Navigation Links
New Clinical Data Further Supports Chromium Picolinate's Role in Enhancing Brain Activity in Older Adults
Date:3/4/2008

Study Used Key Ingredient in Core4Life Advanced Memory Formula(TM)

PURCHASE, N.Y., March 4 /PRNewswire-FirstCall/ -- Nutrition 21, Inc. (Nasdaq: NXXI), a developer and marketer of nutritional supplements that help consumers manage blood sugar levels, improve cardiovascular health, enhance memory and address chronic joint pain, today announced the results of a clinical study that showed daily supplementation with 1000 mcg of chromium, as chromium picolinate, increased brain activity in older adults experiencing early memory decline. Researchers from the University of Cincinnati presented the study results at the 19th annual meeting of the American Neuropsychiatric Association.

Blood circulation and nutrient flow to the brain can decrease with aging and affect cognition. A previous study presented in December 2007 showed that using chromium picolinate, which can improve insulin sensitivity and enhance utilization of glucose -- the brain's main fuel -- improved memory function in older adults.

"The current study showed that older adults taking chromium picolinate exhibited greater brain activation while engaged in a cognitively demanding task," said Robert Krikorian, Ph.D., lead investigator and associate professor, Department of Psychiatry, University of Cincinnati College of Medicine. "These brain imaging results support findings from the prior study suggesting that chromium picolinate may be beneficial for older adults with early memory decline and metabolic irregularities, factors that substantially increase the risk for dementia. These findings substantiate the need for continued research to determine the nature and extent of this enhancement."

The randomized, double-blind, placebo-controlled study measured whether supplementation with chromium picolinate for a 12-week period might affect brain activation under working memory task demands in 13 older adults with early memory decline. Functional magnetic resonance imaging (fMRI) scans were performed while study participants worked on a challenging cognitive task that involved holding in mind and manipulating visual information while resisting potential distractions. Results from the fMRI scans showed that subjects receiving chromium picolinate exhibited greater activation in right thalamic, right temporal, right posterior parietal and bilateral frontal regions (p = .005).

At treatment termination, urinary chromium to creatinine ratios were elevated in the chromium picolinate group (p < .0001). There was no significant difference between the groups with respect to age (72 versus 73 years), education (15.8 versus 17.3 years), mood disturbance (11 versus 4.5 Profile of Mood States score), and level of memory impairment (.89 versus .63 Clinical Dementia Rating sum boxes score).

"The earlier memory study conducted by the University of Cincinnati team in addition to the current data using functional MRI supports the ability of chromium picolinate to help improve working memory in the elderly," said James Komorowski, M.S., Vice President of Scientific Affairs at Nutrition 21. "Since chromium picolinate is one of three core components of our Core4Life Advanced Memory Formula product, we're pleased to see that ongoing research evaluating its effect on cognitive function is showing consistent beneficial results."

Study investigators used Nutrition 21's proprietary chromium picolinate found in Core4Life Advanced Memory Formula(TM), a nutritional supplement specifically formulated to improve brain health. Core4Life Advanced Memory Formula, available in soft gel form, contains chromium picolinate, phosphatidylserine (PS) and DHA. These ingredients have been scientifically tested for their ability to improve cognitive function:
-- Chromium picolinate is an essential trace mineral that promotes healthy

blood sugar levels, which is important because glucose helps fuel the

brain.

-- PS is a naturally occurring phospholipid nutrient essential to the

functioning of all cells of the body, but is most concentrated in the

brain. PS supports communication between brain cells and promotes

improved memory.

-- DHA is an omega-3 fatty acid, most commonly found in fish oil, which

maintains brain fluidity and may help in the maintenance of cognitive

function.

Core4Life Advanced Memory Formula is manufactured according to strict Food and Drug Administration (FDA) guidelines. This product can be taken safely alone or with medication, with optimal results seen in 30 to 90 days. Core4Life Advanced Memory Formula is available at major retailers nationwide in the vitamin section. For more information visit http://www.core4life-amf.com.

