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New Analysis Shows Potential Cost Savings of Adding Antiepileptic Drug Vimpat® C-V
Date:5/31/2011

ional support for lacosamide's utility as an antiepileptic drug in the reimbursement community, and among healthcare professionals and patients."

"This analysis shows the potential for cost savings when adding lacosamide to a treatment plan and, when combined with more than five years of efficacy and safety data and more than 100,000 patient exposures worldwide, further underscores lacosamide's role in the treatment of epilepsy," added Kathleen Bos, MD, Vice President, U.S. Medical Affairs, UCB, Inc.

Study Details

This analysis is based on published data from two pivotal, multi-national, clinical trials that have yielded more than five years of safety and efficacy data supporting long-term use of lacosamide.  The model simulated the treatment pathway of a hypothetical cohort of 1,000 patients over two years from the third party payer perspective in the United States in 2010. Standard cost- and utility-effectiveness ratios were calculated based on two years of therapy compared with five other standard therapies: carbamazepine, lamotrigine, levetiracetam, topiramate, and valproate.  Separate arms of the cohort compared lacosamide used as an add-on therapy with standard therapies versus those therapies used without lacosamide.  

About Cost-Effectiveness Analysis

Cost-effectiveness analyses calculate the dollar value of changes in health status based on the use of a particular therapy versus standard cost of care. They are increasingly used to determine the relative value of therapies by public and private insurers for reimbursement decisions and in the development of clinical practice guidelines. Additionally, the more subjective health benefits resulting from a therapy, known as utility-value, are commonly determined through QALY calculations.  QALY calculations calculate a dollar amount for each additional year of life added by a therapy and a value for the quality of that life. Quality is defined
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SOURCE UCB
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