Navigation Links
New Analysis of Data Presented at AHA Regarding Effect of Effient® (Prasugrel) on Cardiovascular Events in STEMI Patients According to Timing of PCI
Date:11/16/2011

ORLANDO, Fla., Nov. 16, 2011 /PRNewswire/ -- An analysis of the TRITON-TIMI 38 trial presented today in an oral session at the American Heart Association (AHA) Scientific Sessions meeting examined the effect of Effient® (prasugrel) on cardiovascular (CV) events (CV death, myocardial infarction [MI] and stroke) compared to clopidogrel relative to the timing of percutaneous coronary intervention (PCI) in acute coronary syndrome (ACS) patients with ST-segment elevation myocardial infarction (STEMI).(1)

At 15 months, primary PCI patients with STEMI had an 11 percent relative risk reduction in CV events, and secondary PCI patients had a 35 percent relative risk reduction with Effient compared to clopidogrel (HR 0.89, 95% CI 0.69-1.13; and HR 0.65, 95% CI 0.46-0.93, respectively).  Absolute risk reduction for Effient compared to clopidogrel was 1.3 percent for the primary PCI group and 4.6 percent for the secondary PCI group.(1)

"Not all ST-elevation MI patients are treated with primary PCI; therefore, understanding the effects of more potent inhibition of platelets in ACS patients who are treated with primary PCI or those treated with delayed PCI is important for choosing antiplatelet therapies," said lead author Jacob A. Udell, MD, MPH, Clinical Fellow, Cardiovascular Medicine, Brigham & Women's Hospital. "These data demonstrate that efficacy and bleeding rates for Effient are consistent with the overall TRITON-TIMI 38 trial results irrespective of when STEMI patients undergo intended PCI."

In the study, primary PCI was defined as PCI within 12 hours from onset of acute coronary syndrome (ACS) symptoms and secondary PCI was defined as PCI more than 12 hours after initial onset or initial medical therapy. Of the 3,534 STEMI patients from the TRITON-TIMI 38 trial who were included in this analysis, 2,340 (68 percent) underwent primary PCI and 1,085 underwent secondary PCI. Randomization to Effient or clopidogrel occurred at presentati
'/>"/>

SOURCE Eli Lilly and Company
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8

Related medicine technology :

1. Triple Analysis: Leukemia, Cancer Vaccines and Peptides
2. Triple Analysis: Prostate Cancer, Angiogenesis and Peptides
3. PRA Early Phase Experts to Speak at Bioanalysis Conference
4. Implantable Cardioverter Defibrillators and Cardiac Resynchronization Therapy-Defibrillators - Global Pipeline Analysis, Competitive Landscape and Market Forecasts to 2017
5. New RAPID 1 Post-Hoc Analysis Showed Early Response to Cimzia® (certolizumab pegol) at Week 12 was Predictive of Week 52 Response
6. Turkey Ophthalmic Devices Investment Opportunities, Analysis and Forecasts to 2017
7. ReportsnReports - Hyper Acute Pancreas (Pancreatic Cancer) - Analysis and Forecasts to 2020
8. Molecular Devices, LLC Introduces SoftMax Pro® 6 Microplate Data Acquisition and Analysis Software With Powerful New Data Analysis and Reporting Features
9. Gastric Cancer - Global Drug Forecasts and Treatment Analysis to 2020 - Volume I 2011
10. DIFICID™ Demonstrated Early Superiority in the First 12 Days Compared to Vancomycin in New Analysis of Phase 3 Study Results
11. Afinitor (Breast Cancer) - Analysis and Forecasts to 2020
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/15/2014)... 2014 Shire plc (LSE: SHP, NASDAQ: ... Trading (OFT) approval condition to the announced tender offer for all ... As a result of the waiver, the transaction is no ... tender offer on January 24, 2014 following the currently scheduled expiration ...
(Date:1/15/2014)...  In an unprecedented effort to curb the spread of "superbugs" such ... vehicles, an advanced and portable UV germicidal lamp manufactured by MRSA-UV ... In order to prevent EMS paramedics and transport ... West Palm Beach Fire Rescue is the first in ...
(Date:1/15/2014)... , Jan. 15, 2014 The Cadence Fitness & ... Center by the Medical Fitness Association, a non-profit organization ... their full potential. The Cadence Fitness & Health Center ... suburbs and second in the Chicagoland area. ...
Breaking Medicine Technology:Shire Waives OFT Condition Relating to the Acquisition of ViroPharma Inc. 2Shire Waives OFT Condition Relating to the Acquisition of ViroPharma Inc. 3Superbugs No Longer Ride In Rescue Vehicles 2Cadence Fitness & Health Center Certified as Medical Fitness Facility 2Cadence Fitness & Health Center Certified as Medical Fitness Facility 3
... Deep Vein, Thrombosis; $10 Million National Institutes ... Device Technique Can Prevent Post-Thrombotic Syndrome, FAIRFAX, Va., ... of a catheter-based treatment for deep vein thrombosis,-- will ... clot,removal devices to prevent post-thrombotic syndrome in patients with ...
... controlled study finds significant healing and anti-infective ... hope for patients and caregivers, PRINCETON, N.J., Sept. ... today that its key product,MEDIHONEY(TM) Wound & Burn Dressing ... randomized controlled clinical trial to significantly,improve the healing rates ...
Cached Medicine Technology:Pivotal National Trial Uses Newest Interventional Radiology Treatment to Bust Blood Clots in Legs 2Pivotal National Trial Uses Newest Interventional Radiology Treatment to Bust Blood Clots in Legs 3Pivotal National Trial Uses Newest Interventional Radiology Treatment to Bust Blood Clots in Legs 4Derma Sciences' MEDIHONEY(TM) Proven to Speed Healing in Stalled Leg Ulcers 2Derma Sciences' MEDIHONEY(TM) Proven to Speed Healing in Stalled Leg Ulcers 3
(Date:7/9/2014)... Using an innovative tool that captures heretofore hidden ways ... identified a protein that makes breast cancer cells more ... to trigger cancer,s spread in part by blocking two ... finding that suggests these two disease processes could have ... the July 10 issue of Nature , points ...
(Date:7/9/2014)... findings from Fox Chase Cancer Center paint a relatively ... of breast cancers that have spread to the chest ... that grow into the skin, regardless of size and ... as stage III and called "locally advanced" tumors, ... cancer, often with poor survival. Locally advanced breast cancers ...
(Date:7/9/2014)... -- Researchers from The Miriam Hospital have found ... who are also depressed have difficulty sticking to ... particularly true for women, and screening and brief ... of treatment. The study and its findings are ... , Chronic obstructive pulmonary disease is a ...
(Date:7/9/2014)... July 9, 2014 There has been a sharp ... Southwestern Medical Center using MyChart, the online, interactive service ... communicate with their healthcare providers, schedule appointments, and renew ... patients actively using MyChart each year increased ... increased more than 10-fold, according to a study by ...
(Date:7/9/2014)... Cup highlights, Brian Williams refreshing old school rap classics, ... railings. A University of Colorado Cancer Center study published ... YouTube also allows researchers, journals, and health advocates to ... cancer and prevention. , "No matter what field you,re ... communicate around the world," says Chante Karimkhani, MD candidate ...
Breaking Medicine News(10 mins):Health News:Protein pushes breast cancer cells to metastasize 2Health News:Protein pushes breast cancer cells to metastasize 3Health News:Fox Chase researchers recommend updating the staging criteria for breast cancer diagnoses 2Health News:Fox Chase researchers recommend updating the staging criteria for breast cancer diagnoses 3Health News:Miriam Hospital study examines effect of depressed mood on pulmonary rehab completion 2Health News:MyChart use skyrocketing among cancer patients, UT Southwestern study finds 2Health News:MyChart use skyrocketing among cancer patients, UT Southwestern study finds 3Health News:Study of dermatology on YouTube shows new ways science reaches public 2
... Sacramento - On Tuesday, April 28, at 1:30 p.m., Donate, ... Padilla,s legislation Senate Bill 552 requiring ... classes to include 15 minutes of education regarding, ... would provide California students with the basic knowledge ...
... A defining hallmark of Alzheimer,s disease is the accumulation ... "senile plaques," in the brain,s cortex and hippocampus, where ... California, San Diego School of Medicine have identified a ... increase in the generation of Aβ. Their findings, ...
... 2009 GuidanceBETHESDA, Md., April 27 Hanger Orthopedic Group, Inc. ... million for the quarter ended March 31, 2009, an increase ... prior year. Net income increased $0.9 million, or 26.6%, ... $3.6 million last year. Net income applicable to common ...
... Health Association (APHA) urges the public to use the current ... and their families are prepared for potential pandemics, disasters or ... too early to know the degree to which the current ... the speed with which the virus has spread around the ...
... Preparedness Manual," a complimentary resource that can assist in planning for, ... ... Houston, TX (PRWEB) April 27, 2009 -- With more than ... the recent swine influenza outbreak has triggered global concern as governments ...
... computers, pharmacists for proper prescribing , , MONDAY, April 27 ... cost lives and dollars each year in the United ... pharmacists can work to reduce these mistakes. , Medication ... affecting at least 1.5 million people every year and ...
Cached Medicine News:Health News:Donate Life California to Hold Press Conference on Organ Donation Education, April 28, 1:30 p.m., on State Capitol West Steps 2Health News:Novel role of protein in generating amyloid-beta peptide 2Health News:Hanger Orthopedic Group, Inc. Reports $0.14 EPS on 26.6% Increase in Net Income for the First Quarter 2009 2Health News:Hanger Orthopedic Group, Inc. Reports $0.14 EPS on 26.6% Increase in Net Income for the First Quarter 2009 3Health News:Hanger Orthopedic Group, Inc. Reports $0.14 EPS on 26.6% Increase in Net Income for the First Quarter 2009 4Health News:Hanger Orthopedic Group, Inc. Reports $0.14 EPS on 26.6% Increase in Net Income for the First Quarter 2009 5Health News:Hanger Orthopedic Group, Inc. Reports $0.14 EPS on 26.6% Increase in Net Income for the First Quarter 2009 6Health News:Swine Flu Reinforces the Importance of Preparing for Emergencies, Says APHA 2Health News:'Pandemic Preparedness Manual' Offers Guide to Dealing with Possible Swine Flu Pandemic 2Health News:'Pandemic Preparedness Manual' Offers Guide to Dealing with Possible Swine Flu Pandemic 3Health News:Medication Errors Could Be Cut: Experts 2Health News:Medication Errors Could Be Cut: Experts 3Health News:Medication Errors Could Be Cut: Experts 4
Ethicon, medium clip size, 10mm, rotatable take apart...
Solid phase capture sandwich ELISA assay using a microwell format....
The C-Reactive Protein (CRP) assay is used for the quantitative analysis of C-reactive protein in human serum and plasma. Kit is for use with the Abbot Laboratories Aeroset, ARCHITECT c8000 or ARCHI...
... broad menu clinical chemistry analyzer designed for ... Care givers can now perform routine multi-chemistry ... minute of hands-on time. Complete panel results ... expensive laboratory analyzers are available in under ...
Medicine Products: