Navigation Links
New Analyses Presented at ASCO Reaffirmed Efficacy and Safety of TORISEL in Patients With Advanced Kidney Cancer
Date:5/31/2008

sterolemia of grade 2 or higher, compared with interferon-alpha (P=0.001), but there was not a significant increase in hyperlipidemia versus interferon-alpha (P=0.675). However, the development of hyperglycemia or hypercholesterolemia did not have affect on overall survival or progression-free survival in this study.

The clinical data for TORISEL presented at the meeting represent only a portion of the totality of the safety and efficacy data from the ongoing clinical development of TORISEL.

About TORISEL

TORISEL is an mTOR inhibitor. Inhibition of mTOR in treated cancer cells blocked the translation of genes that regulate the cell cycle. In in vitro studies using renal cancer cell lines, TORISEL inhibited the activity of mTOR and resulted in reduced levels of certain cell growth factors involved in the development of new blood vessels, such as vascular endothelial growth factor.

TORISEL is approved for the treatment of advanced RCC in the United States, European Union and other markets, based on results of a phase 3 clinical study that demonstrated that TORISEL improves overall survival for patients with advanced RCC compared with interferon-alpha.

Important Safety Information

Hypersensitivity reactions manifested by symptoms, including, but not limited to anaphylaxis, dyspnea, flushing and chest pain have been observed with TORISEL.

Serum glucose, serum cholesterol and triglycerides should be tested before and during treatment with TORISEL.

The use of TORISEL is likely to result in hyperglycemia and hyperlipemia. This may result in the need for an increase in the dose of, or initiation of, insulin and/or oral hypoglycemic agent therapy and/or lipid-lowering agents, respectively.

The use of TORISEL may result in immunosuppression. Patients should be carefully observed for the occurrence of infections, including opportunistic infections.

Cases of interstitial lung disease, some resulting in death,
'/>"/>

SOURCE Wyeth Pharmaceuticals
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related medicine technology :

1. New MIRCERA(R) Data Analyses to be Featured at the American Society of Nephrology Annual Meeting
2. New Analyses of Long-Term LIALDA(TM) (mesalamine) Data Presented at ACG
3. Interim Response and Safety Analyses Support Continuation of Allos Therapeutics Pivotal Phase 2 PROPEL Trial of PDX in Patients with Peripheral T-Cell Lymphoma
4. Xeloda(R) XeNA Study Analyses of Xeloda, Docetaxel and Herceptin Combination Therapy for Metastatic Breast Cancer Featured at Major New Breast Cancer Symposium
5. Xeloda XeNA Study Analyses of Xeloda, Docetaxel and Herceptin Combination Therapy for Metastatic Breast Cancer Featured at Major New Breast Cancer Symposium
6. Four Analyses of Three-Year Clinical Data Suggest CYPHER(R) Sirolimus-Eluting Coronary Stent May Provide Alternative to Surgery for Patients with Multivessel Disease
7. Data To Be Presented at ASCO Supports Potential of Peregrines Cotara(R) for the Treatment of Brain Cancer
8. About 60 Clinical Studies Regarding Schering-Ploughs Oncology Compounds Will be Presented at ASCO
9. Two DOXIL(R) Studies to be Presented at American Society of Clinical Oncology (ASCO) Annual Meeting
10. Treprostinil Data Presented at American Thoracic Society Conference Demonstrates Significant Clinical Progress in All Four Routes of Administration
11. Safety and Efficacy Results Presented From Largest Prospective Controlled Clinical Study of Ulcerative Colitis
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/3/2015)... Spain , March 3, 2015  AT&T 1 ... PHIA) today announced that  AT&T  is the connectivity provider ... GoSafe was designed to help provide peace of mind ... them the freedom to live active lives with the ... they need it. The AT&T network 2 helps ...
(Date:3/3/2015)... March 3, 2015   VWR  (NASDAQ:  VWR), ... and solutions, announced today the expansion of its ... This agreement allows VWR increased access to NEB,s ... the U.S. and Puerto Rico.  In addition, customers ... VWR,s e-business platform, sales organization, and VWRCATALYST, our ...
(Date:3/3/2015)... , March 3, 2015  The eleventh annual Tucson ... of the world,s top research scientists, academics, oncologists and ... theories and learn about new outcomes in patient treatments ... Each year Ventana Medical Systems, Inc. ... sponsors the Tucson Symposium at the Hilton El Conquistador ...
Breaking Medicine Technology:AT&T Providing Connectivity for Philips GoSafe Mobile Medical Alert System, Empowering United States Seniors to be Connected to Emergency Care On-the-Go 2AT&T Providing Connectivity for Philips GoSafe Mobile Medical Alert System, Empowering United States Seniors to be Connected to Emergency Care On-the-Go 3AT&T Providing Connectivity for Philips GoSafe Mobile Medical Alert System, Empowering United States Seniors to be Connected to Emergency Care On-the-Go 4VWR Announces Expansion of Distribution Agreement with New England Biolabs 2Global scientific collaborators to explore latest pathology and oncology advancements at Tucson Symposium 2
... ClinStar, LLC , an established CRO providing clinical ... pharmaceutical and biotechnology industry, announced today that President and ... 6th Annual Clinical Research in Emerging Countries conference ... http://photos.prnewswire.com/prnh/20110719/SF36975LOGO ) The paradigm of traditional ...
... BOTHELL, Wash., July 21, 2011 Cardiac ... external defibrillators (AEDs) and diagnostic cardiac monitoring devices ... hospital information systems, announced today the new capability ... connectivity solution and the GE Healthcare Centricity® EMR ...
Cached Medicine Technology:ClinStar to Present on Conducting Clinical Trials in Russia 2Cardiac Science Expands Device Connectivity Solutions 2Cardiac Science Expands Device Connectivity Solutions 3
(Date:3/4/2015)... Georgia (PRWEB) March 04, 2015 The ... Sleep Awareness Week with World Sleep Awareness Day being ... awareness to the health and financial risks associated with ... support, the Sleep Apnea Treatment Centers of America have ... daily educational articles, they hope will virally inspire conversation ...
(Date:3/4/2015)... Durrie Vision, a Kansas ... in the region to offer two new intraocular lenses ... The implantable Tecnis® Multifocal lenses – now offered in ... a range of distances. Earlier this year the US ... two new IOLs – the Tecnis® Multifocal +2.75D and ...
(Date:3/4/2015)... March 04, 2015 Professionals with disabilities ... targeted outreach from companies, according to a new Think ... survey of 235 professionals with disabilities , respondents ... job search tools, including ones that are geared to ... Some highlights:, ,     Online job search tools ...
(Date:3/4/2015)... (PRWEB) March 04, 2015 Nurses, healthcare ... the American Cannabis Nurses Association (ACNA) to learn about ... a wide array of illnesses and conditions. The one-day ... Nursing,” is being offered on April 1 or April ... event was approved by the Ohio Nurses Association (OBN-001-91), ...
(Date:3/3/2015)... 2015 NOVAtime Technology, Inc. ( ... and Attendance / Workforce Management solutions, announced that ... SaaS Workforce Management / Time and Attendance ... , Since 2004, Innovative Services’ mission has ... the best quality of life. The company is ...
Breaking Medicine News(10 mins):Health News:Innovative Sleep Apnea Procedure Could Save US Healthcare System Billions 2Health News:Innovative Sleep Apnea Procedure Could Save US Healthcare System Billions 3Health News:Innovative Sleep Apnea Procedure Could Save US Healthcare System Billions 4Health News:Durrie Vision First in Region to Offer New Tecnis® Multifocus Lenses 2Health News:Job Seekers with Disabilities Seek Targeted Outreach from Employers and Online Job Search Tools, says New Think Beyond The Label Survey 2Health News:Job Seekers with Disabilities Seek Targeted Outreach from Employers and Online Job Search Tools, says New Think Beyond The Label Survey 3Health News:American Cannabis Nurses Association Announces Speaker Lineup for Educational Seminar in Cleveland 2Health News:American Cannabis Nurses Association Announces Speaker Lineup for Educational Seminar in Cleveland 3Health News:Innovative Services, Inc. Successfully Migrates to Cloud-Based NOVAtime Workforce Management Solution to Support Growth and Improve Payroll Processing Time 2Health News:Innovative Services, Inc. Successfully Migrates to Cloud-Based NOVAtime Workforce Management Solution to Support Growth and Improve Payroll Processing Time 3
... salt to reduce heart disease risk. The other side says ... people. Which is correct? There isn’t a simple answer. ... component of salt) in the diet lowers blood pressure. But ... her genes, age, and medical conditions, reports the November 2006 ...
... identified a naturally occurring enzyme that can break down ... Alzheimer's disease.// The finding may provide researchers with new ... of Alzheimer's patients and could one day help them ... of Medicine in St. Louis showed earlier this summer ...
... 2007 issue of the Pediatric Blood & Cancer investigates ... healthcare between industrialized and developing countries, as a way ... ,Pediatric oncology has witnessed path breaking strides in ... decades, but developing nations still have a long way ...
... the victims unintentionally demand, or actually have, sex while ... ,Research into this condition called sexsomania has been ... it. This disorder usually causes problems in relationships. It ... ,Several researchers believe sexsomania to be a variant of ...
... to researchers, a gene determines people’s sensitivity to pain.In ... pain could be prevented by blocking the expression of ... This could be a breakthrough in development of new ... a quarter of them had the genetic variant that ...
... of Singapore recently by researchers, reported in the American ... the tangible benefits of curries commonly used by Asian ... meals which are accompanied by a helping of curries ... is often indelibly associated with aging. Asian elders who ...
Cached Medicine News:Health News:Naturally Occurring Enzyme Can Break Down Key Part of Alzheimer's Plaques 2Health News:Videoconferencing, an impetus to Pediatric Oncology 2Health News:Gene determines pain threshold... 2Health News:Spices in curries spruce up aging minds 2
... the word "laboratory," it brings to mind images of ... familiar items. With the introduction of the Brady Code ... reader to the list of critical lab tools. Brady ... tool for the lab with the introduction of the ...
... stainless steel work surface. ... vibration to protect operator, ... vibration-producing equipment from the ... allows for multiple vibration-free ...
Round, height-adjustable, steel laboratory stools with small footprint for small spaces • Choose options like different height-adjustment mechanism or paint finish. • your choice of color...
... Chrome-plated metal frames ensure ... optimal cleanliness and chemical ... come with user-friendly pnuematic ... adjustment. Fixed footring standard. ...
Medicine Products: