Navigation Links
New Data Examines the Effect of Adding a Statin to Optimized Treatment for Patients with Advanced Heart Failure
Date:11/5/2007

ORLANDO, Fla., Nov. 5 /PRNewswire-FirstCall/ -- New data from the CORONA study presented today at the American Heart Association 2007 Scientific Sessions showed that adding a statin to optimized heart failure treatment did not significantly improve the prognosis for patients with advanced heart failure because it could not reverse or prevent the deterioration of a failing heart.

Patients taking AstraZeneca's CRESTOR(R) (rosuvastatin calcium) 10 mg experienced an 8 percent reduction in the combined primary endpoint of cardiovascular death, myocardial infarction or stroke, which was not statistically significant (p=0.12). This reduction was primarily driven by a decrease in atherosclerotic events, i.e. stroke and myocardial infarctions (post hoc analysis, nominal p=0.05), where statins have been proven to have benefit. In this study the majority of deaths were due to sudden death, or non-ischemic causes, which did not appear to be impacted by statin therapy. In addition, significantly fewer hospitalizations occurred in patients on CRESTOR compared to placebo, whether due to any cause (p=0.007), cardiovascular causes (p<0.001), or for worsening heart failure (p=0.01).

"The CORONA results represent a major advancement in medical research and understanding of patients with advanced heart failure, as it appears they clearly differ from patients without heart failure in their response to statin treatment," said lead investigator Prof. John Kjekshus, Department of Cardiology, Rikshospitalet University Hospital, Oslo, Norway. "We added a highly effective statin on top of an optimal treatment regimen. Our findings suggest the major cause of death in these patients was likely not to be related to atherosclerotic events, where benefit with statins in non-heart failure patients has been demonstrated, but instead may have been caused by the deterioration of failing heart muscle damaged beyond repair. CORONA underscores the need for early intervention in the pro
'/>"/>

SOURCE AstraZeneca
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. AAHC Examines Nations Clinical Trials Infrastructure
2. Endoscopy Identified as Safe and Effective Method in Treating Common Complication of Gastric Bypass Surgery
3. Clinical Trial Effectiveness: How Pharmas & Biotechs Save Cost with Savvy Investigator Management
4. DNA Test Predicts Harmful Effects of Cancer Drug
5. New Risk Gene for Rheumatoid Arthritis and Lupus Opens Door to More Effective Treatments
6. Rochester Medical Anti-Infection Foley Catheter Demonstrates Effectiveness in Randomized Trial
7. New Data Show Doripenem as Effective as Commonly Used Therapies in Treating Hospital-Acquired Pneumonias
8. Tablet PC Technology Helps Doctors and Patients Focus on Chemotherapy Side Effects, According to Thomson Healthcare Study
9. New Data Show Ceftobiprole as Effective as Combination Therapy in Treating Patients With Complicated Skin Infections, Including MRSA
10. ECLIPSE Data on Effects of Otsukas Investigational Novel Treatment, Tolvaptan, on Advanced Heart Failure Patients Hemodynamics and Urine Output Featured in Heart Failure Society of Americas Late Breaking Trials
11. New Topical Therapy Safely Treats Serious Skin Infections Without Systemic Side Effects
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/3/2015)... NEWS, Va. , Aug. 3, 2015 /PRNewswire/ ... be joining Orthopaedic & Spine Center ... them to manage their chronic pain through psychological ... Robinson is a Fellowship-trained, certified medical psychologist ... pain medicine. His vast experience ranges from assessment ...
(Date:8/3/2015)... , Aug. 3, 2015  BioElectronics Corporation (OTC Pink: ... management, announced that Andrew J. Whelan , President ... his program "On Business" at 9am EDT on Wednesday, ... live, tune to: http://tunein.com/radio/Money-Matters-Boston-1120-s27548/ ... the exceptional acceptance the company,s flagship product, ActiPatch Therapy, ...
(Date:8/3/2015)... , Aug. 3, 2015  CytomX, a biopharmaceutical ... cancer, today announced the promotion of several members ... Ray , who previously served as vice president ... promoted to senior vice president of corporate development ... held positions as the vice president of business ...
Breaking Medicine Technology:Orthopaedic & Spine Center Introduces New Pain Psychologist 2UpTick News Wire Radio Show Will Interview BioElectronics' CEO Andrew Whelan 2CytomX Announces Management Team Promotions 2CytomX Announces Management Team Promotions 3
... Radioactive Microspheres in... -- ROME, August 19, 2010 ... ... ... Results are keyed by longUrl, so we need to grab the first one. for (var r ...
... Reportlinker.com announces that a new market research ... Advances in Large Scale BioManufacturing and Scale-Up ... A Comprehensive Study of ... This new ASM study provides a clear view ...
Cached Medicine Technology:Multi-centre Phase II Trial Reports Safety and Clinical Benefits of Radioactive Microspheres in Patients with Colorectal Cancer Liver Metastases who have Failed Chemotherapy 2Multi-centre Phase II Trial Reports Safety and Clinical Benefits of Radioactive Microspheres in Patients with Colorectal Cancer Liver Metastases who have Failed Chemotherapy 3Multi-centre Phase II Trial Reports Safety and Clinical Benefits of Radioactive Microspheres in Patients with Colorectal Cancer Liver Metastases who have Failed Chemotherapy 4Multi-centre Phase II Trial Reports Safety and Clinical Benefits of Radioactive Microspheres in Patients with Colorectal Cancer Liver Metastases who have Failed Chemotherapy 5Multi-centre Phase II Trial Reports Safety and Clinical Benefits of Radioactive Microspheres in Patients with Colorectal Cancer Liver Metastases who have Failed Chemotherapy 6Multi-centre Phase II Trial Reports Safety and Clinical Benefits of Radioactive Microspheres in Patients with Colorectal Cancer Liver Metastases who have Failed Chemotherapy 7Multi-centre Phase II Trial Reports Safety and Clinical Benefits of Radioactive Microspheres in Patients with Colorectal Cancer Liver Metastases who have Failed Chemotherapy 8Multi-centre Phase II Trial Reports Safety and Clinical Benefits of Radioactive Microspheres in Patients with Colorectal Cancer Liver Metastases who have Failed Chemotherapy 9Reportlinker Adds Advances in Large Scale BioManufacturing and Scale-Up Production, 2nd ED 2Reportlinker Adds Advances in Large Scale BioManufacturing and Scale-Up Production, 2nd ED 3
(Date:8/4/2015)... ... August 04, 2015 , ... The Law Offices of ... device lawsuit claims dealing with Inferior Vena Cava Filters (“IVC Filters”). , As lead ... cases for Cook IVC Filter clients under In re Cook Medical, Inc., IVC Filters ...
(Date:8/4/2015)... ... August 04, 2015 , ... In ... filed against Johnson & Johnson report that a new location for pretrial proceedings ... regular news updates and cancer warning information at their website, the Talcum Powder ...
(Date:8/4/2015)... ... 04, 2015 , ... Continuing Education Company (CEC) ... interaction simulation session entitled "NOACS: What the Evidence Shows in Managing AFib, ... Inc. and EDUmotion US LLC. , This special activity was recently presented during ...
(Date:8/4/2015)... ... 04, 2015 , ... Lightning Labels is pleased to announce ... will usher in a new standard of sticker and label-making for the company. ... its twin objectives of quality and quantity without compromising the signature lightning-fast speed ...
(Date:8/4/2015)... ... August 04, 2015 , ... ... results have been impressive so far". , Mr Cauchois attributes the success ... French sales partner Dicma and the healthcare technology offered by Winscribe's platform. ...
Breaking Medicine News(10 mins):Health News:Law Offices of Ben C. Martin in Dallas Files New IVC Filter Complications Lawsuits and Pursues Settlements 2Health News:Law Offices of Ben C. Martin in Dallas Files New IVC Filter Complications Lawsuits and Pursues Settlements 3Health News:Talcum Powder Lawsuits: Plaintiffs Suggest Middlesex County Transfer 2Health News:Talcum Powder Lawsuits: Plaintiffs Suggest Middlesex County Transfer 3Health News:Talcum Powder Lawsuits: Plaintiffs Suggest Middlesex County Transfer 4Health News:Innovative Medical Interactive Simulation Session to be presented at upcoming Continuing Education Company Education (CME) Conferences. 2Health News:Innovative Medical Interactive Simulation Session to be presented at upcoming Continuing Education Company Education (CME) Conferences. 3Health News:Lightning Labels Installs State-of-the-Art Digital Press 2Health News:Lightning Labels Installs State-of-the-Art Digital Press 3Health News:The Oscar Lambret Center (France) Completes First Stage Of Winscribe Text Rollout 2Health News:The Oscar Lambret Center (France) Completes First Stage Of Winscribe Text Rollout 3Health News:The Oscar Lambret Center (France) Completes First Stage Of Winscribe Text Rollout 4
... appearance of a cold sore is,a sign that your ... emerge, according to John Sherman, ND, noted naturopathic,physician and ... 80% and 90% of the adult population have the ... Dr. Sherman, who,is the author of The Complete Botanical ...
... Patient safety incidents cost the federal Medicare ... preventable deaths during 2004 through 2006, according to ... Study. HealthGrades, analysis of 41 million Medicare patient ... had, on average, a 43 percent lower chance ...
... WALTHAM, Mass., April 7, 2008 Repligen,Corporation (Nasdaq: ... and,Chief Executive Officer, Walter C. Herlihy, Ph.D., will host ... at 9:00 a.m. EDT, to provide,an update on the ... Thomson/CCBN and can be accessed via,Repligen,s website at ...
... from China is no cause for alarm , , MONDAY, ... probable case of human-to-human transmission of bird flu in ... that there,s a genetic component to human-to-human transmission of ... "This suggests that there,s some genetic component to resistance ...
... ALB ) will hold its quarterly conference call to ... ET., This call is being webcast by Thomson/CCBN and ... in the Investor,Information section., To listen ... In # 800-591-6942 International Dial In ...
... April 7, 2008 American Media, Inc. (AMI),today ... corporate website certain,information currently required to be disclosed ... its amended Senior Secured Credit Agreement., The ... certain key magazine titles during the period April ...
Cached Medicine News:Health News:A Cold Sore Is Often A Warning Sign of Deeper Health Issues, Expert Says 2Health News:Medical errors cost US $8.8B, result in 238,337 potentially preventable deaths: HealthGrades study 2Health News:Medical errors cost US $8.8B, result in 238,337 potentially preventable deaths: HealthGrades study 3Health News:Medical errors cost US $8.8B, result in 238,337 potentially preventable deaths: HealthGrades study 4Health News:Repligen Announces Conference Call to Update Orencia(R) Lawsuit 2Health News:Repligen Announces Conference Call to Update Orencia(R) Lawsuit 3Health News:Probable Case of Human-to-Human Bird Flu Transmission Reported 2Health News:Probable Case of Human-to-Human Bird Flu Transmission Reported 3Health News:Albemarle Corporation's First Quarter 2008 Earnings Conference Call To Be Held April 22, 2008 at 8:00am ET 2
... This therapeutic system is ... patient in mind. As ... and ongoing therapy, SONOCUR ... and effective therapy. Plus, ...
All the power and performance of the STS - T but now available with a stand-alone 9" II C-Arm...
... only one of the most modern lithotripters available ... from being designed for the treatment of the ... the MODULITH SLX can also be employed for ... equally suitable for the treatment of gallstones or ...
... The MINILITH SL1 developed by STORZ MEDICAL ... extensive experience in the field of kidney ... the specific requirements to be met by ... as has been outlined above. The MINILITH ...
Medicine Products: