Navigation Links
New Analyses Presented at ASCO Reaffirmed Efficacy and Safety of TORISEL in Patients With Advanced Kidney Cancer
Date:5/31/2008

- Data Showed Overall Survival Benefit With TORISEL Regardless of Nephrectomy Status; Additional Analysis Examined Specific Side Effects -

COLLEGEVILLE, Pa., May 31 /PRNewswire-FirstCall/ -- Wyeth Pharmaceuticals, a division of Wyeth (NYSE: WYE), today announced results of two new analyses of the pivotal study of the mTOR (mammalian target of rapamycin) inhibitor TORISEL(R) (temsirolimus), the only renal cancer therapy proven to extend median overall survival compared with interferon-alpha in patients with advanced renal cell carcinoma (RCC). These analyses, which are being presented at the 44th Annual Meeting of the American Society of Clinical Oncology (ASCO) in Chicago, reaffirm the efficacy and safety of TORISEL for the treatment of advanced RCC. TORISEL is the only approved cancer therapy that specifically inhibits the mTOR kinase, an important regulator of cell proliferation, cell growth and cell survival.

RCC will account for approximately 85 percent of renal cancers. There are an estimated 54,390 new cases of kidney and renal pelvis cancer diagnosed in the United States each year, and about 40 percent of patients have advanced disease at the time of diagnosis.

TORISEL was studied in a three-arm, phase 3 clinical trial of 626 patients with advanced RCC with three or more of six preselected prognostic risk factors who had received no prior systemic therapy. Results of this study demonstrated that TORISEL significantly increased median overall survival by 49 percent compared with interferon-alpha (10.9 months [95% CI: 8.6, 12.7] vs. 7.3 months [6.1, 8.8], P=0.0078) (Hazard Ratio [95% CI] = 0.73 [0.58, 0.92]).

"In summary, these analyses provide clinicians with additional information about the efficacy an
'/>"/>

SOURCE Wyeth Pharmaceuticals
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related medicine technology :

1. New MIRCERA(R) Data Analyses to be Featured at the American Society of Nephrology Annual Meeting
2. New Analyses of Long-Term LIALDA(TM) (mesalamine) Data Presented at ACG
3. Interim Response and Safety Analyses Support Continuation of Allos Therapeutics Pivotal Phase 2 PROPEL Trial of PDX in Patients with Peripheral T-Cell Lymphoma
4. Xeloda(R) XeNA Study Analyses of Xeloda, Docetaxel and Herceptin Combination Therapy for Metastatic Breast Cancer Featured at Major New Breast Cancer Symposium
5. Xeloda XeNA Study Analyses of Xeloda, Docetaxel and Herceptin Combination Therapy for Metastatic Breast Cancer Featured at Major New Breast Cancer Symposium
6. Four Analyses of Three-Year Clinical Data Suggest CYPHER(R) Sirolimus-Eluting Coronary Stent May Provide Alternative to Surgery for Patients with Multivessel Disease
7. Data To Be Presented at ASCO Supports Potential of Peregrines Cotara(R) for the Treatment of Brain Cancer
8. About 60 Clinical Studies Regarding Schering-Ploughs Oncology Compounds Will be Presented at ASCO
9. Two DOXIL(R) Studies to be Presented at American Society of Clinical Oncology (ASCO) Annual Meeting
10. Treprostinil Data Presented at American Thoracic Society Conference Demonstrates Significant Clinical Progress in All Four Routes of Administration
11. Safety and Efficacy Results Presented From Largest Prospective Controlled Clinical Study of Ulcerative Colitis
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/17/2015)... , April 17, 2015  Trovagene, Inc., (NASDAQ: ... today that clinical data presented at the 2015 ... urine-based Precision Cancer Monitoring ℠ (PCM) platform ... of EGFR T790M mutations in metastatic ... of EGFR T790M Mutation in Urinary Circulating Tumor ...
(Date:4/17/2015)... Research and Markets ( http://www.researchandmarkets.com/research/5hkm2f/medical_oxygen ) ... Systems - Global Strategic Business Report" report to ... markets for Medical Oxygen Systems in US$ Thousands by ... Cylinders & Regulators, and Oxygen Conserving Devices. The report ... Canada , Japan , ...
(Date:4/17/2015)... Today, the Pharmaceutical Research and Manufacturers ... biopharmaceutical companies as "We Work For Health Champions" ... community service. Established in 2009, the ... by the biopharmaceutical industry to honor employees who ... have also shown an outstanding commitment to their ...
Breaking Medicine Technology:Trovagene's Urinary ctDNA Assay Outperforms Tissue Biopsy in Clinical Study for the Detection of EGFR T790M Mutations in Metastatic Lung Cancer Patients 2Trovagene's Urinary ctDNA Assay Outperforms Tissue Biopsy in Clinical Study for the Detection of EGFR T790M Mutations in Metastatic Lung Cancer Patients 3Trovagene's Urinary ctDNA Assay Outperforms Tissue Biopsy in Clinical Study for the Detection of EGFR T790M Mutations in Metastatic Lung Cancer Patients 4Medical Oxygen Systems - 2015 Global Strategic Business Report Featuring Leading Players, Caire, Invacare & Philips Respironics 2PhRMA Applauds 2015 We Work For Health Champion Award Winners 2PhRMA Applauds 2015 We Work For Health Champion Award Winners 3
... MAP,Pharmaceuticals, Inc. (Nasdaq: MAPP ) announced ... of Unit Dose Budesonide (UDB) for the potential,treatment ... that the clinical,trial did not meet its co-primary ... in nighttime and daytime composite symptom scores, in,either ...
... 23 BN,ImmunoTherapeutics, Inc. today provided updated data ... MVA-BN(R)-HER2, in development as,therapy of metastatic breast cancer ... primary endpoint with regards to safety and by ... response was,detected in approximately 70% of evaluated patients. ...
Cached Medicine Technology:MAP Pharmaceuticals Announces Phase 3 Study of Unit Dose Budesonide in Children With Asthma Did Not Meet Primary Endpoints 2MAP Pharmaceuticals Announces Phase 3 Study of Unit Dose Budesonide in Children With Asthma Did Not Meet Primary Endpoints 3BN ImmunoTherapeutics Updates on Phase I/II Studies With Breast Cancer Vaccine 2BN ImmunoTherapeutics Updates on Phase I/II Studies With Breast Cancer Vaccine 3
(Date:4/17/2015)... Florida Hospital Wesley Chapel, Florida Hospital at ... were all selected as Top Workplaces in Tampa Bay. ... is ranked number one for large businesses according to ... in partnership with an independent research firm. Florida Hospital ... opened in October of 2012 with a vision of ...
(Date:4/17/2015)... (PRWEB) April 17, 2015 In Defense ... the following statement: “On Wednesday April 15th, the European ... adopted a resolution recognizing the Armenian Genocide, “paying tribute, ... of the one-and-a-half million innocent Armenian victims who perished ... (IDC) extols the EU for this timely and needed ...
(Date:4/17/2015)... Enthusiasts of gourmet cuisine and beverages will be ... The event will be held in the heart of downtown ... NW, Grand Rapids, MI 49503) and will feature wine personalities ... are encouraged to savor the food and beverage pairings while ... event will feature seven chefs, including:, ...
(Date:4/17/2015)... Most dental patients are not aware that ... overseas by foreign dental laboratories, according to the U.S. ... more than 40 states by their respective state boards ... Laboratories has created the “What’s In Your ... the consequences that could be associated with using poorly-made ...
(Date:4/17/2015)... Organic Valley, the nation’s largest cooperative ... International Year of Soils by “Cycling for Sustainability” through ... employees will travel 215 miles from Auburn, California, to ... about the impact of agriculture on water and soil ... Maine, Wisconsin, Oregon, and Washington state, the cyclists have ...
Breaking Medicine News(10 mins):Health News:Tampa Bay Times Selects Florida Hospital Wesley Chapel, Florida Hospital at Connerton Long Term Acute Care and Florida Hospital Carrollwood As Top Workplaces in Tampa Bay 2Health News:Tampa Bay Times Selects Florida Hospital Wesley Chapel, Florida Hospital at Connerton Long Term Acute Care and Florida Hospital Carrollwood As Top Workplaces in Tampa Bay 3Health News:Tampa Bay Times Selects Florida Hospital Wesley Chapel, Florida Hospital at Connerton Long Term Acute Care and Florida Hospital Carrollwood As Top Workplaces in Tampa Bay 4Health News:In Defense of Christians Condemns Armenian Genocide 2Health News:In Defense of Christians Condemns Armenian Genocide 3Health News:Children’s Leukemia Foundation of Michigan Presents 3rd Annual CRUSH Grand Rapids 2Health News:National Association Urges Transparency in Dental Industry 2Health News:Organic Valley Farmers and Employees "Cycling for Sustainability" Through 215 Miles of California Watershed April 19-25 2Health News:Organic Valley Farmers and Employees "Cycling for Sustainability" Through 215 Miles of California Watershed April 19-25 3
... Nigam, a top-notch Hindi singer, says that men are ... s managed to catch the attentions of many people. Sonu ... harassing him for sexual favors in return for publicity. ... now was employed against the girls in the industry. ...
... talked up the virtues of dog meat, saying the controversial ... heat . ,Dog soup, called dangogi-jang or boshintang ... season, the official Korean Central News Agency said, touting its ... an euphemism for dog meat that was coined by North ...
... UN experts, food safety is an issue for every country ... the almost 200 food safety incidents that occurred in the ... all countries to be vigilant when dealing with traders and ... examples, the Food and Agriculture Organization (FAO) and the World ...
... the University Clinic of the University of Navarra have ... adult stem cell growth for its capacity to ... ,Ana Fernandez Hortelano, ophthalmologist at the hospital, applied ... cornea in 70 rabbits for the purpose of regaining ...
... finasteride, a drug proven effective in preventing prostate cancer, just ... bedroom, can now put their fears to rest, thanks to ... the Southwest Oncology Group, found that though the drug does ... the course of time. ,As a part of ...
... antidepressants, and if so, should they be given ... by the National Institute for Health and Clinical ... bmj.com last month found that adding cognitive behaviour ... treatment is unlikely to improve outcomes for adolescents ...
Cached Medicine News:Health News:Male Casting Couch in Bollywood? 2Health News:Male Casting Couch in Bollywood? 3Health News:Gaps In Food Safety Systems Must Be Plugged :UN 2Health News:Mens Sexual Prowess Not Affected by Prostate Cancer Drug 2Health News:New Study Challenges NICE Guidelines on Adolescent Depression 2
As pupil size continues to play a significant role in the outcomes of refractive surgery, the pre-operative use of the Colvard Pupillometer continues to be the standard of care for obtaining accurate...
Subretinal Injection Cannula, Curved; 20g (0.90) x 1" (25mm); Tip Extension: 3mm, 32g (0.23); Angled at 35°....
Silicone Oil Cannula; 16g (1.40) x 8mm....
...
Medicine Products: