Navigation Links
New Data Highlight Positive Results of Namenda(R) (memantine HCl) Once-Daily Extended-Release Formulation
Date:7/30/2008

activities using the 19-item AD Cooperative Study-Activities of Daily Living scale (ADCS-ADL) demonstrated maintenance of function during the study period, but this was not significantly different from placebo (p=0.18).

The study also demonstrated that once-daily extended-release memantine was well tolerated. The treatment-emergent AEs (TEAEs) profile was similar between the groups; no TEAEs were experienced by greater than or equal to 5% of memantine patients, and at an incidence at least twice that of the placebo group. The most common adverse events occurring at a higher rate than placebo were dizziness (4.7% vs 1.5%), diarrhea (5.0% vs 3.9%), and headache (5.6% vs 5.1%).

About Alzheimer's Disease

Alzheimer's disease is a progressive, degenerative disease of the brain and the most common type of dementia. Dementia is used to describe the progressive loss of cognitive, intellectual, or functional abilities. By 2050, the number of individuals age 65 and over with Alzheimer's disease could range from 11 million to 16 million. Currently, all Alzheimer's disease medications approved in the US other than Namenda belong to a class of agents called cholinesterase inhibitors.

About Namenda

Namenda (memantine HCl) is the first in a class of medications with a unique mechanism of action that focuses on the glutamate pathway, a target for the treatment of Alzheimer's disease. Indicated for the treatment of moderate to severe Alzheimer's disease, the FDA approved Namenda in October 2003 based on three studies of Namenda used alone or in combination with another Alzheimer's disease drug. At present, the recommended dose of Namenda is 10 mg two times a day (20 mg/day).

Namenda is contraindicated in patients with known hypersensitivity to memantine HCl or any excipients used in the formulation. The most common adverse events reported with Namenda vs placebo (greater than or equal to 5% and higher than placebo) were dizziness, confusion,
'/>"/>

SOURCE Forest Laboratories, Inc.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Focal Cryoablation Highlighted in Urology Times Best of AUA Orlando 2008
2. Journal of Clinical Oncology Article Highlights CellSearch(TM) Circulating Tumor Cell Test in Treatment of Metastatic Colorectal Cancer
3. Medarex Highlights Strength in Antibody Development and Underlying Pipeline Strategy at R&D Day Event in New York City
4. Marketing of Diagnostics and deCODEme(TM), Recent Progress in Drug Development to be Highlighted at deCODE R&D Event
5. June 2008 Mayo Clinic Womens HealthSource Highlights Shingles Vaccine for Pain Prevention, Tips to Avoid Antibiotic Resistant Infections, and Benefits of Broad Genetic Testing
6. New Subset Analysis of AndroGel(R) Data Highlights Efficacy - Regardless of BMI
7. Isis Highlights Robust Drug Portfolio for Diabetes and Obesity at ADA Conference
8. Preliminary Analyses from Phase 2 Genzyme Study Highlight Efficacy and Safety of Clofarabine in Older Adult AML Patients
9. Keryx Biopharmaceuticals, Inc. Announces Poster Presentation Highlighting Observed Clinical Activity of KRX-0401 (Perifosine) at the American Society of Clinical Oncology Meeting in Chicago, Illinois
10. ATHENA Clinical Results with Dronedarone (Multaq(R)) Highlighted at the World Cardiology Congress
11. Seven Presentations by Two Independent Research Groups Highlight Advantages of Pressure Cycling Technology (PCT) at Scientific Symposia in Philadelphia, Boston, and New York City
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/21/2014)... Aug. 21, 2014 Professional Compounding Centers ... medicine by awarding the three best scientific presentations ... (EuPFI) conference . The Formulating Better Medicines ... in Athens, Greece , includes ... and professionals, from which three winners will be ...
(Date:8/21/2014)... MENLO PARK, Calif. , Aug. 21, 2014 /PRNewswire/ ... company in the emerging field of regenerative medicine, announced ... ("Nat") Ricciardi to the Company,s newly expanded Board of ... now comprises eight directors, three of whom are independent. ... years of experience working with emerging growth companies. He ...
(Date:8/20/2014)... Aug. 20, 2014 The National Association ... latest results achieved by the real-time, pseudoephedrine (PSE) ... National Precursor Log Exchange (NPLEx), automatically blocks unlawful ... down meth offenders and make arrests. Data released ... Kansas blocked the sale of more ...
Breaking Medicine Technology:Professional Compounding Centers of America will award top poster-session winners at European Paediatric Formulation Initiative in Athens 2Asterias Biotherapeutics Appoints Two Independent Directors and Announces Completion of Series A Common Stock Distribution 2Asterias Biotherapeutics Appoints Two Independent Directors and Announces Completion of Series A Common Stock Distribution 3Asterias Biotherapeutics Appoints Two Independent Directors and Announces Completion of Series A Common Stock Distribution 4Kansas's Stop-Sale System Achieves Significant Results In Battle Against Meth 2
... 2011 Medizone International, Inc. (MZEI:OB MZEI:QB) reports ... Patent No 2735739 for processes and systems relating ... AsepticSure™ hospital disinfection product. Medizone,s ... significance of this Grant: "This foundational lead patent ...
... Leading event organiser UBM has announced a record ... pharmaceutical events including CPhI Worldwide for pharmaceutical ingredients, ... for equipment, machinery and technology and the new ... Frankfurt, Germany from the 25th to 27th October ...
Cached Medicine Technology:Canadian Patent Issued to Medizone International for AsepticSure™ Disinfection Technology 2Record Year for UBM's Pharma Events in Frankfurt 2Record Year for UBM's Pharma Events in Frankfurt 3Record Year for UBM's Pharma Events in Frankfurt 4
(Date:8/21/2014)... The results of a large, retrospectives ... of the American Medical Association (JAMA) show that 3D ... unnecessary recalls. Memorial Healthcare System was one of 13 ... study confirms what we already know – 3D mammography ... to find and, at the same time, saves women ...
(Date:8/21/2014)... (PRWEB) August 21, 2014 According to ... “Home Audio Equipment (Product Types - Home Theatre in-a-box, ... Market - Global Industry Analysis, Size, Share, Growth, Trends ... at USD 15.94 billion in 2012 and is expected ... a CAGR of 3.7% from 2013 to 2019. Europe ...
(Date:8/21/2014)... Aug. 21, 2014 (HealthDay News) -- In a new ... pregnant women avoid eating tuna due to concerns about ... which is second only to shrimp as the most ... pregnant women to avoid all tuna," Jean Halloran, director ... division of Consumer Reports, said in a news release ...
(Date:8/21/2014)... (PRWEB) August 21, 2014 Pleio, ... adherence, is launching a new suite of services ... offerings assist retail pharmacy by applying proven behavior ... classes, resulting in increased medication adherence, higher PDC ... As such, Pleio’s PDC-targeted offerings align retail’s desire ...
(Date:8/21/2014)... scientific collaboration led by Baylor College of Medicine has ... a rare form of kidney cancer, providing new insights ... as well. , The collaboration, a project of the ... , completed the sequence of chromophobe renal cell carcinoma ... Cancer Cell . , "The Cancer Genome Atlas ...
Breaking Medicine News(10 mins):Health News:Dr. Mary Hayes: Study Shows 3D Mammography Finds More Invasive Cancers While Reducing Unnecessary Recalls 2Health News:Home Audio Equipment Market Expected to Reach USD 20.68 Billion in 2019 2Health News:Home Audio Equipment Market Expected to Reach USD 20.68 Billion in 2019 3Health News:Consumer Reports Advises Pregnant Women to Avoid Tuna 2Health News:Pleio, Inc. Expands Adherence Offerings For Retail Pharmacy 2Health News:Sequence of rare kidney cancer reveals unique alterations involving telomerase 2Health News:Sequence of rare kidney cancer reveals unique alterations involving telomerase 3
... researchers have for the first time miniaturised an important ... microfluidic chip . ,The new technology, developed ... the possibility of better, faster cancer treatment and greater ... test that detects mutations in chromosomes for a number ...
... A recent survey has found that parents are increasingly monitoring ... ,According to the Kaiser Family Foundation's national survey ... say that they "closely" keep an eye on their children's ... do more." ,"While parents are still concerned about ...
... device that mimics the naturally disinfecting quality of fresh ... radicals into the atmosphere , killing microbes within minutes. ... used to purge hospital wards of superbugs. ... all the windows of hospital wards, but that's not ...
... research, examining the upper echelons of the human brain's ... two corresponding commanders in charge of the brain . ... in St. Louis found that these two commanders are ... other but still work toward a common intention i.e. ...
... diet can increase the risks of bowel cancer. The research ... acid in the gut , due to the consumption of ... colorectal cancer, is produced by bacteria and helps in fighting ... found that the widely practised Atkins Diet -can lead ...
... was no point blaming China for rising carbon dioxide (CO2) ... have already become the world's biggest polluter. ,In ... of Britain's Foreign Office was quoted as saying: "It is ... every week". However, he went on to say that it ...
Cached Medicine News:Health News:Now, FISH on a Chip for Quicker, Cost-effective Cancer Diagnosis 2Health News:Parents are More Concerned on What Their Kids Watch 2Health News:New Device Developed to Eliminate Superbugs Within Minutes 2Health News:Two, Not One Networks Rule Brain's Voluntary Chain-of-command 2Health News:Two, Not One Networks Rule Brain's Voluntary Chain-of-command 3Health News:China Cannot Be Blamed for Rising CO2 Emissions: Britain Official 2
... plates in mind, Pipetman Ultra Multichannel ... applications: PCR* sequencing, immunology assays, series ... with Diamond Tips from Gilson's patented ... maximize performance and assure productivity.,* PCR ...
... variety of applications. • Whole pipette is autoclavable ... rotated against the handle to work in a ... towards the microtiter plate. • The special nose ... pipette tips, and provides a firm, parallel fit. ...
... precision, ergonomics, and value!, Comfortable feel ... contoured handle , Finer control while pipetting ... Stress-free tip ejection with long, lever tip ... and sterilization without the need for recalibration ...
... precision, ergonomics, and value!, Comfortable feel ... contoured handle , Finer control while pipetting ... Stress-free tip ejection with long, lever tip ... and sterilization without the need for recalibration ...
Medicine Products: