Navigation Links
New Analysis Shows Efficacy of REMICADE(R) in Treatment of Ulcerative Colitis in Patients with Recent Disease Onset or Long-Standing Disease
Date:5/20/2008

A Separate Retrospective Analysis of US Employer Claims Suggests a Benefit of Anti-Tumor Necrosis Factor Therapies on Absenteeism Among Employees with

Inflammatory Bowel Disease

SAN DIEGO, May 20 /PRNewswire/ -- Data from a new analysis of the Active Ulcerative Colitis Trials (ACT 1 and ACT 2) showed that at week 8, more than 60 percent of patients with moderately to severely active ulcerative colitis (UC) receiving REMICADE(R) (infliximab) achieved clinical response regardless of disease duration (less than three years versus at least three years). Investigators also reported that at week 30, significant improvements were maintained with nearly half of REMICADE-treated patients having a clinical response. Significant improvements in disease remission and mucosal healing were also reported at weeks 8 and 30 among patients receiving REMICADE and meeting the disease duration criteria. These findings were presented today at the annual Digestive Disease Week(R) (DDW) meeting.

"These data are encouraging because we see that REMICADE is an effective treatment option for patients with active ulcerative colitis, whether recently diagnosed or struggling with the condition for many years," said Dr. Bruce Sands, Associate Professor of Medicine at Harvard Medical School, and study investigator. "Regardless of disease duration, patients receiving REMICADE showed significant improvements in clinical response, remission and mucosal healing, all goals of therapy in the treatment of ulcerative colitis."

In the analysis of 728 patients from ACT 1 and ACT 2, 254 patients had UC for less than three years and 474 patients had UC for at least three years. Clinical response, clinical remission and mucosal healing rates at week 8 for the combined REMICADE treatment group (5 mg/kg and 10 mg/kg) were all significantly higher than the placebo group (P < 0.01) regardless of disease duration; clinical response: 62 percent versus 33 percent for
'/>"/>

SOURCE Centocor
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8

Related medicine technology :

1. Trubion Announces Preliminary Analysis of Phase IIb Results With TRU-015 in Rheumatoid Arthritis
2. Oncology Drugs Development Update - Worldwide Markets and Forecasts of Approved EGFr/HEr2 Inhibitors, Treatment Costs, Pathway Analysis, Current and Expanded Clinical Indications, and Novel Agents in Development
3. New Data From Large Safety Analysis of MYCAMINE Shows Favorable Clinical Safety Profile
4. Immtech Announces Interim Analysis in Phase III African Sleeping Sickness Trial
5. Analysis Shows Vernakalant Hydrochloride Injection Increases Conversion to Normal Heart Rhythm in Acute Atrial Fibrillation Patients Treated Within 48 Hours of Onset
6. New Analysis of Study Data Shows That Asacol(R) (Mesalamine) Delivers Rapid Symptom Relief for Ulcerative Colitis Patients
7. A Sociolinguistic Analysis of In-Office Dialogue Reveals Psychiatrists and Parents Have Significantly Different Perceptions on ADHD and Psychiatric Comorbidities
8. Favrille Provides Update on Timing of Analysis from Pivotal Phase 3 Clinical Trial; Reports Third Quarter 2007 Financial Results
9. Results Of VYVANSE(TM) (lisdexamfetamine dimesylate) Effect Size Analysis Presented at Major Scientific Meeting
10. Progen Presents Additional Analysis of Data from PI-88 Phase 2 Liver Cancer Study at American Association for the Study of Liver Diseases
11. Retrospective Analysis Finds That Initiation of Insulin Glargine in Patients With Type 2 Diabetes was Associated With a Lower Incidence Rate of Myocardial Infarction as Compared With NPH Insulin
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/10/2014)... BURLINGTON, Mass. , July 10, 2014 /PRNewswire/ ... three-quarters of surveyed infectious disease (ID) specialists are ... Medicines Company,s Orbactiv (oritavancin) for use as OPAT, ... to prescribe these agents to their hospital inpatients. ... percent) of OPAT patients are initiated on OPAT ...
(Date:1/15/2014)... Jan. 15, 2014 /PRNewswire-iReach/ -- ChinaMarketResearchReports.com adds "China Orthopedic ... . (Photo: http://photos.prnewswire.com/prnh/20140115/MN46792 ) ... policy support, China,s orthopedic instrument ... total market size rising from 3.28 billion yuan in ...
(Date:1/15/2014)... the leading health care supply chain expertise, analytics and ... national contracts that expand its portfolio to provide hospital ... These include manufacturer product and service agreements, as well ... IT consulting support. New Novation agreements ...
Breaking Medicine Technology:Long-Acting Antibiotics Offering Once-Weekly Dosing Will See Favorable Uptake and Use as Outpatient Parenteral Antimicrobial Therapy (OPAT) 2Long-Acting Antibiotics Offering Once-Weekly Dosing Will See Favorable Uptake and Use as Outpatient Parenteral Antimicrobial Therapy (OPAT) 3Orthopedic Instrument Industry in China Markets Forecast to 2015 2Orthopedic Instrument Industry in China Markets Forecast to 2015 3New Novation Information Technology VAR Contracts Offer Significant Savings to Hospitals 2
... Hologic, Inc. (Hologic or the Company) (Nasdaq: HOLX ... diagnostics, medical imaging systems and surgical products dedicated to ... opening of its new Asia Pacific regional offices and ... in Hong Kong. Sales, product support, training, R&D, ...
... may signal a positive sign for the economy , ... Institute(R) ( www.ecri.org ), an independent nonprofit ... and offers procurement support to more than 2,000 U.S. ... members for medical technology acquisition support, a strong signal ...
Cached Medicine Technology:Hologic Expands Healthcare Investment in Asia 2Hologic Expands Healthcare Investment in Asia 3ECRI Institute Sees Upward Trend in Hospital Medical Technology Evaluation Activity 2
(Date:7/12/2014)... "The second toes cross over the big toes on my ... an inventor from East Hartford, Conn. This gave him idea ... He then created a prototype of the Comfort Sock, which ... toes from overlapping. This avoids discomfort and pain, which allows ... use, it's ideal for people with foot problems, athletes and ...
(Date:7/12/2014)... York, New York (PRWEB) July 12, 2014 ... continue to move forward in U.S. courts, Bernstein Liebhard ... ties elevated metal ion levels to the failure of ... July 2nd issue of The Journal of Bone & ... had received unilateral Articular Surface Replacement prostheses at least ...
(Date:7/12/2014)... NY (PRWEB) July 12, 2014 ... 2020 - New and Late-Stage Four-Factor PCCs and ... analysis of the critical care market in the ... Canada. The report provides an estimation of market ... 2020. It covers critical care indications that are ...
(Date:7/12/2014)... Arab Emirates (PRWEB) July 12, 2014 ... Los Angeles basketball legend is heading to the UAE. ... and six-time champion will be in the UAE from ... Fitness Weekend in support of diabetes awareness. The event ... award-winning entertainment marketing and event management company based in ...
(Date:7/12/2014)... Restore My Vision Today is a ... a couple boasting very impressive credentials on the field ... Today as a way to help consumers do without ... their respective patients’ treatments . , In ... trove of pertinent information relevant to eye care like:, ...
Breaking Medicine News(10 mins):Health News:DePuy Pinnacle Hip Lawsuit News: Bernstein Liebhard LLP Notes Release of New Study Tying Elevated Metal Ions to Metal-on-Metal Hip Failure 2Health News:DePuy Pinnacle Hip Lawsuit News: Bernstein Liebhard LLP Notes Release of New Study Tying Elevated Metal Ions to Metal-on-Metal Hip Failure 3Health News:DePuy Pinnacle Hip Lawsuit News: Bernstein Liebhard LLP Notes Release of New Study Tying Elevated Metal Ions to Metal-on-Metal Hip Failure 4Health News:Critical Care Therapeutics in Major Developed Market is Expected to Grow at a CAGR of 4.7% to $2.5 Billion in 2019 2Health News:Critical Care Therapeutics in Major Developed Market is Expected to Grow at a CAGR of 4.7% to $2.5 Billion in 2019 3Health News:Critical Care Therapeutics in Major Developed Market is Expected to Grow at a CAGR of 4.7% to $2.5 Billion in 2019 4Health News:Critical Care Therapeutics in Major Developed Market is Expected to Grow at a CAGR of 4.7% to $2.5 Billion in 2019 5Health News:Critical Care Therapeutics in Major Developed Market is Expected to Grow at a CAGR of 4.7% to $2.5 Billion in 2019 6Health News:Los Angeles Basketball Legend Headed to Dubai 2Health News:Los Angeles Basketball Legend Headed to Dubai 3Health News:Restore My Vision Today | Groundbreaking Book Reveals How To Restore Your Vision Without The Use of Glasses – Vinamy 2Health News:Restore My Vision Today | Groundbreaking Book Reveals How To Restore Your Vision Without The Use of Glasses – Vinamy 3
... Omega-3 polyunsaturated fatty acids it has been revealed that ... benefits. // ,They influence mood, personality and behavior ... by University of Pittsburgh School of Medicine researchers at ... Society in Denver. ,The study comprised 106 ...
... who died on Saturday suspected to be of bird flu ... high alert.// ,The 32-year-old man is believed ... a busy city in China's Guangdong province, bordering Hong Kong. ... and died within nine days of hospitalisation. ,Many ...
... Justice Cyriac Joseph has expressed the need for quality ... must not leave any stone unturned to weed out ... Justice, this is a matter of grave concern to ... education. The educationists, professionals, governments and all the stakeholders ...
... University Medical Center researchers have discovered that distinct regions ... faced with ambiguous choices versus// choices involving only risk. ... risky choices, and how such risk-taking can become an ... were published in the journal Neuron. ,The ...
... and sound health info Kerala and Goa have lifted the ... revealed by Minister for Medical Education and Animal Husbandry V.S. ... that this indicates that the situation is under control. ... make policies Chief Minister H.D. Kumaraswamy said the Government has ...
... decided to test the effects of radiation released from of ... human skin in order to determine if these transmissions are ... is scheduled to begin sometime next week will expose a ... phone radiation for about 60 minutes or the duration of ...
Cached Medicine News:Health News:Distinct Brain Sections Are Activated While Making Risky Decisions 2
... slot into the side ... monitor, so patient information ... patient's side. Data is ... and storage at the ...
... Telemetry System is a telemetry system ... which require monitoring and performance. With ... able to monitor patients from virtually ... and wireless bedsides. Now, monitoring your ...
TeleRehab Advantage is a monitoring system that automates the generation of outcomes data. Patient information and session information is automatically transferred from the monitoring program to Outc...
... Clearly, the ISI Lexan Universal ... surgical table for lower and ... head and neck, and lower ... traction package gives you the ...
Medicine Products: