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New Data Demonstrating the Impact of Opioid-Related Adverse Events on Total Hospital Cost Presented at American Society of Health-System Pharmacists Meeting
Date:12/5/2011

to urinary retention, pruritus and respiratory depression, some of which, such as respiratory depression, can be severe and life threatening," said Gary Oderda, PharmD, MPH, professor in the Department of Pharmacy Practice and director of the Utah Pharmacotherapy Outcomes Research Center at the University of Utah College of Pharmacy, who will present the poster. "In addition to the negative impact these events have on patients' recovery, these data indicate they place a significant economic burden on hospitals and health care systems, as well."

Dr. Oderda conducted this research in conjunction with TJ Gan, M.D., MHS, professor and vice chair, Department of Anesthesiology at Duke University Medical Center, and in collaboration with Premier Research Services, part of the Premier Healthcare Alliance. The research was supported by Pacira Pharmaceuticals, Inc.

"These data not only demonstrate the strong correlation between total opioid consumption, opioid-related adverse events and cost, but also highlight the value of a multimodal, opioid-sparing approach to postsurgical pain management," said Dr. Gan. "By utilizing a combination of therapeutics, surgeons can provide effective analgesia while limiting the adverse events associated with opioids, which could provide significant benefits to both patients and hospital economics."

A regional health system analysis conducted by Barnabas Health will also be presented at 2 p.m. CST today during a poster session at ASHP. The research was supported by Pacira Pharmaceuticals, Inc. This analysis identified patients undergoing total abdominal hysterectomy (TAH) in one of Barnabas Health's six hospitals from January 2007 to December 2010 in order to identify any relationship between opioid use and increased LOS and overall cost in patients undergoing TAH. 

The 97 TAH patients with the longest LOS, termed "outliers," were matched to a control group of TAH surgical patients in the database. Medical re
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SOURCE Pacira Pharmaceuticals, Inc.
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