Health News:Women’s Healthy Living Event Mindful Her Set for October 24, 2015 in Orange County 3Health News:Novus Medical Detox Center Analyzes Methadone Study Findings and Implications for Opiate Abuse Treatment 2Health News:Novus Medical Detox Center Analyzes Methadone Study Findings and Implications for Opiate Abuse Treatment 3Health News:Novus Medical Detox Center Analyzes Methadone Study Findings and Implications for Opiate Abuse Treatment 4Health News:Worley’s 14th Tennessee River Run Will Host Wade Hayes, Lorrie Morgan, Tracy Lawrence and Others 2Health News:Worley’s 14th Tennessee River Run Will Host Wade Hayes, Lorrie Morgan, Tracy Lawrence and Others 3Health News:Open Mobile Media: Etsy, Google, The Weather Company, CBS, TaskRabbit and New York Times: Moving from Web to Mobile-First 2Health News:Open Mobile Media: Etsy, Google, The Weather Company, CBS, TaskRabbit and New York Times: Moving from Web to Mobile-First 3Health News:Buckingham Center for Facial Plastic Surgery Welcomes Fellow 2Health News:Buckingham Center for Facial Plastic Surgery Welcomes Fellow 3
... been found that a herbal supplement can effectively combat cocaine ... a potential agent to modulate the effects of cocaine addiction.// ... treatment of heroin addiction, and possibly alcoholism. ,NAC ... for its antioxidant effects. Antioxidants are agents that clean up ...
... Huang and his team from Gladstone Institute of Neurological ... is responsible for causing Alzheimer's disease //that acts by ... cells due to the protein fragments released from apoE. ... responsible for causing Alzheimer’s disease by not providing the ...
... Ontario’s hospitals are getting longer, according to Government data which ... the Conservative health critic.// The waiting time rose from 34 ... cancer surgery, while it rose from 139 days to 142 ... days for cardiac surgeries, while in the case of angioplasty, ...
... levels of lead in soil and sediments left behind ... heightened health threat to returning residents, especially children, says ... from the area, lead levels were as much as ... considers safe, according to researchers at Texas Tech University. ...
... Failure of Democratic Nation Building: Ideology Meets Evolution' Dr. Steven ... or cannot be forcibly thrusted on a nation. ... hierarchical and authoritarian social and political // structures. ... before it is accepted by the people. ,It ...
... the Rockefeller University revealed that good taste is not an ... conducted on C.elagans which is a very simple nematode. It ... harmless and pathogenic ones).It has 302 neurons totally which can ... for the nervous system to function are very similar to ...
Cached Medicine News:Health News:A herbal drug addiction releiver 2Health News:Lead levels in disturbed soil post-Katrina unsafe 2Health News:Lead levels in disturbed soil post-Katrina unsafe 3Health News:Worms Learn To Choose Their Diet 2
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
Medicine Products: