Navigation Links
Neurocrine Biosciences Announces the Start of Phase IIb Study of Elagolix in Uterine Fibroids
Date:3/27/2013

SAN DIEGO, March 27, 2013 /PRNewswire/ -- Neurocrine Biosciences, Inc. (NASDAQ: NBIX) today announced that a Phase IIb clinical trial to evaluate elagolix for the treatment of uterine fibroids has been initiated. Elagolix is an oral gonadotropin-releasing hormone (GnRH) antagonist, in development by AbbVie for the treatment of uterine fibroids and endometriosis. Neurocrine and AbbVie entered into a collaboration and license agreement for elagolix during 2010.

"Based on the positive data from the uterine fibroids Phase IIa trial, AbbVie has progressed elagolix into Phase IIb for uterine fibroids," said Kevin C. Gorman , President and Chief Executive Officer of Neurocrine Biosciences. "We are pleased with this advancement, as well as the ongoing Phase III program in endometriosis, and look forward to the continued development of elagolix in these two disease states which both have high unmet medical needs."

The Phase IIb uterine fibroids study is a randomized, parallel, double-blind, placebo-controlled clinical trial evaluating elagolix in women with heavy uterine bleeding associated with uterine fibroids. This study will evaluate 280 subjects over a six-month placebo-controlled dosing period. The primary efficacy endpoint of the study is an assessment of the change in menstrual blood loss utilizing the alkaline hematin method comparing baseline to month six. Additional secondary efficacy endpoints will be evaluated including assessing the change in fibroid volume and hemoglobin. Bone mineral density will be assessed via DXA scan at baseline, the conclusion of dosing, and six months post-dosing.

About Uterine Fibroids

Uterine fibroids are benign hormonally responsive tumors that form in the wall of the utervus. They are the most common type of abnormal growth found in a woman's pelvis and are mos
'/>"/>

SOURCE Neurocrine Biosciences, Inc.
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. Neurocrine Biosciences Announces Conference Call and Webcast to Present First Quarter 2012 Financial Results
2. Neurocrine Biosciences Reports First Quarter 2012 Results
3. Neurocrine Biosciences to Present at the Jefferies 2012 Global Healthcare Conference
4. Neurocrine Biosciences Announces Conference Call And Webcast To Present Second Quarter 2012 Financial Results
5. Neurocrine Biosciences To Present At The Morgan Stanley Global Healthcare Conference
6. Neurocrine Biosciences Announces Conference Call and Webcast to Present Third Quarter 2012 Financial Results
7. Neurocrine Biosciences To Present At Lazard Capitalmarkets 9th Annual Healthcare Conference
8. Neurocrine Biosciences To Present At Deutsche Banks 2012 dbAccess BioFEST
9. Neurocrine Biosciences Announces Additional European And United States Patents Issued On Proprietary VMAT2 Inhibitor
10. Neurocrine Biosciences Announces Conference Call And Webcast To Present Fourth Quarter And Year-End 2012 Financial Results
11. Neurocrine Biosciences To Present At The Leerink Swann Global Healthcare Conference 2013
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/15/2014)... , Jan. 15, 2014 AARP Foundation today ... to support older adults suffering from the severe cold ... and its members are committed to helping those in ... and AARP Foundation will match dollar-for-dollar contributions up to ... The matching program will be administered through AARP Foundation. ...
(Date:1/15/2014)... 15, 2014 Shire plc (LSE: SHP, ... the Office of Fair Trading (OFT) approval condition to the ... ViroPharma Incorporated (NASDAQ: VPHM).   As a result ... OFT approval, and Shire expects to complete the tender offer ... subject to the satisfaction of all of the remaining conditions ...
(Date:1/15/2014)...  In an unprecedented effort to curb the spread of ... and other transport vehicles, an advanced and portable UV germicidal ... personnel for the first time. In order ... contact with these deadly pathogens, West Palm Beach ... to begin sanitizing the interior surfaces of its ambulance fleet ...
Breaking Medicine Technology:AARP Foundation Establishes Winter Relief Fund for Older Adults Suffering from the Severe Cold Weather 2AARP Foundation Establishes Winter Relief Fund for Older Adults Suffering from the Severe Cold Weather 3Shire Waives OFT Condition Relating to the Acquisition of ViroPharma Inc. 2Shire Waives OFT Condition Relating to the Acquisition of ViroPharma Inc. 3Superbugs No Longer Ride In Rescue Vehicles 2
(Date:4/14/2014)... treat children with uncomplicated acute appendicitis is a reasonable ... fewer missed school days, according to a pilot study. ... Hospital and published online April 12 in the ... the first prospective study on nonoperative management of acute ... , Researchers enrolled 77 patients age 7 to 17 ...
(Date:4/14/2014)... 2014, Perth, Australia. Drug discovery company Proteomics International ... of a companion diagnostic (CDx) test with the ... The research team authenticated the panel of biomarkers ... samples. Seven biomarkers were validated at high stringency ... The mass spectrometry data was then cross-validated using ...
(Date:4/14/2014)... 2014) When it comes to the cost and ... Patients get the best care when they are treated ... extensive experience in their current job, according to a ... and Columbia Business School. The study was published in ... Applied Economics . , The review of more ...
(Date:4/13/2014)... STANFORD, Calif. A low-cost empowerment program for ... and sexual harassment of these girls, who live ... and are frequently attacked, a large new study ... Stanford University School of Medicine, Lucile Packard Children,s ... No Worldwide, validated the program,s effectiveness in combating ...
(Date:4/11/2014)... the processes that control brain cell production could pave ... brain-related disorders. , Scientists have gained new understanding of ... how and when nerve and brain cells are formed ... and keeps it healthy. Their findings could help explain ... which is a fundamental characteristic of many diseases including ...
Breaking Medicine News(10 mins):Health News:Antibiotics alone are a successful treatment for uncomplicated acute appendicitis in kids 2Health News:Antibiotics alone are a successful treatment for uncomplicated acute appendicitis in kids 3Health News:Longer nurse tenure on hospital units leads to higher quality care 2Health News:Empowerment program greatly decreases incidence of rape, Stanford/Packard-led study finds 2Health News:Empowerment program greatly decreases incidence of rape, Stanford/Packard-led study finds 3Health News:Empowerment program greatly decreases incidence of rape, Stanford/Packard-led study finds 4
... , , , ... the Cure((R)), the world,s largest grassroots network of breast cancer survivors and ... Diego Affiliate will receive proceeds from the album release concert of Billboard-charting ... Supper Club, will feature Miz Mandy along with more than 20 band ...
... , SANTA CLARA, Calif., July 21 ... on the a lawsuit brought by Ormco Corporation (Ormco) against Align Technology, ... California (District Court), which was tried by jury June 9 through June ... previously disclosed, on June 26, 2009, the jury delivered a verdict against ...
... , ANDOVER, Mass., July 21 ... that serves the Texas Midwest area, finished its implementation of ... for advanced authentication. Following its enterprise roll-out of Sentillion,s ... Go to enable caregivers in its trauma center to use ...
... , SAVANNAH, Ga. July 21 Senator ... Chief Medical Officer of the Coastal Health District, Charles Powell, ... Coastal Area Agency on Aging, gathered today to urge all ... for diabetes. Together, they launched the Medicare Diabetes Screening ...
... strategies from the U.S. Surgeons General provided roadmap to take decisive ... , , AUSTIN, Texas and TUCSON, ... the Lance Armstrong Foundation (LAF), cancer survivor, and champion cyclist, battles ... National Call to Action on Cancer Prevention and Survivorship that ...
... putting their health at risk by avoiding disease screening, ... masculinity. Because they prove their masculinity through their sexuality ... goes against their notion of masculinity. Waverly Duck, a ... Yale University in the US, argues that current leading ...
Cached Medicine News:Health News:Susan G. Komen for the Cure(R), San Diego to Receive Proceeds from Miz Mandy Album Release Concert 2Health News:Susan G. Komen for the Cure(R), San Diego to Receive Proceeds from Miz Mandy Album Release Concert 3Health News:Align Technology Provides Update on Patent Litigation with Ormco Corporation 2Health News:Align Technology Provides Update on Patent Litigation with Ormco Corporation 3Health News:Align Technology Provides Update on Patent Litigation with Ormco Corporation 4Health News:Hendrick Health System Deploys Sentillion's Tap & Go Advanced Authentication Solution 2Health News:Hendrick Health System Deploys Sentillion's Tap & Go Advanced Authentication Solution 3Health News:Savannah City Leaders Launch Medicare Diabetes Screening Project 2Health News:Savannah City Leaders Launch Medicare Diabetes Screening Project 3Health News:First Anniversary of New War on Cancer Marks Many Advances 2Health News:First Anniversary of New War on Cancer Marks Many Advances 3Health News:First Anniversary of New War on Cancer Marks Many Advances 4Health News:First Anniversary of New War on Cancer Marks Many Advances 5Health News:First Anniversary of New War on Cancer Marks Many Advances 6Health News:First Anniversary of New War on Cancer Marks Many Advances 7Health News:'Go to the doctor? Only if I'm really sick...' 2
... TC-PLUS Solution tricompartmental total knee prosthesis stems ... arthroplasty. State-of-the-art design and manufacturing technologies have ... biomechanical function as well as a favorable ... insert to keep wear to a minimum. ...
... The TC-PLUS Solution tricompartmental total knee prosthesis ... knee arthroplasty. State-of-the-art design and manufacturing technologies ... optimum biomechanical function as well as a ... tibial insert to keep wear to a ...
... Knee System is a long term, quality ... Available in both posterior stabilized and anatomically ... System provides the flexibility needed to address ... ease of identification keeps the user in ...
... a long term, quality solution based on ... posterior stabilized and anatomically correct cruciate retaining ... flexibility needed to address patients' needs. In ... keeps the user in mind and promotes ...
Medicine Products: