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New Analysis Shows Potential Cost Savings of Adding Antiepileptic Drug Vimpat® C-V
Date:5/31/2011

according to a variety of measures including physical mobility, ability to carry out activities of daily living, absence of pain and discomfort, and absence of anxiety and depression. In standard practice, if a therapy has shown a QALY under $50,000 per year, it is considered to have met the standard of willingness-to-pay.

About Vimpat®

Vimpat® was approved by the Food and Drug Administration in 2008 as an adjunctive therapy for the treatment of partial-onset seizures in patients with epilepsy 17 years and older. Vimpat® became available in the U.S. in May 2009 as tablet and intravenous formulations. In 2010, Vimpat® was approved as an oral solution.

Vimpat® (film-coated tablets, syrup and solution for infusion) was launched in the European Union in September 2008, as adjunctive therapy for the treatment of partial-onset seizures with or without secondary generalization in patients with epilepsy, aged 16 years and older. Vimpat® solution for infusion may be used when oral administration is temporarily not feasible.

Important safety information about Vimpat® in the U.S.

Warnings and Precautions

AEDs increase the risk of suicidal behavior and ideation. Patients taking Vimpat® should be monitored for the emergence or worsening of depression, suicidal thoughts or behavior, and/or any unusual changes in mood or behavior.

Patients should be advised that Vimpat® may cause dizziness, ataxia, and syncope. Caution is advised for patients with known cardiac conduction problems, who are taking drugs known to induce PR interval prolongation, or with severe cardiac disease. In patients with seizure disorders, Vimpat® should be gradually withdrawn to minimize the potential of increased seizure frequency. Multi-organ hypersensitivity reactions have been reported with antiepileptic dr
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