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New ALR-LRI Collaboration to Accelerate New Treatments for Lupus
Date:10/2/2013

NEW YORK, Oct. 2, 2013 /PRNewswire/ -- Today, the Alliance for Lupus Research (ALR) and the Lupus Research Institute (LRI) announced a trailblazing cooperative project to speed up the identification and availability of new treatments for lupus. Details of this new effort focused on identifying new treatments for lupus from among those that have been approved for other human conditions can be found at http://www.linkedin.com/in/lrxlstat.

With only one drug approved for lupus in over 50 years and serious side effects of existing treatments, there is a critical need for new therapies to treat and stop progression of this dangerous autoimmune disease. Despite the advance of new science, the overall pace of drug development in lupus has been slow. The ALR and LRI believe it is possible to identify therapies more quickly and are taking a proactive role to drive this process.

Developing New Lupus Treatments
An initial scan of all of the drugs and treatments available for human use has found approximately 70 existing therapies that have been approved for other conditions -- multiple sclerosis, rheumatoid arthritis, transplant rejection or cancer -- that potentially could be used to treat lupus. The new collaborative project will produce a comprehensive evidence-based analysis to fully document and prioritize each as a potential lupus therapy based on mechanism of action, safety profile, availability, feasibility to carry out a trial in lupus, and likelihood to succeed. A panel of academic and industry experts will review the database and prioritize potential therapies, and approximately 20 candidates are expected to emerge for further study in small focused science-rich clinical trials.

The study process and analysis will be fully transparent throughout; the priority list of candidate drugs and treatments will be made widely available for use across the lupus community
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SOURCE The Lupus Research Institute
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