Navigation Links
New Data Detailing Economic Impact of IV Acetaminophen in Treating Acute Pain to be Presented at Two Major Healthcare Conferences
Date:12/9/2013

ORLANDO, Fla., Dec. 9, 2013 /PRNewswire/ -- Cadence Pharmaceuticals, Inc. (NASDAQ: CADX), a biopharmaceutical company focused on acquiring, in-licensing, developing and commercializing proprietary products principally for use in the hospital setting, announced today that results from a new study analyzing large-scale hospital billing data will be presented today at two major healthcare conferences.  The study examined the impact of Cadence's IV acetaminophen therapy, OFIRMEV® (acetaminophen) injection, on certain healthcare-related outcomes in the perioperative setting.  The data from this study will be presented in Orlando, Florida, at the American Society of Health-System Pharmacists (ASHP) Midyear Clinical Meeting and at the Institute for Health Improvement (IHI) National Forum.

The study evaluated data from more than 22,000 inpatient admissions for major joint repair procedures from a hospital research database of more than 550 hospitals maintained by the Premier healthcare alliance.  In the analysis, 11,073 patients who underwent elective major joint arthroplasty and who received OFIRMEV on the day of surgery were matched to 11,073 patients who did not receive the treatment during their stay.  Researchers compared data from the two groups to assess differences in certain patient outcomes, including hospital length-of-stay, and average hospital costs.

"This research is very encouraging and demonstrates how integrating IV acetaminophen as a foundation for multimodal surgical analgesia may positively impact the cost of care and outcomes for surgical patients," said Ted Schroeder, President and CEO of Cadence.  "Multiple medical societies have endorsed multimodal analgesia to optimize pain outcomes while reducing opioid use in order to minimize side effects often seen with narcotics.  We look forward to working with medical professionals to help implement multimodal treatment strategies."

About the data
Evaluation of Patient Outcomes, Length of Stay, and Average Hospital Costs with IV Acetaminophen: A Case-Matched Analysis of a National Inpatient Hospital Database. Christian Apfel, M.D., Ph.D., Adjunct Associate Professor, Department of Epidemiology and Biostatistics, UCSF, San Francisco, CA. (ASHP abstract 3-127)

Effect of IV acetaminophen on Postoperative Outcomes, Length of Stay and Costs: National Hospital Database Analysis of 11,073 Matched Pairs. Presenter: Gary Oderda, Pharm.D., M.P.H., Professor, Director, Pharmaceutical Outcomes Research Center, University of Utah College of Pharmacy, Salt Lake City, UT. (IHI poster 32)

About OFIRMEV® (Acetaminophen) Injection
OFIRMEV (acetaminophen) injection (1000 mg / 100 mL, 10 mg / mL; for intravenous use only), Cadence Pharmaceuticals' proprietary intravenous formulation of acetaminophen, is indicated for the management of mild to moderate pain, the management of moderate to severe pain with adjunctive opioid analgesics, and the reduction of fever. The effectiveness of OFIRMEV for the treatment of acute pain and fever has not been studied in pediatric patients less than 2 years of age.

Important Safety Information
RISK OF MEDICATION ERRORS AND HEPATOTOXICITY

Take care when prescribing, preparing, and administering OFIRMEV injection to avoid dosing errors which could result in accidental overdose and death.

OFIRMEV contains acetaminophen.  Acetaminophen has been associated with cases of acute liver failure, at times resulting in liver transplant and death.  Most of the cases of liver injury are associated with the use of acetaminophen at doses that exceed the recommended maximum daily limits, and often involve more than one acetaminophen-containing product.

OFIRMEV is contraindicated in patients with severe hepatic impairment, severe active liver disease or with known hypersensitivity to acetaminophen or to any of the excipients in the formulation.  Acetaminophen should be used with caution in patients with the following conditions: hepatic impairment or active hepatic disease, alcoholism, chronic malnutrition, severe hypovolemia, or severe renal impairment. Rarely, acetaminophen may cause serious skin reactions such as acute generalized exanthematous pustulosis (AGEP), Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis (TEN), which can be fatal.  Discontinue OFIRMEV immediately if symptoms associated with allergy or hypersensitivity occur, or at the first appearance of skin rash. Do not use in patients with acetaminophen allergy.

The most common adverse reactions in patients treated with OFIRMEV were nausea, vomiting, headache, and insomnia in adult patients and nausea, vomiting, constipation, pruritus, agitation, and atelectasis in pediatric patients. The antipyretic effects of OFIRMEV may mask fever in patients treated with postsurgical pain. Do not exceed the recommended maximum daily dose of OFIRMEV. OFIRMEV should be administered only as a 15-minute infusion.

For more information, please see the full OFIRMEV Prescribing Information, including the complete boxed warning, which is available at www.OFIRMEV.com or www.cadencepharm.com.

About Cadence Pharmaceuticals, Inc.
Cadence Pharmaceuticals is a pharmaceutical company focused on acquiring, in-licensing, developing and commercializing proprietary products principally for use in the hospital setting.  OFIRMEV® was approved by the FDA in November 2010, launched in early 2011, and is now used in over 4,600 hospitals nationwide with an estimated 5.5-6.9 million hospitalized patients treated through October 31, 2013, based on an estimate of 2-2.5 doses per patient. The current version of Cadence Pharmaceuticals' corporate overview may be viewed on the Investors page of www.cadencepharm.com under "Events & Presentations" by selecting "Corporate Overview."    

Investor contacts: 

Media contacts:



William R. LaRue

SVP & Chief Financial Officer

Cadence Pharmaceuticals, Inc.               

Phone: (858) 436-1400  

 

Marites Cristobal Coulter

Media Relations

Edelman

Phone: (323) 202-1424              

Cell: (415) 819-2214

Email: marites.cristobal@edelman.com 

 


'/>"/>
SOURCE Cadence Pharmaceuticals, Inc.
Copyright©2012 PR Newswire.
All rights reserved

Related medicine technology :

1. Upcoming Presentations on Global Market Access Issues and Trends in Health Economics and Outcomes Research at ISPOR 2012 by Novel Health Strategies
2. Ingenuity Systems Named 2013 World Economic Forum Technology Pioneer
3. Brazilian Healthcare Industry Thrives in Favorable Socioeconomic Environment, Finds Frost & Sullivan
4. Frost & Sullivan: Respirator Manufacturers to Develop Innovative Solutions to Overcome Economic Challenges in North America
5. Boston Healthcare Expands Health Economics, Pricing, and Reimbursement Consulting Practice in Asia
6. Philips transforms care to address the economic challenges faced by radiology departments and radiologists worldwide
7. CVS Caremark CEO Addresses Economic Club of Pittsburgh on Reinventing Pharmacy for Better Health
8. Precision Health Economics Adds Executive Sales And Marketing Leader
9. CHPA Statement on PSE Economic Study By AEI Fellow Alex Brill
10. Analysis In Health Economics Review Concludes Effective Medical Obesity Treatment Could Reduce Medicare Spending
11. Organogenesis to Present Large Retrospective Comparative Effectiveness Analysis and Health Economic Data in Chronic Wound Healing at The Symposium on Advanced Wound Care and Wound Healing Society Meeting
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/27/2017)...  West Pharmaceutical Services, Inc. (NYSE: WST ... 2017 and updated financial guidance for the full-year 2017. ... Reported net sales of $397.6 million, ... Net sales at constant currency (organic) grew by 3.9%. ... compared to $0.60 in the prior-year quarter. Second-quarter 2017 ...
(Date:7/26/2017)... Aesthetics, a leading medical aesthetic clinic in Singapore ... skin conditions from the inside. The natural process of ... skin becomes more transparent due to the thinning of the epidermis. Over ... the sun contributes to aging skin, causing age spots and other ... ...
(Date:7/26/2017)... 26, 2017 The Galien Foundation announced ... USA Award Nominees. Counted among the global ... recognizes outstanding biomedical and technology product achievement that improves the ... qualify, each candidate must be U.S. Food and Drug Administration ... demonstrate tremendous potential to impact human health. Sales data are ...
Breaking Medicine Technology:
(Date:7/27/2017)... Plano, TX (PRWEB) , ... July 27, 2017 ... ... technology and outsourced services, announces the internal promotion of Elrene Clinkscales to Vice ... Operations – Claims & Remittance Management, reporting to Derek Morkel, chief executive officer ...
(Date:7/27/2017)... ... 2017 , ... Team Novo Nordisk, the world’s first all-diabetes professional cycling team, ... a stagiaire for the remainder of the 2017 season. One of our best development ... Tour of Utah. , “Every season we are excited to move an athlete from ...
(Date:7/26/2017)... ... July 26, 2017 , ... Written By: Ashley D. Beall, ... in drug therapy for patients living with relapsing and primary multiple sclerosis that ... cell targeted therapy that has been proven to significantly reduce signs of disease ...
(Date:7/26/2017)... ... July 26, 2017 , ... “We are dentists and we thought there ... Jose, Calif., “so we invented the MAGNETIC/ LOCK BRACKETS.” , The patent-pending MAGNETIC/ LOCK ... In doing so, it offers an effective alternative to traditional braces. As a result, ...
(Date:7/26/2017)... ... July 26, 2017 , ... “We are thrilled to be ... for patients to schedule an appointment online in real time,” said Keith English, LocalMed ... Smiles provider directory will bring more Six Month Smiles patients to their providers.” , ...
Breaking Medicine News(10 mins):