Navigation Links
NeurogesX Doses First Patient in Phase 2 Clinical Study of NGX-1998 Liquid Capsaicin Formulation
Date:11/2/2010

SAN MATEO, Calif., Nov. 2, 2010 /PRNewswire-FirstCall/ -- NeurogesX, Inc. (Nasdaq: NGSX), a biopharmaceutical company focused on developing and commercializing novel pain management therapies, today announced dosing of the first patient in its Phase 2 clinical study of NGX-1998, a liquid formulation of high-concentration capsaicin, in patients with postherpetic neuralgia (PHN).

The target profile for NGX-1998 is to provide safety, efficacy and tolerability that is at least comparable to Qutenza® (capsaicin) 8% patch with a significantly shorter application time.

The Phase 2, adaptive-design, clinical study will be conducted in two stages. The first stage is designed to determine the shortest tolerable anesthetic pretreatment regimen. The second stage will evaluate two NGX-1998 dose concentrations using the pretreatment regimens determined during stage 1. The objective is to select the appropriate concentration of NGX-1998 and pretreatment period for further evaluation in a Phase 3 clinical program. Up to 200 PHN patients are targeted for enrollment.

Jeffrey Tobias, MD Executive Vice President for Research and Development and Chief Medical Officer commented, "We are very pleased to have initiated our Phase 2 study of NGX-1998. Previous Phase 1 studies have suggested that NGX-1998 may deliver an effective dose of capsaicin in as little as five minutes. This study will now explore the shortest tolerable pretreatment regimen as well as provide preliminary efficacy and safety data of two concentrations of NGX-1998 in patients with PHN. These data will help us select the optimal dose of NGX-1998 and shortest overall treatment regimen. NGX-1998 is an important product candidate for the long-term growth of our neuropathic pain franchise and we are happy to have this clinical trial underway."

About NeurogesX, Inc.NeurogesX, Inc. (Nasdaq:

SOURCE NeurogesX
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. NeurogesX to Hold Conference Call to Discuss Third Quarter 2010 Results
2. NeurogesX to Present at Oppenheimer & Co Healthcare Conference
3. Although NeurogesX/Astellass Qutenza is Only Approved for Postherpetic Neuralgia, Surveyed U.S. Physicians are Likely to Prescribe It for All Neuropathic Pain Types
4. NeurogesX Appoints Seasoned Sales and Marketing Executive as New Board Director
5. NeurogesX Receives FDA Approval of Qutenza(TM) (capsaicin) 8% Patch for Treatment of Postherpetic Neuralgia (PHN)
6. NeurogesX Expands Commercial Operations Leadership Team
7. NeurogesX to Hold Conference Call to Discuss Third Quarter 2009 Financial Results
8. NeurogesX to Present at JMP Securities Healthcare Focus Conference
9. NeurogesX Announces Preliminary Results of FDA-Requested Qutenza(TM) Study
10. NeurogesX Receives FDA Orphan Drug Designation for Qutenza(TM) for Treatment of Postherpetic Neuralgia
11. NeurogesX Announces Publication of Phase 3 Data for QUTENZA(TM) (NGX-4010) in Postherpetic Neuralgia (PHN) by The Lancet Neurology
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/10/2014)... July 10, 2014   Ventana Medical Systems, Inc. ... it has entered into an agreement with Merck KGaA, ... EMD Serono in the United States ... with Merck KGaA,s biopharmaceutical division on the development and ... target using Ventana,s proprietary diagnostic assays. In alignment with ...
(Date:7/10/2014)... , July 10, 2014 Decision Resources ... awareness of the U.S. Food and Drug Administration,s (FDA) ... phosphate binder Velphoro, which was approved by the FDA ... chronic kidney disease (CKD) patients on dialysis. ... TreatmentTrends: Nephrology (US) Q2 2014 : ...
(Date:1/15/2014)... Jan. 15, 2014  Research and Markets ( http://www.researchandmarkets.com/research/6k27gw/dental ) ... Market - Global Industry Analysis, Size, Share, Growth, Trends ... offering. (Logo: http://photos.prnewswire.com/prnh/20130307/600769 ... used on patients in order to treat dental impairments, ...
Breaking Medicine Technology:Ventana Medical Systems, Inc. and Merck KGaA, Darmstadt, Germany to develop companion diagnostic test for cancer treatment 2Ventana Medical Systems, Inc. and Merck KGaA, Darmstadt, Germany to develop companion diagnostic test for cancer treatment 3Half of Surveyed Nephrologists Report Moderate Familiarity with Velphoro, Which Received FDA Approval Late Last Year for the Treatment of Hyperphosphatemia in Dialysis 2Half of Surveyed Nephrologists Report Moderate Familiarity with Velphoro, Which Received FDA Approval Late Last Year for the Treatment of Hyperphosphatemia in Dialysis 3Dental Consumables Market - Global Industry Analysis, Size, Share, Growth, Trends And Forecast, 2013 - 2018 2Dental Consumables Market - Global Industry Analysis, Size, Share, Growth, Trends And Forecast, 2013 - 2018 3
... N.Y. , July 6 E. Fougera & ... first generic approval from the FDA for Adapalene Cream 0.1% ... to Differin® by Galderma Pharmaceuticals. According to industry data, U.S. ... $55 million . This approval also marks the fourth product ...
... PARSIPPANY, N.J. , July 6 July 5th is ... in the state of Wisconsin and every year almost 7,200 of them ... an added incentive to quit with the Wisconsin smoke free law that ... , , ...
Cached Medicine Technology:Fougera® Announces First Generic Approval of Adapalene Cream 0.1% (Rx), Equivalent to Differin® 2Fougera® Announces First Generic Approval of Adapalene Cream 0.1% (Rx), Equivalent to Differin® 3Wisconsin Statewide Smoke-Free Law May Prompt Smokers to Quit 2Wisconsin Statewide Smoke-Free Law May Prompt Smokers to Quit 3
(Date:7/14/2014)... EurekaMag.com has newly published results of ... contagious liver disease that ranges in severity from ... serious, lifelong illness that attacks the liver. An estimated ... Hepatitis C virus infection of which approximately 80% of ... category covers all studies on Hepatitis C , the ...
(Date:7/14/2014)... "Medical devices, tests, and treatments are critical ... is a star when it comes to innovations in ... working on amazing products and ideas that are our ... to Dale Kaye CEO of the Innovation Tri-Valley ... brilliant minds and businesses that are leading society into ...
(Date:7/14/2014)... WI (PRWEB) July 14, 2014 Doctor ... announced the launch of their new company website. The ... valuable free information on chiropractic marketing. It's also a ... that Inception has to offer. , When contacted at ... the newest version of our main website. Our site ...
(Date:7/14/2014)... Essex, CT (PRWEB) July 14, 2014 Summer ... means vacations, camping, days at the beach, swimming and other ... want everyone to be safe, happy and healthy all summer ... of a list of the three must-have custom imprinted products ... first summer essential is of course sunblock. Sunscreen ...
(Date:7/13/2014)... 2014 Save the Date for the 2014 ... Jacksonville, FL , BOXWOODS & BowTies “A Modern Twist on ... The Women’s Board of Wolfson Children’s Hospital will ... to continue their ongoing commitment to raising funds for the ... , What: The 2014 Art & Antiques Show is a ...
Breaking Medicine News(10 mins):Health News:EurekaMag.com Publishes 64,900 New Studies on Hepatitis C 2Health News:Believing in the Possible – Innovation Tri-Valley’s Sixth Innovation Forum Examines the Tri-Valley’s Wealth of Innovators 2Health News:Believing in the Possible – Innovation Tri-Valley’s Sixth Innovation Forum Examines the Tri-Valley’s Wealth of Innovators 3Health News:Believing in the Possible – Innovation Tri-Valley’s Sixth Innovation Forum Examines the Tri-Valley’s Wealth of Innovators 4Health News:Doctor Mike Hamilton From Inception Chiropractic Websites Announces the Launch of Their New Website 2Health News:Why These Three Summer Essentials from 4AllPromos Can Improve Summer 2Health News:Save the Date for the 2014 Art & Antiques Show benefiting Wolfson Children's Hospital in Jacksonville, FL 2Health News:Save the Date for the 2014 Art & Antiques Show benefiting Wolfson Children's Hospital in Jacksonville, FL 3Health News:Save the Date for the 2014 Art & Antiques Show benefiting Wolfson Children's Hospital in Jacksonville, FL 4Health News:Save the Date for the 2014 Art & Antiques Show benefiting Wolfson Children's Hospital in Jacksonville, FL 5Health News:Save the Date for the 2014 Art & Antiques Show benefiting Wolfson Children's Hospital in Jacksonville, FL 6Health News:Save the Date for the 2014 Art & Antiques Show benefiting Wolfson Children's Hospital in Jacksonville, FL 7Health News:Save the Date for the 2014 Art & Antiques Show benefiting Wolfson Children's Hospital in Jacksonville, FL 8Health News:Save the Date for the 2014 Art & Antiques Show benefiting Wolfson Children's Hospital in Jacksonville, FL 9
... 21 LUMEDX Corporation, a leading,provider of ... introduces software to manage data and track ... Module empowers clinicians,by making critical clinical information ... For more information -- including a free ...
... May 20 The U.S. Department of,Health and ... advertising,campaign focusing on the quality of care available ... HHS, Centers for Medicare & Medicaid Services (CMS),in ... newspapers, promote Hospital,Compare ( http://www.hospitalcompare.hhs.gov ), an easy-to-use ...
... researchers,found that the frequency with which critically-ill patients ... a,multidisciplinary medical center such as Mayo Clinic compared ... the National Healthcare Safety,Network (NHSN). This is good ... are generally strong across the U.S. in intensive ...
... 2008) A newly published study presents data ... (COPD), including emphysema and chronic bronchitis, experienced markedly ... a combination of nebulized formoterol fumarate inhalation solution ... treatment with tiotropium alone. The two medications, ...
... BEDFORD, Mass., May 20 Hologic, Inc. (Nasdaq:,HOLX) today ... at the NASDAQ 21st Investor Program being held May ... parties are invited to listen to a live audio ... at 10:45 a.m.,BST on the investor section of the ...
... One of 35,000 Doctors Now Using E-Prescribing, ... (PCMA) is unveiling a new print ad campaign ... successfully use electronic,prescribing (e-prescribing) technology and who also ... new ad features Dr. R. David Allard, a ...
Cached Medicine News:Health News:New Anticoagulation Management Software Helps Clinics Enhance Efficiency and Improve Patient Safety 2Health News:National Ad Campaign Highlights Patient Ratings For More Than 1,000 Local U.S. Hospitals 2Health News:National Ad Campaign Highlights Patient Ratings For More Than 1,000 Local U.S. Hospitals 3Health News:Mayo Clinic Research Shows U.S. Intensive Care Units' Prevention of Pneumonia in Critically-ill Patients Generally Strong; Identifies Area of Improvement 2Health News:Mayo Clinic Research Shows U.S. Intensive Care Units' Prevention of Pneumonia in Critically-ill Patients Generally Strong; Identifies Area of Improvement 3Health News:Concomitant treatment with nebulized formoterol fumarate & tio-significant improvements -- COPD 2Health News:Concomitant treatment with nebulized formoterol fumarate & tio-significant improvements -- COPD 3Health News:Concomitant treatment with nebulized formoterol fumarate & tio-significant improvements -- COPD 4Health News:PCMA's New Ad Campaign: E-Prescribing is Ready Now 2
... precision, ergonomics, and value!, Comfortable ... soft non-slip, contoured handle , Finer ... plunger spring action , Completely autoclavable ... the need for recalibration , Easy-to-read ...
10L...
... is ideal for repeated pipetting ... volume FInnpipettes offer the same ... Finnpipette Digital pipettes: New, ... Soft-touch tip ejection, Safety label, ...
... The Eppendorf Reference Series 2000 Pipette is ... stroke, a compact and robust design, and ... is used to operate the measuring stroke ... tip. Product features:Eppendorf "pipette/tip" system ensures utmost ...
Medicine Products: