Navigation Links
New Data From Phase 3 Study Suggests Tapentadol Immediate Release Effective for Acute Pain From Common Foot Surgery
Date:5/9/2008

Novel Pain Medicine Studied in Patients Following Bunionectomy

TAMPA, Fla., May 9 /PRNewswire-USNewswire/ -- Many foot-surgery patients experience intense pain for several days following removal of a bunion, one of the most common foot surgeries. The investigational pain medication tapentadol provided significant relief for patients who had this surgery, compared to those treated with placebo. Treatment with tapentadol also resulted in patients reporting fewer gastrointestinal side effects compared to those treated with an older, prescription pain reliever, researchers announced today.

Results from a Phase 3 clinical study of tapentadol immediate release (IR) tablets, a novel, investigational, centrally acting oral analgesic, showed that patients receiving 50 mg, 75 mg, or 100 mg of the medication experienced significant relief in acute pain after bunionectomy, a standard foot surgery associated with predictable levels of moderate to severe pain.

The overall difference in the intensity of pain experienced by patients recovering from bunionectomy was examined over the first 12, 24, 48 and 72 hours after initiating treatment with tapentadol. All tapentadol IR treatment groups showed a statistically significant improvement in pain over patients who received placebo, over all of these time periods (P<0.001).

Johnson & Johnson Pharmaceutical Research & Development, L.L.C. (J&JPRD) presented these new data in a poster session at the 27th Annual Scientific Meeting of the American Pain Society (APS) in Tampa, Florida.

Treatment with 100 mg of tapentadol IR resulted in 79 percent of patients experiencing at least a 30 percent improvement in pain intensity at 48 hours. This is comparable to the 78 percent of patients who experienced the same percentage of improvement with 15 mg of oxycodone IR. Compared with placebo, the incidence of adverse events was higher for tapentadol IR and oxycodone IR treatment groups with a dose-
'/>"/>

SOURCE Johnson & Johnson Pharmaceutical Research & Development,L.L.C.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Dendreon Announces Publication of Phase 1 Study Highlighting Immunologic and Clinical Activity of Lapuleucel-T (Neuvenge(R)) in Advanced Breast Cancer Patients
2. Thomson Scientific Publishes The Ones to Watch - A Quarterly Review of Phase Changes in the Pharmaceutical Pipeline
3. Progen Engages Leading CRO to Assist with Phase 3 Trial of PI-88
4. The Multiple Myeloma Research Consortium (MMRC) and Proteolix Initiate Phase 2 Clinical Trial Investigating Carfilzomib for the Treatment of Multiple Myeloma
5. Vion Pharmaceuticals Completes Accrual of 85 Patients to its Pivotal Phase II Trial of Cloretazine(R) (VNP40101M) in Elderly AML
6. Multiple Myeloma Research Consortium (MMRC) Partners with Novartis to Advance Phase II Study of Deacetylase Inhibitor
7. Positive Kuvan(TM) Pivotal Phase 3 Trial Results Published in The Lancet
8. Potential Safety Issue Identified in Ongoing Phase 2 Clinical Study of HCV-796
9. TaiGen Biotechnology Successfully Completes Patient Recruitment for Phase II Trial of Nemonoxacin for Treatment of Adult Community Acquired Pneumonia (CAP)
10. DOV Pharmaceutical, Inc. Announces Successful Phase Ib Results for DOV 21,947
11. Callisto Pharmaceuticals Opens Additional Sites for Phase II Clinical Trial of Atiprimod in Advanced Carcinoid Cancer Patients
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/23/2014)... DUBLIN , Sept. 23, 2014 /PRNewswire/ ... "Company"), a biotechnology company pioneering the manufacturing and ... emerging nations, today announced that the Depository Trust ... DTC,s Deposit and Withdrawal at Custodian ("DWAC") service ... transfer agent as the distribution point.  The Company,s ...
(Date:9/23/2014)... -- This test can detect HIV infection if used 3 ... activities that can transfer body fluids from one person to ... needles. , An in-vitro diagnostic home-use test for ... works by looking for your body,s response to fighting the ... patients to learn their status in a single visit and ...
(Date:9/23/2014)... DUBLIN , September 23, 2014 /PRNewswire/ ... ) has announced the addition of the  ...  report to their offering.  ... injectable drug delivery market holds significant potential ... with vials and painful needles to the ...
Breaking Medicine Technology:TNI BioTech, Inc. Announces Its Stock is Now DTC DWAC/FAST Eligible 2TNI BioTech, Inc. Announces Its Stock is Now DTC DWAC/FAST Eligible 3TNI BioTech, Inc. Announces Its Stock is Now DTC DWAC/FAST Eligible 4WholeHealth Products announces the release of the FDA Cleared "HIV 1&2" Rapid Diagnostic Test for Professional and Retail 2Large Volume Wearable Injectors - 2nd Edition 2Large Volume Wearable Injectors - 2nd Edition 3Large Volume Wearable Injectors - 2nd Edition 4Large Volume Wearable Injectors - 2nd Edition 5
... N.J.--(BUSINESS WIRE)--Jun 21, 2007 - Nymox,Pharmaceutical Corporation ... the Company's recently completed studies of,NX-1207 for ... at,a series of upcoming U.S. urology meetings, ... Urological Association Meeting in,Colorado Springs. These independent ...
... June 21, 2007 /PRNewswire/ -- , What and When , Data ... presented in poster format at the 67th,Scientific Sessions of the American ... serious adverse events in high-risk type 2, ... from, PROactive; Poster 0553-P presented ...
Cached Medicine Technology:Nymox Announces NX-1207 Data to Be Presented at Upcoming U.S.,Urology Meetings 2MEDIA ADVISORY: Subsets of Landmark Diabetes Trials Investigating,MacroVascular Outcomes Presented at the American Diabetes,Association 67th Scientific Sessions 2MEDIA ADVISORY: Subsets of Landmark Diabetes Trials Investigating,MacroVascular Outcomes Presented at the American Diabetes,Association 67th Scientific Sessions 3
(Date:9/23/2014)... Doheny HealthDay Reporter TUESDAY, ... very low birth weights, breast milk is more likely than ... known as cytomegalovirus (CMV), a new study finds. The ... -- all of whom weighed 3.3 pounds or less and ... CMV infection, to see whether breast milk or transfusions carried ...
(Date:9/23/2014)... drinking and getting drunk at an early age are ... students, a new study suggests. The conclusions, based ... could help expand alcohol-prevention efforts aimed at teens to ... becoming binge drinkers, the researchers suggested. , , "Efforts ... progression to first heavy use as risk factors for ...
(Date:9/23/2014)... What information do patients need ... Forum (NQF) released a report ( http://bit.ly/1DwekE9 ), ... infographic ( http://bit.ly/1tX3lzA ) resulting from an in-depth ... patients define affordability, and what information and changes ... possible healthcare at the lowest possible cost. ...
(Date:9/23/2014)... 23, 2014 (HealthDay News) -- Few children ... undergo behavioral therapy, and the rates vary six-fold ... study finds. Medication alone can manage symptoms ... better if they also receive behavioral therapy (psychotherapy), ... analyzed data in more than 1,500 counties across ...
(Date:9/23/2014)... grow up to earn up to 18 percent less ... Lundborg of Lund University, Paul Nystedt of Jnkping University ... all in Sweden. The team compared extensive information from ... the results are published in Springer,s journal Demography ... 145,193 Swedish-born brothers who enlisted in the Swedish National ...
Breaking Medicine News(10 mins):Health News:Breast Milk a Risk for Spreading Common Virus to Preemies, Study Finds 2Health News:Breast Milk a Risk for Spreading Common Virus to Preemies, Study Finds 3Health News:Younger Age at First Drink, Higher Odds for Problem Drinking: Study 2Health News:Younger Age at First Drink, Higher Odds for Problem Drinking: Study 3Health News:Finding Affordable Care: Asking the Right Question is Key 2Health News:Kids Taking ADHD Drugs Get Little Psychotherapy: Study 2Health News:Note to young men: Fat doesn't pay 2
... evidence of the damaging impact of marijuana on humans ... symptoms in some people, including hallucinations and paranoid delusions, ... recent study, one compound, cannabidiol, or CBD, made people ... tetrahydrocannabinol, or THC, produced temporary psychotic symptoms in people, ...
... victims of a bite from the Brazilian wandering spider (Phoneutria ... in blood pressure, they also sport an uncomfortable erection. ,And ... Viagras. Scientists say they have figured out the chemical that ... , “The erection is a side effect that everybody who ...
... healthcare scheme proposed by the Australian Federal government. The ... people to opt for private health insurance; yet this plan ... by public hospital, a report has shown. ,Dr ... Research on Health, explained the benefits of doing away with ...
... affect people of all ages. The general public is at ... instruction on ladder use and safety. ,According to ... Journal of Preventive Medicine and conducted by the Center for ... than 2.1 million individuals were treated in U.S. emergency departments ...
... suffer migraine attacks, beware. Recent research has shown the ... depression and suicidal tendencies. They could also be suffering ... ,Teens suffering migraines are prone to depressive tendencies ... such agonizing headaches, a new study has shown. ...
... homes have started coming to the fore. One among fifty ... review by the Department of Ageing, Disability and Home Care, ... involving abuse and lack of care. The main cause was ... carers. ,Advocates nationwide say it is a growing problem ...
Cached Medicine News:Health News:Marijuana can Trigger Psychotic Symptoms, New Study Finds 2Health News:Brazil Spider Offers Hope for Those Suffering from Erectile Dysfunction 2Health News:$3bn Rebate Scheme – Is Australia Making a Prudent Move 2Health News:Ladder-related Injuries on the Rise in U.S 2Health News:Link Between Migraine Attacks in Teens and Suicidal Tendencies 2Health News:Abuse of the Disabled in Government Run Homes 2
... A fixed pipette is ... a single volume. Fixed volume ... and advantages as other Finnpipette ... design, Super blow-out (1-40ul), Soft-touch ...
... The Research Family includes fixed-volume, ... as the electronic Eppendorf Research pro ... button, these compact, high-performance pipettes have ... Optimally suited for use with original ...
10L...
... fixed pipette is ideal for ... volume. Fixed volume FInnpipettes offer ... as other Finnpipette Digital pipettes: ... blow-out (1-40ul), Soft-touch tip ejection, ...
Medicine Products: