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New Approach to Celiac Testing Identifies More Patients at Risk
Date:8/27/2013

stine and can lead to significant medical complications such as autoimmune disease, infertility, liver failure and cancer. Celiac disease usually develops in childhood and is life-long, but early diagnosis and treatment can reduce the risk of adverse health complications.

Conservative estimates using an older antibody test had previously suggested the number of Australians with celiac disease as no more than one in 100. Findings in this study now suggest that the prevalence of celiac disease in the U.S. population, which is estimated to be one in 133 on the basis of antibody testing alone, may need to be re-evaluated.

Dr. Tye-Din in collaboration with Dr. Bob Anderson, chief scientific officer at ImmusanT, worked with Barwon Health, Deakin University, Healthscope Pathology and the University of Queensland Diamantina Institute to develop and trial the new diagnostic approach.

"Accurate and timely diagnosis of celiac disease is important for the health of patients who are managing the disease. Making a diagnosis based on a blood test alone or starting a gluten-free diet without a confirmatory test is insufficient and can impose an unnecessary and very restrictive exclusion diet for the rest of a person's life," said Dr. Anderson. "Given the life-long impact of a diagnosis of celiac disease, ensuring a definitive diagnosis is crucial. This study provides a strategy to improve the diagnosis of celiac disease in the community by combining the benefits of antibody and genetic testing before proceeding to biopsy."

The research was supported by INOVA Diagnostics Inc; ImmusanT, which acquired the assets of Nexpep Pty. Ltd; the National Health and Medical Research Council; the Victorian Health Promotion Foundation; the Geelong Region Medical Research Foundation; and the Victorian government.

ImmusanT Contact:
Leslie J. Williams, President & CEO
(617) 299-8399, ext. 201'/>"/>

SOURCE ImmusanT Inc.
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