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New AVAC Report on Pre-Exposure Prophylaxis Calls for Immediate Planning to Anticipate Study Results of Potential New HIV Prevention Option
Date:8/3/2008

uman clinical research, PrEP is considered one of the promising clinical interventions against HIV currently in development," Warren continued. "By mid-2009, more people will be enrolling in PrEP studies than in both HIV vaccine and microbicide efficacy trials combined. Advocates and communities affected by HIV need to understand PrEP and its implications for the AIDS advocacy and global health agendas, and government and private funders committed to global health must step forward now to ensure that PrEP research is fully funded."

"We cannot wait for the study results to begin to prepare for the optimal use and delivery of PrEP," said Pedro Goicochea, an investigator of the iPrEx PrEP study currently underway in Peru and Ecuador "Instead, we should look ahead to consider all of the possible outcomes of these trials and make real plans for making PrEP available to those who can benefit from it, as quickly and safely as possible if it is proven effective."

Anticipating the Results of PrEP Trials provides an up-to-date status report on current PrEP research; addresses concerns about PrEP, including the possibilities of drug resistance, partial efficacy, and the potential for increased risk behavior and social stigma; looks at the potential impact of PrEP on future HIV prevention research; and considers what questions should we be preparing to ask now based on possible different research outcomes as PrEP studies begin reporting data in the next few years.

"This report provides an important overview of PrEP research and lays out the many difficult issues that are critical for advocates, communities and public health experts to understand as trials continue and report results," said Warren. "We cannot shy away from discussing issues such as potential drug resistance, the difficulty of adhering to a once-a-day pill regimen for people who are not sick, or the cost of providing PrEP. This report and today's meeting lay the groundwork for these important
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SOURCE AIDS Vaccine Advocacy Coalition
Copyright©2008 PR Newswire.
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