Navigation Links
New Data Offers Insights Into the Potential Role for TYKERB(R) (Lapatinib) in Non-Cytotoxic Chemotherapy-Based Treatment Regimens
Date:6/1/2008

TYKERB Demonstrates Activity in Combination with Other Targeted Therapies

and as Monotherapy Across A Range of Breast Cancer Settings - First Phase II data investigating the dual inhibition of HER2 and VEGF pathways with two oral, small molecule tyrosine-kinase inhibitors (TYKERB and pazopanib) demonstrates activity in first-line HER2 (ErbB2) positive

breast cancer(1)

- Phase II results combining TYKERB and AVASTIN(R) (bevacizumab), a monoclonal antibody, shows activity in recurrent metastatic HER2-positive

breast cancer(2)

- Final results from the largest prospective trial evaluating TYKERB monotherapy as a treatment for relapsed inflammatory breast cancer (IBC) demonstrates activity in this highly aggressive and difficult to treat

disease(3)

LONDON, and PHILADELPHIA, June 1 /PRNewswire-FirstCall/ -- GlaxoSmithKline today announced the results of three studies evaluating TYKERB -- an oral, small molecule inhibitor of HER2 -- in various breast cancer settings, either in combination with other targeted therapies or as a monotherapy. Use of TYKERB in these settings is investigational. Results from these studies are being presented during the annual American Society of Clinical Oncology (ASCO) meeting in Chicago, May 30 - June 3, 2008.

Multiple cellular pathways influence the growth and metastatic potential of tumors, which is thought to be related to the ability of cancer cells to develop primary or acquired resistance.(4) It is believed that targeted inhibition of several tumor cell signaling pathways may be more effective than inhibition of a single pathway alone.(4)

"Targeted therapies, either used in combination or as a single agent, are the future of cancer treatment and may have the potential to treat patients more effectively," said Dr. Paolo Paoletti, Senior Vice President of the Oncology Medicine Developm
'/>"/>

SOURCE GlaxoSmithKline
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8 9 10

Related medicine technology :

