Navigation Links
New Data From Phase 3 Study Suggests Tapentadol Immediate Release Effective for Acute Pain From Common Foot Surgery
Date:5/9/2008

a(TM), Division of Ortho-McNeil-Janssen Pharmaceuticals, Inc., will market tapentadol in the United States. The NDA filing is part of the ongoing commitment of J&JPRD and PriCara(TM) to bring new and innovative products to patients and physicians for the treatment and management of pain.

Study Design

This Phase 3, double-blind, randomized, multi-center trial examined the efficacy, safety and tolerability of multiple doses of tapentadol IR in 603 post-surgical bunionectomy patients. Participants were randomly assigned (1:1:1:1:1) to receive tapentadol IR 50, 75, or 100 mg, oxycodone 15 mg, or placebo and the primary efficacy endpoint was the sum of their pain intensity differences at 48 hours. Secondary endpoints included sum of pain intensity differences at 12, 24, and 72 hours.

J&JPRD and Grunenthal GmbH supported this study.

J&JPRD and Ortho-McNeil-Janssen Pharmaceuticals, Inc. are wholly owned subsidiaries of Johnson & Johnson.

Johnson & Johnson Pharmaceutical Research & Development, L.L.C.

Johnson & Johnson Pharmaceutical Research & Development, L.L.C., (J&JPRD) is a wholly owned subsidiary of Johnson & Johnson, the world's most broadly based producer of health care products. J&JPRD is headquartered in Raritan, N.J., and has facilities throughout Europe, the United States and Asia. J&JPRD is leveraging drug discovery and drug development in a variety of therapeutic areas, including CNS, Internal Medicine and Oncology, to address unmet medical needs worldwide. More information can be found at http://www.jnjpharmarnd.com/.

PriCara(TM), Division of Ortho-McNeil-Janssen Pharmaceuticals, Inc.

PriCara(TM), a Division of Ortho-McNeil-Janssen Pharmaceuticals, Inc., is a major health care company in the United States dedicated to the needs of primary care providers who serve a vital role on the frontline of medicine. For more information about the co
'/>"/>

SOURCE Johnson & Johnson Pharmaceutical Research & Development,L.L.C.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Dendreon Announces Publication of Phase 1 Study Highlighting Immunologic and Clinical Activity of Lapuleucel-T (Neuvenge(R)) in Advanced Breast Cancer Patients
2. Thomson Scientific Publishes The Ones to Watch - A Quarterly Review of Phase Changes in the Pharmaceutical Pipeline
3. Progen Engages Leading CRO to Assist with Phase 3 Trial of PI-88
4. The Multiple Myeloma Research Consortium (MMRC) and Proteolix Initiate Phase 2 Clinical Trial Investigating Carfilzomib for the Treatment of Multiple Myeloma
5. Vion Pharmaceuticals Completes Accrual of 85 Patients to its Pivotal Phase II Trial of Cloretazine(R) (VNP40101M) in Elderly AML
6. Multiple Myeloma Research Consortium (MMRC) Partners with Novartis to Advance Phase II Study of Deacetylase Inhibitor
7. Positive Kuvan(TM) Pivotal Phase 3 Trial Results Published in The Lancet
8. Potential Safety Issue Identified in Ongoing Phase 2 Clinical Study of HCV-796
9. TaiGen Biotechnology Successfully Completes Patient Recruitment for Phase II Trial of Nemonoxacin for Treatment of Adult Community Acquired Pneumonia (CAP)
10. DOV Pharmaceutical, Inc. Announces Successful Phase Ib Results for DOV 21,947
11. Callisto Pharmaceuticals Opens Additional Sites for Phase II Clinical Trial of Atiprimod in Advanced Carcinoid Cancer Patients
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/28/2014)... 28, 2014  Some 2,500 scientists and experts from ... Montreal for the largest international meeting ... that draws researchers from fields as far flung as ... as designing new manufacturing processes to creating life-saving drugs. ... because the United Nations has declared 2014 the International ...
(Date:7/28/2014)... 2014  Surgical Theater, LLC announced today the ... Advisory Board. New members include Ori J. ... Development and New Technologies for Given Imaging Ltd., ... Vice President and General Manager of Philips Healthcare,s ... simulation technology to brain surgery and has developed ...
(Date:7/28/2014)... 28, 2014  Air Products (NYSE: APD ... oxygen is vital to any healthcare facility. This understanding ... only improve the efficiency of its oxygen supply systems, ... these systems—including systems for emergency oxygen supply ... 4-5 at the 51 st ASHE Annual ...
Breaking Medicine Technology:All About Crystals: Tiny, Giant, from Mars, from Earth's Mantle, in Medicine and in Manufacturing 2All About Crystals: Tiny, Giant, from Mars, from Earth's Mantle, in Medicine and in Manufacturing 3All About Crystals: Tiny, Giant, from Mars, from Earth's Mantle, in Medicine and in Manufacturing 4All About Crystals: Tiny, Giant, from Mars, from Earth's Mantle, in Medicine and in Manufacturing 5All About Crystals: Tiny, Giant, from Mars, from Earth's Mantle, in Medicine and in Manufacturing 6Surgical Theater Names Former Given Imaging Ltd. and Philips Healthcare Executives to Business Advisory Board 2Surgical Theater Names Former Given Imaging Ltd. and Philips Healthcare Executives to Business Advisory Board 3Surgical Theater Names Former Given Imaging Ltd. and Philips Healthcare Executives to Business Advisory Board 4Surgical Theater Names Former Given Imaging Ltd. and Philips Healthcare Executives to Business Advisory Board 5Air Products Highlights Its Medical Oxygen Supply Systems for Emergency Oxygen Supply and Reduced Oxygen Loss at ASHE 2Air Products Highlights Its Medical Oxygen Supply Systems for Emergency Oxygen Supply and Reduced Oxygen Loss at ASHE 3
... event today on Capitol Hill, the Global Fund ... of the Global Fight Against AIDS, Tuberculosis and ... the Global Fund,s lifesaving work. From assistance in ... consumer markets, to in-country partnerships, Chevron, The Coca-Cola ...
... 20, 2012 The March of Dimes announced today that ... 2012 March for Babies, the March of Dimes number one ... the Prematurity Campaign.  Together, the organizations will also work to ... "Watson employees are participating in March for Babies events ...
Cached Medicine Technology:Global Fund Celebrates Efforts of Partners Chevron, The Coca-Cola Company, (RED) and PEPFAR at Capitol Hill Event 2Global Fund Celebrates Efforts of Partners Chevron, The Coca-Cola Company, (RED) and PEPFAR at Capitol Hill Event 3Global Fund Celebrates Efforts of Partners Chevron, The Coca-Cola Company, (RED) and PEPFAR at Capitol Hill Event 4Watson Partners With March of Dimes to Help Fight Preterm Birth 2
(Date:7/28/2014)... cells do not divide unless there is enough oxygen ... and other cell types circumvent this rule. Researchers at ... that overrides the cells, warning signals, enabling cancers to ... In the process, the researchers found that lysosomes ... division decisions. They also uncovered new evidence that certain ...
(Date:7/28/2014)... 2014 The Brooke Jackman Foundation ... more than 200,000 books to children and families in ... of Brooke’s Cooks, a new initiative designed to promote ... among at-risk children and their families in the New ... of nutrition information workshops, cooking demonstrations and readings. BJF, ...
(Date:7/28/2014)... of two dopamine-producing regions in the brain was able ... or propofol. In the August issue of ... that rats anesthetized with continuous doses of either agent ... in response to electrical stimulation delivered to the ventral ... dopamine-releasing area, the substantia nigra, did not induce the ...
(Date:7/28/2014)... (PRWEB) July 28, 2014 Sarasota-based FCCI ... Best Companies To Work For. Still headquartered in Sarasota ... the only Florida-domiciled company in the top ten of ... Companies list appears in the August issue of Florida ... and large employer categories. Ranked #7 for 2014, FCCI ...
(Date:7/28/2014)... BEER-SHEVA, ISRAEL, July 28, 2014...Mothers who live near ... weights, according to a new study, "Green Spaces ... Occupational and Environmental Medicine . , A ... Ben-Gurion University of the Negev (BGU), evaluated nearly ... cohort in Tel Aviv, Israel to determine the ...
Breaking Medicine News(10 mins):Health News:Cell's recycling center implicated in division decisions 2Health News:Brooke Jackman Foundation Launches Brooke's Cooks, New Initiative to Promote Healthy Living Among At-Risk Youth and Their Families 2Health News:Brooke Jackman Foundation Launches Brooke's Cooks, New Initiative to Promote Healthy Living Among At-Risk Youth and Their Families 3Health News:Brooke Jackman Foundation Launches Brooke's Cooks, New Initiative to Promote Healthy Living Among At-Risk Youth and Their Families 4Health News:Stimulation of brain region restores consciousness to animals under general anesthesia 2Health News:FCCI Insurance Group Makes Top 100 Best Companies List – and is the Only Florida-Headquartered Company in Top Ten 2Health News:FCCI Insurance Group Makes Top 100 Best Companies List – and is the Only Florida-Headquartered Company in Top Ten 3
... 25 The Akron General Health System, a,nationally ... and,wellness, is accepting nominations for its second annual ... individuals and,corporations/organization -- throughout the State of Ohio ... or the health of their,employees., Nominations for ...
... know that there,s a new infant formula that blocks ... Vitamin D status during pregnancy will affect her baby,s ... syrup that prevents early-childhood tooth decay? ,These are but ... which will be presented when the International,Association for Dental ...
... Viral video communicates the importance of skin cancer ... Neutrogena(R) Partnership for,Skin Health, a public service initiative ... advancements and explore solutions for,skin health, has tapped ... video about self-examination for skin cancer detection. As ...
... National Association of Health Care Assistants Delivers Letter ... to Seniors, Nursing Home,Care, JOPLIN, Mo., June ... (NAHCA) -- representing the voice of,more than 20,000 ... 29 states and,the District of Columbia -- delivered ...
... in German . , Oregano doesnt only ... and the ETH Zrich have discovered that this spice also ... cure inflammations. The researchers administered its active ingredient known ... seven out of ten cases there was a subsequent improvement ...
... is a national concern that led the U.S. surgeon ... and Reduce Underage Drinking" ( http://www.surgeongeneral.gov/topics/underagedrinking/ ) last year. ... researcher assesses the effectiveness of underage drinking prevention programs ... key goals outlined by the surgeon general. , Lead ...
Cached Medicine News:Health News:Statewide Wellness Awards Competition Now Open for Nominations 2Health News:International Dental Research Association meets in Toronto 2Health News:International Dental Research Association meets in Toronto 3Health News:International Dental Research Association meets in Toronto 4Health News:Neutrogena(R) Partnership For Skin Health Taps Malin Akerman to Educate About Skin Cancer Detection 2Health News:Neutrogena(R) Partnership For Skin Health Taps Malin Akerman to Educate About Skin Cancer Detection 3Health News:Nation's Health Care and Nursing Assistants Urge HHS to Withdraw Proposed $770 Million Funding Cut to Skilled Nursing Care 2Health News:Salutary pizza spice 2Health News:Pediatrics review of underage drinking prevention programs led by Iowa State researcher 2Health News:Pediatrics review of underage drinking prevention programs led by Iowa State researcher 3
... Diagnostics is a leading provider of immunofluorescence ... test menu that includes kits for autoimmune ... as miscellaneous conjugates and components. Our Impact ... assortment of substrates and kit sizes to ...
... Professional Diagnostics is a leading provider of ... DFA test menu that includes kits for ... well as miscellaneous conjugates and components. Our ... wide assortment of substrates and kit sizes ...
... Inverness Medical Professional Diagnostics is a leading ... IFA and DFA test menu that includes ... STDs as well as miscellaneous conjugates and ... you a wide assortment of substrates and ...
... infectious disease ELISA products make us a ... protocols for faster integration into the busy ... increased reliability and run-to-run consistency. Our Infectious ... for a wide range of serological assays ...
Medicine Products: