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Neurostimulation Devices - Global Pipeline Analysis, Competitive Landscape and Market Forecasts to 2018
Date:7/10/2012

NEW YORK, July 10, 2012 /PRNewswire/ -- Reportlinker.com announces that a new market research report is available in its catalogue:

Neurostimulation Devices - Global Pipeline Analysis, Competitive Landscape and Market Forecasts to 2018

http://www.reportlinker.com/p0548454/Neurostimulation-Devices---Global-Pipeline-Analysis-Competitive-Landscape-and-Market-Forecasts-to-2018.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Pathology

Neurostimulation Devices - Global Pipeline Analysis, Competitive Landscape and Market Forecasts to 2018

Summary GlobalData's new report, "Neurostimulation Devices - Global Pipeline Analysis, Competitive Landscape and Market Forecasts to 2018" provides key data, information and analysis on the global neurostimulation devices market. It outlines the market landscape and provides comprehensive information on the key trends affecting the market, and key analytical content on the market dynamics. The report also reviews the competitive landscape and technology offerings.

This report is built using data and information sourced from proprietary databases, primary and secondary research and in-house analysis by GlobalData's team of industry experts.

Scope - Key geographies covered are the US, Canada, the UK, Germany, France, Italy, Spain, Japan, China, India, Australia, and Brazil.

- Key segments covered are spinal cord stimulators, deep brain stimulators, sacral nerve stimulators, vagus nerve stimulators and cortical stimulators.

- Annualized market revenues data from 2004 to 2011, forecast to 2018, and company share data for 2011.

- Qualitative analysis of key market trends, market drivers, and restraints by category within the neurostimulation devices market.

- Information on the leading market players, the competitive landscape, and the leading pipeline products and technologies.

- Key players covered include Medtronic, St. Jude Medical, Boston Scientific Corporation and Cyberonics.

Reasons to buy - Develop business strategies by understanding the trends and developments that are driving the neurostimulation devices market globally.

- Design and develop your product development, marketing and sales strategies.

- Develop market entry and market expansion strategies.

- Identify key players best positioned to take advantage of the emerging market opportunities.

- Exploit in-licensing and out-licensing opportunities by identifying the products most likely to ensure a robust return.

- What is the next big thing in the neurostimulation devices market landscape? Identify, understand and capitalize.

- Make more informed business decisions from the insightful and in-depth analysis of the global neurostimulation devices market and the factors shaping it.

1 Table of Contents

1 Table of Contents 4

1.1 List of Tables 7

1.2 List of Figures 9

2 Introduction 10

2.1 GlobalData Report Guidance 10

3 Disease Overview 11

3.1 Chronic Pain 11

3.1.1 Types of Chronic Pain Treated with Neurostimulation 11

3.1.2 Epidemiology 12

3.1.3 Treatment 12

3.2 Parkinson's Disease 13

3.2.1 Epidemiology 13

3.2.2 Treatment 14

3.3 Epilepsy 14

3.3.1 Epidemiology 14

3.3.2 Treatment 15

4 Reimbursement for Neurostimulation Devices 16

4.1 Spinal Cord Stimulators 16

4.2 Deep Brain Stimulators 16

4.3 Sacral Nerve Stimulators 17

4.4 Vagus Nerve Stimulators 17

4.5 Reimbursement for Neurostimulators Developed as Humanitarian Use Devices 17

4.6 Centers for Medicare and Medicaid Services Payment Changes, 2011 18

4.6.1 Ambulatory Surgical Center Payment System Rates, 2011 18

4.6.2 US Medicare Hospital Outpatient Payment Rates, 2011 19

5 Device Overview - Neurostimulation Devices 20

5.1 Market Segmentation 20

5.1.1 Spinal Cord Stimulators 20

5.1.2 Deep Brain Stimulators 20

5.1.3 Sacral Nerve Stimulators 20

5.1.4 Vagus Nerve Stimulators 21

5.1.5 Cortical Stimulators 21

6 Neurostimulation Devices Market - Global Market Characterization 22

6.1 Neurostimulation Devices Market, Global, Revenue ($m), Historic, 2004-2011 22

6.2 Neurostimulation Devices Market, Global, Revenue ($m), Forecast, 2011-2018 23

6.3 Neurostimulation Devices, Market Dynamics 24

6.3.1 Market Drivers 24

6.3.2 Market Restraints 29

7 Neurostimulation Devices Market, Revenue ($m), by Country, 2004-2018 30

7.1 Neurostimulation Devices Market, The US, Revenue ($m), Historic, 2004-2011 30

7.2 Neurostimulation Devices Market, The US, Revenue ($m), Forecast, 2011-2018 31

7.3 Neurostimulation Devices Market, Canada, Revenue ($m), Historic, 2004-2011 32

7.4 Neurostimulation Devices Market, Canada, Revenue ($m), Forecast, 2011-2018 33

7.5 Neurostimulation Devices Market, The UK, Revenue ($m), Historic, 2004-2011 34

7.6 Neurostimulation Devices Market, The UK, Revenue ($m), Forecast, 2011-2018 35

7.7 Neurostimulation Devices Market, Germany, Revenue ($m), Historic, 2004-2011 36

7.8 Neurostimulation Devices Market, Germany, Revenue ($m), Forecast, 2011-2018 37

7.9 Neurostimulation Devices Market, France, Revenue ($m), Historic, 2004-2011 38

7.10 Neurostimulation Devices Market, France, Revenue ($m), Forecast, 2011-2018 39

7.11 Neurostimulation Devices Market, Italy, Revenue ($m), Historic, 2004-2011 40

7.12 Neurostimulation Devices Market, Italy, Revenue ($m), Forecast, 2011-2018 41

7.13 Neurostimulation Devices Market, Spain, Revenue ($m), Historic, 2004-2011 42

7.14 Neurostimulation Devices Market, Spain, Revenue ($m), Forecast, 2011-2018 43

7.15 Neurostimulation Devices Market, Japan, Revenue ($m), Historic, 2004-2011 44

7.16 Neurostimulation Devices Market, Japan, Revenue ($m), Forecast, 2011-2018 45

7.17 Neurostimulation Devices Market, China, Revenue ($m), Historic, 2004-2011 46

7.18 Neurostimulation Devices Market, China, Revenue ($m), Forecast, 2011-2018 47

7.19 Neurostimulation Devices Market, India, Revenue ($m), Historic, 2004-2011 48

7.20 Neurostimulation Devices Market, India, Revenue ($m), Forecast, 2011-2018 49

7.21 Neurostimulation Devices Market, Australia, Revenue ($m), Historic, 2004-2011 50

7.22 Neurostimulation Devices Market, Australia, Revenue ($m), Forecast, 2011-2018 51

7.23 Neurostimulation Devices Market, Brazil, Revenue ($m), Historic, 2004-2011 52

7.24 Neurostimulation Devices Market, Brazil, Revenue ($m), Forecast, 2011-2018 53

8 Global Neurostimulation Devices Market - Strategic Competitive Assessment 54

8.1 Neurostimulation Devices Market, Global, Company Share (%), 2011 54

8.2 Medtronic 55

8.2.1 Overview 55

8.2.2 Medtronic, Key Marketed Products 57

8.3 St Jude Medical 61

8.3.1 Overview 61

8.3.2 St Jude Medical, Marketed Products 62

8.4 Boston Scientific 64

8.4.1 Overview 64

8.4.2 Boston Scientific, Marketed Products 64

8.5 Cyberonics 65

8.5.1 Overview 65

8.5.2 Cyberonics, Key Marketed Products 65

9 Neurostimulation Devices Market - Pipeline Assessment 67

9.1 Spinal Cord Stimulators, Pipeline Products 68

9.1.1 Algostim Device 68

9.1.2 Genesis Neurostimulation System 69

9.1.3 Nevro Senza System 69

9.1.4 Next Generation Spinal Cord Stimulator System 70

9.1.5 Precision Plus Spinal Cord Stimulation System 70

9.1.6 PrimeADVANCED - Heart Failure 71

9.1.7 Subcutaneous Array of Implantable Neural Transponder System 71

9.2 Deep Brain Stimulators, Pipeline Products 72

9.2.1 Activa PC - Refractory Epilepsy 73

9.2.2 Brio Neurostimulator 73

9.2.3 Coordinated Reset-Capable Implant 74

9.2.4 Deep Brain Stimulation - Alzheimer's Disease 74

9.2.5 Deep Brain Stimulation - Mild Cognitive Impairment 75

9.2.6 Deep Brain Stimulation System - Cachexia 75

9.2.7 Deep Brain Stimulation System - Obesity 76

9.2.8 Deep Brain Stimulation System - Post-Traumatic Stress Disorder 76

9.2.9 Deep Transcranial Magnetic Stimulation System - Alzheimer's Disease 77

9.2.10 Deep Transcranial Magnetic Stimulation System - Autism 77

9.2.11 Deep Transcranial Magnetic Stimulation System - Bipolar Disorder 78

9.3 Sacral Nerve Stimulators, Pipeline Products 78

9.3.1 Sacral Nerve Stimulation Device 78

9.3.2 SAINT System - Urinary Incontinence 79

9.3.3 Verv System - Overactive Bladder 79

9.4 Vagus Nerve Stimulators, Pipeline Products 80

9.4.1 Aspire New Parameters 80

9.4.2 CardioFit System 81

9.4.3 FitNes System - Alzheimer's Disease 81

9.4.4 NEMOS - Epilepsy 82

9.5 Cortical Stimulators, Pipeline Products 82

9.5.1 Cortistim 82

9.6 Other Neurostimulation Devices in the Pipeline 83

10 Neurostimulation Devices Market - Deals Landscape 84

10.1 Neurostimulation Devices Market: Mergers and Acquisitions 84

10.1.1 Sorin Group Invests $7m in Enopace Biomedical 84

10.1.2 Otto Bock Healthcare Acquires Remaining 44.4% Joint Venture Stake in Neurostream Technologies from Victhom Human Bionics 84

10.1.3 Boston Scientific Sells Neurovascular Business Unit to Stryker 85

10.1.4 Vycor Medical Completes Acquisition of NovaVision 85

10.2 Global Neurostimulation Devices Market, Venture Capital Deals 86

10.2.1 Functional Neuromodulation Raises Additional $3m in Venture Financing 87

10.2.2 Nervomatrix Secures $3.5m in Series A Venture Financing 87

10.2.3 Cortec Secures $3.2m in Seed Financing 87

10.2.4 ImThera Medical Secures $4m in Series C Venture Financing 88

10.2.5 Phagenesis Secures $9.3m in Series B Venture Financing 88

10.2.6 Autonomic Technologies Secures $32m in Series C Venture Financing 88

10.2.7 SPR Therapeutics Secures $0.25m in Financing Round 88

10.2.8 Nexstim Secures Additional $2.8m in Venture Financing Round 89

10.2.9 BlueWind Medical Secures Seed Financing 89

10.2.10 Synapse Biomedical Secures $0.43m in Financing Round 89

10.2.11 EBS Technologies Secures $4.4m in Second Round of Financing 89

10.3 Global Neurostimulation Devices Market, Partnership Deals 90

10.3.1 GE Healthcare Enters into a Distribution Agreement with KC BioMedix 90

10.3.2 EndoStim Enters into an Agreement with Arizona State University 90

10.3.3 Ardiem Medical Enters into Licensing Agreement with Case Western Reserve University 91

11 Appendix 92

11.1 Definitions 92

11.1.1 Neurostimulation Devices 92

11.2 Acronyms 93

11.3 Sources 94

11.4 Research Methodology 97

11.4.1 Secondary Research 97

11.4.2 Primary Research 98

11.4.3 Models 98

11.4.4 Forecasts 98

11.4.5 Expert Panels 98

11.5 GlobalData Consulting 99

11.6 Contact Us 99

11.7 Disclaimer 99

List of Tables Table 1: Ambulatory Surgical Center Medicare Payment for Spinal Cord Stimulation, 2010 vs. 2011 18

Table 2: Ambulatory Surgical Center Medicare Payment for Deep Brain Stimulation, 2010 vs. 2011 18

Table 3: Ambulatory Surgical Center Medicare Payment for Sacral Nerve Stimulation, 2010 vs. 2011 18

Table 4: Medicare Hospital Outpatient Payment for Spinal Cord Stimulation, 2010 vs. 2011 19

Table 5: Medicare Hospital Outpatient Payment for Sacral Nerve Stimulation, 2010 vs. 2011 19

Table 6: Medicare Hospital Outpatient Payment for Deep Brain Stimulation, 2010 vs. 2011 19

Table 7: Neurostimulation Devices Market, Global, Revenue ($m), 2004-2011 22

Table 8: Neurostimulation Devices Market, Global, Revenue ($m), 2011-2018 23

Table 9: Healthcare Costs vs. Health-related Quality of Life with Spinal Cord Stimulation and Conventional Medical Management 24

Table 10: Incremental Cost-effectiveness of Spinal Cord Stimulation Compared with Conventional Medical Management 25

Table 11: Cost Effectiveness, Post-vagus Nerve Stimulation Therapy vs. Pre-vagus Nerve Stimulation Therapy 26

Table 12: Example of Neurostimulation Products* through FDA's Fast-track Program 26

Table 13: Example of Neurostimulation Products* through FDA's Humanitarian Device Exemption Program 27

Table 14: Pipeline Products In Development for New Indications 27

Table 15: Neurostimulation Devices Market, The US, Revenue ($m), 2004-2011 30

Table 16: Neurostimulation Devices Market, The US, Revenue ($m), 2011-2018 31

Table 17: Neurostimulation Devices Market, Canada, Revenue ($m), 2004-2011 32

Table 18: Neurostimulation Devices Market, Canada, Revenue ($m), 2011-2018 33

Table 19: Neurostimulation Devices Market, The UK, Revenue ($m), 2004-2011 34

Table 20: Neurostimulation Devices Market, The UK, Revenue ($m), 2011-2018 35

Table 21: Neurostimulation Devices Market, Germany, Revenue ($m), 2004-2011 36

Table 22: Neurostimulation Devices Market, Germany, Revenue ($m), 2011-2018 37

Table 23: Neurostimulation Devices Market, France, Revenue ($m), 2004-2011 38

Table 24: Neurostimulation Devices Market, France, Revenue ($m), 2011-2018 39

Table 25: Neurostimulation Devices Market, Italy, Revenue ($m), 2004-2011 40

Table 26: Neurostimulation Devices Market, Italy, Revenue ($m), 2011-2018 41

Table 27: Neurostimulation Devices Market, Spain, Revenue ($m), 2004-2011 42

Table 28: Neurostimulation Devices Market, Spain, Revenue ($m), 2011-2018 43

Table 29: Neurostimulation Devices Market, Japan, Revenue ($m), 2004-2011 44

Table 30: Neurostimulation Devices Market, Japan, Revenue ($m), 2011-2018 45

Table 31: Neurostimulation Devices Market, China, Revenue ($m), 2004-2011 46

Table 32: Neurostimulation Devices Market, China, Revenue ($m), 2011-2018 47

Table 33: Neurostimulation Devices Market, India, Revenue ($m), 2004-2011 48

Table 34: Neurostimulation Devices Market, India, Revenue ($m), 2011-2018 49

Table 35: Neurostimulation Devices Market, Australia, Revenue ($m), 2004-2011 50

Table 36: Neurostimulation Devices Market, Australia, Revenue ($m), 2011-2018 51

Table 37: Neurostimulation Devices Market, Brazil, Revenue ($m), 2004-2011 52

Table 38: Neurostimulation Devices Market, Brazil, Revenue ($m), 2011-2018 53

Table 39: Neurostimulation Devices Market, Global, Company Revenue ($m), 2011 54

Table 40: Medtronic, Key Marketed Products*, Neurostimulation Devices 57

Table 41: Activa RC, PC and SC Series Neurostimulator, Features and Benefits 58

Table 42: Kinetra Neurostimulator, Features and Benefits 58

Table 43: Soletra Neurostimulator, Features and Benefits 58

Table 44: Restore Series Neurostimulator, Features and Benefits 59

Table 45: PrimeAdvanced Neurostimulator, Features and Benefits 59

Table 46: Itrel 3 neurostimulator, Features and Benefits 59

Table 47: External Trialing System, Features and Benefits 60

Table 48: St Jude Medical, Key Marketed Products*, Neurostimulation Devices 62

Table 49: Libra Family of Primary Cell IPGs, Features and Benefits 62

Table 50: Eon C Primary Cell IPGs, Features and Benefits 63

Table 51: Genesis Primary Cell IPG, Features and Benefits 63

Table 52: Rechargeable IPGs, Features and Benefits 63

Table 53: Boston Scientific, Key Marketed Products*, Neurostimulation Devices 64

Table 54: Precision Plus Spinal Cord Stimulation System, Features and Benefits 64

Table 55: Cyberonics, Key Marketed Products*, Neurostimulation Devices 65

Table 56: VNS Therapy Generator, Features and Benefits 66

Table 57: Spinal Cord Stimulators, Pipeline Products 68

Table 58: Algostim Device, Product Status 68

Table 59: Genesis Neurostimulation System - Chronic Angina, Product Status 69

Table 60: Nevro Senza System, Product Status 69

Table 61: Next Generation Spinal Cord Stimulator System, Product Status 70

Table 62: Precision Plus Spinal Cord Stimulation System, Product Status 70

Table 63: PrimeAdvanced - Heart Failure, Product Status 71

Table 64: Subcutaneous Array of Implantable Neural Transponder System - Chronic Pain, Product Status 71

Table 65: Deep Brain Stimulators, Pipeline Products 72

Table 66: Activa PC - Refractory Epilepsy, Product Status 73

Table 67: Brio Neurostimulator, Product Status 73

Table 68: CR-Capable Implant, Product Status 74

Table 69: Deep Brain Stimulation - Alzheimer's Disease, Product Status 74

Table 70: Deep Brain Stimulation - Mild Cognitive Impairment, Product Status 75

Table 71: Deep Brain Stimulation - Cachexia, Product Status 75

Table 72: Deep Brain Stimulation - Obesity, Product Status 76

Table 73: Deep Brain Stimulation - Post-Traumatic Stress Disorder 76

Table 74: Deep TMS System - Alzheimer's Disease, Product Status 77

Table 75: Deep Transcranial Magnetic Stimulation System - Autism, Product Status 77

Table 76: Deep Transcranial Magnetic Stimulation System - Bipolar Disorder, Product Status 78

Table 77: Sacral Nerve Stimulators, Pipeline Products 78

Table 78: Sacral Nerve Stimulation Device, Product Status 78

Table 79: SAINT System - Urinary Incontinence, Product Status 79

Table 80: Verv System - Overactive Bladder, Product Status 79

Table 81: Vagus Nerve Stimulators, Pipeline Products 80

Table 82: Aspire NP, Product Status 80

Table 83: CardioFit System, Product Status 81

Table 84: FitNes System - Alzheimer's Disease, Product Status 81

Table 85: NEMOS - Epilepsy, Product Status 82

Table 86: Cortical Stimulators, Pipeline Products 82

Table 87: Cortistim, Product Status 82

Table 88: Other Neurostimulation Devices in the Pipeline 83

Table 89: Neurostimulation Devices Market, Mergers and Acquisitions, Global, 2010-2011 84

Table 90: Global Neurostimulation Devices Market, Venture Capital Deals 86

Table 91: Global Neurostimulation Devices Market, Partnership Deals 90

List of Figures Figure 1: Neurostimulation Devices, Market Segmentation 20

Figure 2: Neurostimulation Devices Market, Global, Revenue ($m), 2004-2011 22

Figure 3: Neurostimulation Devices Market, Global, Revenue ($m), 2011-2018 23

Figure 4: Neurostimulation Devices, Regulatory Path for Pipeline Products, 2012 28

Figure 5: Neurostimulation Devices Market, The US, Revenue ($m), 2004-2011 30

Figure 6: Neurostimulation Devices Market, The US, Revenue ($m), 2011-2018 31

Figure 7: Neurostimulation Devices Market, Canada, Revenue ($m), 2004-2011 32

Figure 8: Neurostimulation Devices Market, Canada, Revenue ($m), 2011-2018 33

Figure 9: Neurostimulation Devices Market, The UK, Revenue ($m), 2004-2011 34

Figure 10: Neurostimulation Devices Market, The UK, Revenue ($m), 2011-2018 35

Figure 11: Neurostimulation Devices Market, Germany, Revenue ($m), 2004-2011 36

Figure 12: Neurostimulation Devices Market, Germany, Revenue ($m), 2011-2018 37

Figure 13: Neurostimulation Devices Market, France, Revenue ($m), 2004-2011 38

Figure 14: Neurostimulation Devices Market, France, Revenue ($m), 2011-2018 39

Figure 15: Neurostimulation Devices Market, Italy, Revenue ($m), 2004-2011 40

Figure 16: Neurostimulation Devices Market, Italy, Revenue ($m), 2011-2018 41

Figure 17: Neurostimulation Devices Market, Spain, Revenue ($m), 2004-2011 42

Figure 18: Neurostimulation Devices Market, Spain, Revenue ($m), 2011-2018 43

Figure 19: Neurostimulation Devices Market, Japan, Revenue ($m), 2004-2011 44

Figure 20: Neurostimulation Devices Market, Japan, Revenue ($m), 2011-2018 45

Figure 21: Neurostimulation Devices Market, China, Revenue ($m), 2004-2011 46

Figure 22: Neurostimulation Devices Market, China, Revenue ($m), 2011-2018 47

Figure 23: Neurostimulation Devices Market, India, Revenue ($m), 2004-2011 48

Figure 24: Neurostimulation Devices Market, India, Revenue ($m), 2011-2018 49

Figure 25: Neurostimulation Devices Market, Australia, Revenue ($m), 2004-2011 50

Figure 26: Neurostimulation Devices Market, Australia, Revenue ($m), 2011-2018 51

Figure 27: Neurostimulation Devices Market, Brazil, Revenue ($m), 2004-2011 52

Figure 28: Neurostimulation Devices Market, Brazil, Revenue ($m), 2011-2018 53

Figure 29: Neurostimulation Devices Market, Global, Company Share* (%), 2011 54

Figure 30: Global Neurostimulation Devices, Product Mapping 55

Figure 31: Neurostimulation Devices, Analysis of Pipeline Products by Clinical Stage of Development 67

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