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NeurogesX Announces Preliminary Results from Second Phase 3 Clinical Trial in HIV-DSP
Date:2/27/2008

y of the conference call will be available beginning February 27, 2008 at 7:00 p.m. EST (4:00 p.m. PST) and ending on March 12, 2008. The replay telephone number is 1-877-660-6853 (USA) or 1-201-612-7415 (International), Account Number: 3055, Conference ID Number: 276693.

A live web cast of the call will also be available from the Investor Relations section on the Company's web site at http://www.neurogesx.com. A web cast replay can be accessed on the Company's web site beginning February 27, 2008, at approximately 7:00 p.m. EST. The replay will remain available until March 27, 2008.

About NGX-4010

NGX-4010 is a non-narcotic, locally-acting analgesic formulated in a dermal patch containing capsaicin, a selective TRPV1 agonist. Capsaicin is released from the patch and absorbed into the skin without significant absorption into the bloodstream. Accordingly, users of NGX-4010 may be able to avoid the systemic side effects of anti-convulsants, anti-depressants and opioids, including sedation and the potential for abuse and addiction associated with some of these drugs. NGX-4010 is administered in a physician's office in a non-invasive process that involves pre-treating the painful area with a topical anesthetic followed by the application of the patch. NGX-4010 has been shown to reduce pain for up to 12 weeks in certain neuropathic pain conditions.

About PHN and HIV-DSP

PHN is a painful condition affecting sensory nerve fibers. It is a complication of shingles, a second outbreak of the varicella-zoster virus, which initially causes chickenpox. Following an initial infection, some of the virus can remain dormant in nerve cells. Years later, age, illness, stress, medications or other factors that are not well understood can lead to reactivation of the virus. The rash and blisters associated with shingles usually heal within six weeks, but some people continue to experience pain for year
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SOURCE NeurogesX, Inc.
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