1. RediClinic Offers Affordable New Plan Clinically Shown to Double a Persons Chance to Stop Smoking
2. Spine Institute of Louisiana Offers Cervical Spine Motion Preservation as an Alternative to Fusion Surgery
3. CVS/pharmacy Offers Flu Vaccinations in Over 4,000 Stores
4. Spit for the Cure Offers Unique Opportunity for Women to Participate in Breast Cancer Research
5. Concentra Offers Flu Vaccines to Keep America Working
6. New Report by Pediatricians Finds Gaps in Preparing to Protect Kids From Pandemic Flu, Offers Recommendations
7. UPDATE: New Report by Pediatricians Finds Gaps in Preparing to Protect Kids From Pandemic Flu, Offers Recommendations
8. New UNAIDS Report Offers Encouraging News, But Most HIV-Positive Mothers Still Not Getting the Care & Treatment They Need
9. New Data Published in The Lancet Show GSKs ROTARIX(R) Offers Protection Against the Most Common Circulating Rotavirus Types
10. Researcher Investigates Disparities in Doctor-Patient Information Exchange During Clinical Trial Offers
11. New Report Offers Hope for Closing Health Gap for African Americans, With Nearly 700 Medicines in Pipeline
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/26/2015)... 26, 2015 According to ... Safety Software Market by Functionality (Adverse Event Reporting, Fully ... End-user (Pharma & Biotech Companies, CROs, BPOs) - ... Pharmacovigilance and Drug Safety Software Market is poised ... 2014-2019, and is expected to reach a value ...
(Date:3/26/2015)... FRANKLIN LAKES, N.J. , March 26, 2015 /PRNewswire/ ... announced today that it will commence offers to exchange ... series issued by CareFusion Corporation, a wholly owned subsidiary ... as described in the table below. A Registration Statement ... issuance of the New Notes was filed with the ...
(Date:3/26/2015)... PROSPECT, Illinois , 26. März 2015 ... Pharmacy® (NABP®) wird vom 1. April 2015 an ... von allen abgebenden Apotheken annehmen. Seit dem ... hat der Verband über 275 .pharmacy-Domainnamen zugelassen, ... während dieser Zeiten beantragt wurden. Die NABP ...
Breaking Medicine Technology:Pharmacovigilance and Drug Safety Software Market Worth $154.1 Million by 2019 2Pharmacovigilance and Drug Safety Software Market Worth $154.1 Million by 2019 3Pharmacovigilance and Drug Safety Software Market Worth $154.1 Million by 2019 4Becton, Dickinson and Company to Commence Exchange Offers 2Becton, Dickinson and Company to Commence Exchange Offers 3Becton, Dickinson and Company to Commence Exchange Offers 4Becton, Dickinson and Company to Commence Exchange Offers 5Alle abgebenden Apotheken berechtigt, um ab dem 1. April 2015 .Pharmacy-Domainnamen zu beantragen 2
... 2012 /PRNewswire-Asia/ -- Sinovac Biotech Ltd. (Nasdaq: SVA ... that it will release its unaudited financial results for the ... May 15, 2012.  The Company will host a conference call ... 15, 2012 at 8:00 p.m. China Standard Time) to review ...
... May 8, 2012 Perrigo Company (Nasdaq: ... quarter ended March 31, 2012. (Logo:   ... Joseph C. Papa commented, "We are very pleased with ... These strong results were made possible by the continued ...
Cached Medicine Technology:Sinovac to Host Conference Call to Report First Quarter 2012 Unaudited Financial Results 2Perrigo Reports Record Third Quarter Revenue And Earnings And Raises Full Year EPS Guidance 2Perrigo Reports Record Third Quarter Revenue And Earnings And Raises Full Year EPS Guidance 3Perrigo Reports Record Third Quarter Revenue And Earnings And Raises Full Year EPS Guidance 4Perrigo Reports Record Third Quarter Revenue And Earnings And Raises Full Year EPS Guidance 5Perrigo Reports Record Third Quarter Revenue And Earnings And Raises Full Year EPS Guidance 6Perrigo Reports Record Third Quarter Revenue And Earnings And Raises Full Year EPS Guidance 7Perrigo Reports Record Third Quarter Revenue And Earnings And Raises Full Year EPS Guidance 8Perrigo Reports Record Third Quarter Revenue And Earnings And Raises Full Year EPS Guidance 9Perrigo Reports Record Third Quarter Revenue And Earnings And Raises Full Year EPS Guidance 10Perrigo Reports Record Third Quarter Revenue And Earnings And Raises Full Year EPS Guidance 11Perrigo Reports Record Third Quarter Revenue And Earnings And Raises Full Year EPS Guidance 12Perrigo Reports Record Third Quarter Revenue And Earnings And Raises Full Year EPS Guidance 13Perrigo Reports Record Third Quarter Revenue And Earnings And Raises Full Year EPS Guidance 14Perrigo Reports Record Third Quarter Revenue And Earnings And Raises Full Year EPS Guidance 15Perrigo Reports Record Third Quarter Revenue And Earnings And Raises Full Year EPS Guidance 16Perrigo Reports Record Third Quarter Revenue And Earnings And Raises Full Year EPS Guidance 17Perrigo Reports Record Third Quarter Revenue And Earnings And Raises Full Year EPS Guidance 18
(Date:3/26/2015)... Visiting Nurse Association of Northern New Jersey ... the Way, Brightening the Day, on Friday, May 1, ... Morristown, NJ. , Guests will enjoy an elegant ... delightful cuisine, an extensive silent auction and heart-warming testimony ... awards will be presented to this year’s honorees. ...
(Date:3/26/2015)... San Frencisco, CA (PRWEB) March 26, 2015 ... Implant Center are proud to announce expanded offerings for ... The San Francisco Dental Implant Center has long been ... efforts have expanded its offerings to meet the strong ... pride in our reputation as a top-rated dental implant ...
(Date:3/26/2015)... 2015 Innovative research and additional ... preventing often fatal ruptures, says The Bee Foundation, ... awareness of brain aneurysms and funding innovative research ... national attention with the death of longtime ... last Friday after suffering a ruptured brain aneurysm. ...
(Date:3/26/2015)... March 26, 2015 The National ... Assessment and Evaluation , has announced its partnership ... institutions, organizations, and corporations to accurately and securely ... learning. , Utilizing Questionmark’s state-of-the-art software and ... will offer improved delivery of the seventy-five to ...
(Date:3/26/2015)... Volunteers will collectively walk hundreds of miles ... funds to support the American Parkinson Disease Association’s ... the Cure. The Optimism Walk campaign is ... than 20 locations including, Boston, Chicago, Connecticut, Madison, Nashville, ... Seattle, St. Louis, New York, Nevada, South Florida, Vermont, ...
Breaking Medicine News(10 mins):Health News:Morristown VNA Fundraiser to Honor Distinguished Community Members 2Health News:Bay Area Dental Implant Specialist, Dr. Alex Rabinovich Announces Regional Educational Strategy 2Health News:Bay Area Dental Implant Specialist, Dr. Alex Rabinovich Announces Regional Educational Strategy 3Health News:Research and Funding Are Keys to Raising Awareness and Ultimately Preventing Fatal Brain Aneurysm Ruptures 2Health News:Research and Funding Are Keys to Raising Awareness and Ultimately Preventing Fatal Brain Aneurysm Ruptures 3Health News:NLN Testing Services Announces Improved Delivery and Analytics Software and Newly Developed and Revised Exams 2Health News:American Parkinson Disease Association 2015 Optimism Walk Season Launches Nationwide 2
... ... ... Wellness Center is now offering Kennedy Spinal Decompression Therapy to Springfield area residents suffering ... for lower back and neck pain sufferers., , ,Spinal Decompression Therapy has been clinically ...
... ... payroll processing time thus freeing staff to spend more time serving patients and less time ... ... improvement in staff productivity and payroll processing time thus freeing staff to spend more time ...
... ) today announced that it has entered into an agreement with Pfizer under which Sigma-Aldrich will sell approximately 100 Pfizer-developed small molecule compounds to ... ... , , ... ...
... The Autism Consortium, an innovative research, clinical and family ... for families with autism spectrum disorders (ASDs), announced today ... testing methods for autism spectrum disorders is available from ... in their eFirst pages today and will appear in ...
... kind to date using cardiac computed tomography angiography, people ... artery disease are at higher risk of developing obstructive ... Ford Hospital researchers say. Researchers analyzed the data ... tomography angiography and found that those with a family ...
... ACL, meniscus at same time is one advance, ,Tommy John, ... Repairing a torn knee meniscus at the same time as ... children, a new study finds. , Meniscus cartilage acts as ... one of four major ligaments in the knee. , This ...
Cached Medicine News:Health News:Chiropractor Springfield, VA - Dr. Todd P. Sullivan Announces The Addition of Spinal Decompression Therapy 2Health News:Hospice of Baton Rouge Selects CellTrak as a Good Steward of Time and Talent 2Health News:Hospice of Baton Rouge Selects CellTrak as a Good Steward of Time and Talent 3Health News:Hospice of Baton Rouge Selects CellTrak as a Good Steward of Time and Talent 4Health News:Sigma-Aldrich Reaches Agreement to Sell Pfizer's Bioactive Small Molecule Compounds 2Health News:Sigma-Aldrich Reaches Agreement to Sell Pfizer's Bioactive Small Molecule Compounds 3Health News:Sigma-Aldrich Reaches Agreement to Sell Pfizer's Bioactive Small Molecule Compounds 4Health News:Sigma-Aldrich Reaches Agreement to Sell Pfizer's Bioactive Small Molecule Compounds 5Health News:Autism Consortium study in Pediatrics shows CMA finds more genetic abnormalities than current tests 2Health News:Autism Consortium study in Pediatrics shows CMA finds more genetic abnormalities than current tests 3Health News:Autism Consortium study in Pediatrics shows CMA finds more genetic abnormalities than current tests 4Health News:Family history is strong predictor of obstructive coronary artery disease using CCTA 2Health News:Strides Seen in Orthopedic Surgery for Kids 2
... 1 (IGF-1) is a polypeptide of 70 amino ... number of related insulin-like growth factors present in ... homology with proinsulin and has a number of ... growth hormone (GH) dependent to a high degree, ...
...
...
...
Medicine Products: