Navigation Links
New Analysis Shows Age has a Significant Effect on Outcomes in Patients Being Treated for Clostridium difficile Infection (CDI)
Date:2/14/2013

JERSEY CITY, N.J., Feb. 14, 2013 /PRNewswire/ -- Optimer Pharmaceuticals, Inc. (Nasdaq: OPTR) today announced that the February 2013 Journal of the American Geriatrics Society published results from a multivariate analysis demonstrating that advancing age is a predictor of deterioration in treatment outcomes in patients with Clostridium difficile infection (CDI). The analysis was performed using data from two large, randomized Phase 3 clinical studies that compared the efficacy of DIFICID® (fidaxomicin) tablets to vancomycin for the treatment of CDI. The new analysis predicts that with each decade increase after the age of 40, rates of clinical cure and sustained clinical response decrease by 17% and 13% with treatment, respectively, per decade (OR=0.83, 95% CI [0.72, 0.95], p=0.008; and OR=0.87, 95% CI [0.79, 0.94], p<0.001), while rates of disease recurrence increase by 17% (OR=1.17, 95% CI [1.04, 1.30], p=0.007). 

(Logo:  http://photos.prnewswire.com/prnh/20090413/LA97352LOGO)

Results of the analysis showed that DIFICID and vancomycin were comparably effective in attaining clinical cure in all age groups studied; in those younger than 40 years of age, clinical cure was achieved in 97.2% of patients and in those older than 80, clinical cure was achieved in 87.5% to 88.2% of patients. For patients who achieved clinical cure, DIFICID-treated patients were half as likely to have had a recurrence compared to patients treated with vancomycin (OR=0.46, 95% CI [0.32, 0.67], p<0.001). The analysis showed the probability of sustained clinical response nearly doubled among DIFICID-treated patients compared to patients who received vancomycin (OR=1.86, 95% CI [1.40, 2.47], p<0.001). When researchers conducted an analysis adjusting for age a
'/>"/>

SOURCE Optimer Pharmaceuticals, Inc.
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related medicine technology :

1. Ventana Receives FDA Clearance for p53 (DO-7) Image Analysis and Digital Read Applications
2. Global Ablation Technologies Market (2011-2016) - By Application and Devices in Radiofrequency, Cryoablation, Microwave, Ultrasound, Hydrothermal, Radiation, Electrical, Light/Laser and Hydromechanical - Global Trends & Competitive Analysis
3. Osteoporosis Drug Market- Global And China Market Analysis, Size, Trends And Forecast (2010-2015)
4. Large-Scale Meta-Analysis Shows Age Not a Social Barrier to Opioid Use and Misuse
5. Purdue Pharma L.P. To Present Analysis Of Butrans® (buprenorphine) Transdermal System CIII Clinical Data At American Pain Society Annual Meeting
6. Negative Pressure Wound Therapy (NPWT) - Global Pipeline Analysis, Competitive Landscape and Market Forecasts to 2018
7. Demand for Product Pipeline Review and Analysis Rises in the Global Pharma Industry
8. Lifeline Biotechnologies, Inc. Receives Patent Award, a Device for Breast Tissue Temperature Analysis for Determining Cancer Conditions
9. Ovarian Cancer Therapeutics - Global Drug Forecasts and Treatment Analysis 2020
10. Clinical Chemistry Market Report & Forecast (2012 - 2015): Global Analysis
11. Medical Diagnostic & Therapeutic Ultrasound Devices Market (2012 - 2017) - Global Trends & Competitive Analysis
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/30/2014)... YORK , Oct. 30, 2014  The number ... States is growing steadily, thanks to drug ... as a result of the economic downturn, retail clinic ... a year of opportunities, as the number of retail ... researcher,s report, Retail Clinics Market Overview and 2014 ...
(Date:10/30/2014)... Oct. 30, 2014 Molecular Profiles Ltd., a ... ) and Maryland -based Xceleron have ... efficiency during clinical development that will be launched at ... week. This partnership extends Molecular Profiles, new ... launched earlier this month. The company also has complementary ...
(Date:10/30/2014)... Oct. 30, 2014  CytRx Corporation (NASDAQ: ... company specializing in oncology, today announced an upcoming ... drug candidate, aldoxorubicin.  The presentation, titled, "Drug Conjugates ... be given by Sant P. Chawla , ... and principal investigator of the Company,s ongoing global, ...
Breaking Medicine Technology:Report: Drugstore Chains Drive Retail Clinic Growth 2Report: Drugstore Chains Drive Retail Clinic Growth 3Molecular Profiles To Launch US Strategic Alliance At AAPS 2Molecular Profiles To Launch US Strategic Alliance At AAPS 3CytRx Announces Oral Presentation at 2014 Chemotherapy Foundation Symposium 2CytRx Announces Oral Presentation at 2014 Chemotherapy Foundation Symposium 3CytRx Announces Oral Presentation at 2014 Chemotherapy Foundation Symposium 4
... April 26 Isis Pharmaceuticals, Inc. (Nasdaq: ISIS ) announced ... calls focused on the drugs in Isis, development pipeline.  The second call of ... Wednesday, April 28, 2010 at 12:00 p.m. ET .  This ... , , ...
... , TITUSVILLE, N.J. , April 26 The Court ... Pediatrics, a division of Ortho-McNeil-Janssen Pharmaceuticals, Inc., to overturn a 2009 decision ... for CONCERTA (methylphenidate HCl) Extended-Release Tablets CII is invalid and not infringed ... , In ...
Cached Medicine Technology:Isis Pharmaceuticals to Discuss Its Metabolic Franchise in a Conference Call on Wednesday, April 28 2Isis Pharmaceuticals to Discuss Its Metabolic Franchise in a Conference Call on Wednesday, April 28 3CONCERTA(R) Patent Appeal Denied 2CONCERTA(R) Patent Appeal Denied 3
(Date:10/30/2014)... October 30, 2014 Paramount Rx, a ... is increasing efforts to help people save money through ... to increase for prescription drugs in the new health ... and resources to bridge the relationship between consumers, businesses ... the biggest challenges people face today with medical costs ...
(Date:10/30/2014)... HealthDay Reporter , WEDNESDAY, Oct. 29, ... prostate cancer who also have certain heart problems may increase ... study suggests. , , The therapy in question is called androgen ... levels of male hormones to prevent the growth of cancer ... this hormone therapy was linked to triple the risk of ...
(Date:10/30/2014)... Dennis Thompson HealthDay Reporter ... in Liberia -- one of three West African nations ravaged ... officials said Wednesday. Dr. Bruce Aylward, WHO,s assistant director ... burials in Liberia and no increase in laboratory-confirmed cases. He ... tame the epidemic may be making some progress, The ...
(Date:10/30/2014)... IL (PRWEB) October 30, 2014 Dr. Joseph ... a new website for his practices; OB GYN in ... IL . This website contains important information about each ... as well as downloadable patient forms in English and Spanish. ... and the service pages on the website provide Dr. Furlin’s ...
(Date:10/30/2014)... Francisco, California (PRWEB) October 30, 2014 ... billion by 2020, according to a new study by ... coupled with surging demand for sugar and fat free ... to augment the demand for prebiotics over the forecast ... http://www.grandviewresearch.com/industry-analysis/prebiotics-market , Food & beverage was the ...
Breaking Medicine News(10 mins):Health News:Paramount Rx Discount Card Program Provides Valuable Resources in Midst of Current Health Care Reform 2Health News:Paramount Rx Discount Card Program Provides Valuable Resources in Midst of Current Health Care Reform 3Health News:Hormone Therapy May Up Heart-Related Deaths in Some Prostate Cancer Patients 2Health News:Hormone Therapy May Up Heart-Related Deaths in Some Prostate Cancer Patients 3Health News:Ebola Outbreak in Liberia May Be Slowing: WHO 2Health News:Ebola Outbreak in Liberia May Be Slowing: WHO 3Health News:Dr. Joseph Furlin Launches New Website with Information about Care Services 2Health News:Prebiotics Market Is Expected To Grow At A CAGR Of 9.3% From 2014 To 2020: Grand View Research, Inc. 2Health News:Prebiotics Market Is Expected To Grow At A CAGR Of 9.3% From 2014 To 2020: Grand View Research, Inc. 3Health News:Prebiotics Market Is Expected To Grow At A CAGR Of 9.3% From 2014 To 2020: Grand View Research, Inc. 4Health News:Prebiotics Market Is Expected To Grow At A CAGR Of 9.3% From 2014 To 2020: Grand View Research, Inc. 5
... that men who have undergone vasectomy may be at ... study was published in Cognitive and Behavioural Neurology. ... of this, 25 developed a dementia called primary progressive ... the chief scientist of this study Sandra Weintraub, this ...
... have multiple sclerosis (MS) for 10 years and have few of ... “benign MS” and that their symptoms will likely not ever occur ... study shows that unfortunately this may not be correct. ... of those whose MS was benign at 10 years, according to ...
... test that can distinguish between a pair of nearly ... treatment. ,Their report is published this week ... the National Academy of Sciences. ,"This simple ... quickly implemented in the clinic to benefit patients by ...
... appreciable decline in the number of women dying at childbirth ... Gautemala and Morocco that have managed to arrest this trend. ... of maternal deaths per 100,000 live births, was 301 in ... 70,000 women die every year in India but UNICEF says ...
... An anti-smoking campaign in Colorado that involves door-to-door ... of thousands of dollars and "is raising questions ... cessation efforts among minorities, the Denver Rocky Mountain ... approved a tobacco tax increase, which so far ...
... a national study, patients being treated for a ... Shore University Hospital// (NSUH) and Long Island Jewish ... arsenic compound, coupled with standard chemotherapy treatments, significantly ... newly-diagnosed acute promyelocytic leukemia, or APL, and participated ...
Cached Medicine News:Health News:A New Two-gene Test to Discern Similar Gastrointestinal Cancers 2Health News:India Lags Far Behind in Controlling Maternal Deaths 2Health News:Arsenic Compound Effective in Treating Rare Leukemia 2Health News:Arsenic Compound Effective in Treating Rare Leukemia 3
... to Z Drug Facts produced by ... on thousands of medications. It provides ... effect, drug interactions, patient information and ... reference for physicians, students, residents, pharmacists, ...
Very concise book answering the question: "I've got a diagnosis, which drugs do I use?". All 15 chapters written by highly skilled US specialists...
... with Integrated Calculators, based on Davis's Drug ... advance in drug reference. DDGNIC contains the ... Guide (9th Edition) and has integrated calculation ... product merges many of the advantages of ...
Allows health professionals to answer consumers' questions regarding safety issues concerning possible drug-herb and drug-food interactions....
Medicine Products: