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New Data Demonstrate Welchol(R) (colesevelam HCl) Significantly Improved Lipid and Glycemic Measures in Patients With High LDL Cholesterol and Prediabetes
Date:4/23/2010

PARSIPPANY, N.J., April 23 /PRNewswire/ -- Results of a new study showed that Welchol® (colesevelam HCl) 3.75 g/d significantly improved lipid and glycemic measures in patients with high LDL cholesterol and prediabetes (impaired fasting glucose and/or impaired glucose tolerance).  The randomized, placebo-controlled, double-blind study was presented today at the American Association of Clinical Endocrinologists (AACE) 19th Annual Meeting and Clinical Congress in Boston.(1)  These data are consistent with previous studies that have shown Welchol to be safe and effective in lowering A1C, fasting plasma glucose and low-density lipoprotein cholesterol (LDL-C) in adult patients with type 2 diabetes.(2)

"These new findings are important because they provide valuable information on the effects of Welchol to significantly reduce LDL cholesterol, fasting plasma glucose, and A1C levels in patients at high risk for developing type 2 diabetes," said Yehuda Handelsman, MD, FACP, FACE, Medical Director of the Metabolic Institute of America in Tarzana, Calif. and investigator of the study.  "The evaluation of Welchol in this high risk population underscores recent guidelines established by AACE, which recommended physicians target and treat underlying disorders such as high cholesterol and elevated glucose levels in people with prediabetes."(3)

Approximately 57 million adults in the U.S. have impaired fasting glucose and/or impaired glucose tolerance, which puts them at a three to 10 times higher risk of developing type 2 diabetes and a 1.5 times greater risk of cardiovascular disease.(3,4,5)  A recent position statement from the American Diabetes Association (ADA) stated that individuals with an A1C level of
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SOURCE Daiichi Sankyo
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