About Nutrition 21

Nutrition 21, Inc. (Nasdaq: NXXI), headquartered in Purchase, NY, is a nutritional bioscience company and the maker of chromium picolinate-based and omega-3 fish oil-based supplements with health benefits substantiated by clinical research. Nutrition 21 holds more than 30 patents for nutrition products and uses. Nutrition 21's portfolio of health and wellness brands include: Chromax(R), Core4Life Advanced Memory Formula(TM), Diabetes Essentials(TM), Iceland Health(R) Maximum Strength Omega-3 and Iceland Health(R) Joint Relief. The company also manufactures private label supplements and ingredients for third parties. Nutrition 21 distributes its products nationally through more than 29,000 major food, drug and super center retailers as well as internationally. For more information please visit http://www.nutrition21.com.

CONTACT: Maryrose Lombardo, 914-701-4525


'/>"/>
SOURCE Nutrition 21, Inc.
Copyright©2008 PR Newswire.
All rights reserved

Related medicine technology :

1. Dendreon Announces Publication of Phase 1 Study Highlighting Immunologic and Clinical Activity of Lapuleucel-T (Neuvenge(R)) in Advanced Breast Cancer Patients
2. EDAP Announces Launch of Clinical Study Combining HIFU and Chemotherapy for Localized Aggressive High Risk Prostate Cancer
3. EpiCept Reports Expansion of Clinical Development For Licensed Cancer Compound
4. Auxilium Pharmaceuticals, Inc. Receives Clearance to Resume Clinical Trials for XIAFLEX(TM)
5. Romark Initiates Clinical Trial of Alinia(R) for Chronic Hepatitis C in the United States
6. The Multiple Myeloma Research Consortium (MMRC) and Proteolix Initiate Phase 2 Clinical Trial Investigating Carfilzomib for the Treatment of Multiple Myeloma
7. Millennium Initiates Clinical Trial to EVOLVE the Treatment of Patients with Newly Diagnosed Multiple Myeloma
8. Potential Safety Issue Identified in Ongoing Phase 2 Clinical Study of HCV-796
9. Clinical Trial Effectiveness: How Pharmas & Biotechs Save Cost with Savvy Investigator Management
10. Callisto Pharmaceuticals Opens Additional Sites for Phase II Clinical Trial of Atiprimod in Advanced Carcinoid Cancer Patients
11. Phosphagenics Announces Positive Phase 1b Transdermal Insulin Clinical Trial Results
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/23/2016)... 2016 Research and Markets has announced ... report to their offering. ... a favourable commercial environment for MedImmune to enter. The US ... will serve to drive considerable growth for effective anti-influenza medications. ... cap sales considerably, but development is still in its infancy. ...
(Date:6/23/2016)... 23, 2016  Astellas today announced the establishment of Astellas Farma Colombia (AFC), a new affiliate with operations headquartered ... Latin America . ... ... ... ...
(Date:6/23/2016)... -- Research and Markets has announced the ... (United States, China, Japan, Brazil, United Kingdom, Germany, France, ... Surgical Procedure Volumes: ... provides surgical procedure volume data in a geographic context. ... analysis of growth drivers and inhibitors, including world population ...
Breaking Medicine Technology:
(Date:6/26/2016)... ... 2016 , ... Quality metrics are proliferating in cancer care, and are derived ... eye of the beholder, according to experts who offered insights and commentary in the ... Care. For the full issue, click here . , For the American Society ...
(Date:6/26/2016)... , ... June 26, 2016 , ... Pixel Film Studios ... X. , "Film editors can give their videos a whole new perspective by using ... - CEO of Pixel Film Studios. , ProSlice Levels contains over 30 Different ...
(Date:6/26/2016)... ... 2016 , ... Brent Kasmer, a legally blind and certified personal trainer is helping to develop ... The fitness app plans to fix the two major problems leading the fitness industry today:, ... all type program , They don’t eliminate all the reasons people quit their ...
(Date:6/25/2016)... (PRWEB) , ... June 25, 2016 , ... ... health policy issues and applications at AcademyHealth’s Annual Research Meeting June 26-28, 2016, ... work on several important health care topics including advance care planning, healthcare costs ...
(Date:6/25/2016)... ... June 25, 2016 , ... The temporary closing of Bruton Memorial Library on June ... , brings up a new, often overlooked aspect of head lice: the parasite’s ability to ... is not a common occurrence, but a necessary one in the event that lice have ...
Breaking Medicine News(10 mins):