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New Data Highlighting Possible Impact of ESA Reimbursement Policies on Patient Care, Nation's Blood Supply, to be Presented at American Society of Clinical Oncology (ASCO) Annual Meeting
Date:5/16/2008

r Patients Receiving Chemotherapy

James Gilmore, PharmD, Georgia Cancer Associates, Atlanta, GA

Presentation: Health Svcs Research, Sunday, June 1, 2008, 8:00am - 12:00pm CST, S Hall A1

Abstract Number: 6548

The purpose of this study was to describe the association between the CMS NCD and clinical outcomes for patients with chemotherapy-induced anemia requiring ESA therapy, as determined by the treating physician. A total of 285 Medicare patients receiving two or more ESA doses with concurrent chemotherapy and a cancer diagnosis were included in this retrospective observational study of an electronic medical record database.

Transfusion Outcomes Among Oncology Patients Initiated with Erythropoiesis-Stimulating Agents (ESAs) at Baseline (BL) Hemoglobin (Hb) of < 10 v. 10-11g/dL: Observational Data from the Dosing and Outcomes Study of Erythropoiesis-Stimulating Therapies (DOSE) Registry

Tanya Burton, Ph.D., Abt Associates, Lexington, MA

Publication Number: 20637

Limited real-world data exist on transfusion patterns in patients initiated with ESAs at different baseline Hb levels. Observational data from an ongoing, prospective registry of 1,059 ESA-treated patients in 59 U.S. oncology clinics from December 2003 to November 2007 were analyzed to investigate transfusion outcomes in chemotherapy-treated oncology patients initiated on ESAs at baseline Hb of <10 g/dL vs. 10-11 g/dL. Hospital- and community-based outpatient practices were included in the analysis.

About PROCRIT (Epoetin alfa)

PROCRIT(R) (Epoetin alfa) is an ESA used for the treatment of anemia in patients with most types of cancer receiving chemotherapy, with chronic renal failure who are on dialysis and those who are not on dialysis, who are being treated with zidovudine for HIV infection, and to reduce the need for transfusion in anemic patients who are scheduled for elective noncardiac, nonvascular surgery. Depending on the country in
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SOURCE Ortho Biotech Products, L.P.
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