Navigation Links
Neurobiological Technologies Announces Viprinex(TM) Does Not Pass Interim Futility Analysis
Date:12/17/2008

EMERYVILLE, Calif., Dec. 17 /PRNewswire-FirstCall/ -- Neurobiological Technologies, Inc. (NTI(R)) (Nasdaq: NTII) today announced that an independent Data Safety Monitoring Board (DSMB) has determined that the current clinical trials of Viprinex(TM) for the treatment of acute ischemic stroke are unlikely to show benefit. As a result, the company has terminated further enrollment in the trials. NTI will obtain and analyze the data before evaluating the potential for any future development of Viprinex. The interim analysis conducted by the DSMB evaluated stroke patients' outcome 90 days following an acute ischemic stroke, comparing treatment with Viprinex to treatment with placebo. The DSMB determined that there was no clinically meaningful difference in outcome between the two treatment groups as measured on the modified Rankin scale of disability, the primary endpoint of the study.

"We are deeply disappointed that Viprinex did not improve overall patient outcomes in our clinical study," said Paul E. Freiman, president and chief executive officer. "This news is a significant set-back for our clinical program. Once we obtain the data and we have analyzed the results from this study, which we expect to occur in early 2009, we will determine whether we will pursue any further development of Viprinex. In the meantime, we are implementing plans we have developed to reduce our expenses, which will likely result in a significant reduction in our overall headcount if we determine that future development of Viprinex is not warranted."

About Neurobiological Technologies, Inc.

Neurobiological Technologies, Inc., (Nasdaq: NTII) is a biopharmaceutical company focused on developing novel, first-in-class agents for central nervous system conditions and other serious unmet medical needs. The Company's most advanced product candidate, Viprinex(TM) (ancrod), has been studied in Phase 3 clinical trials for evaluation as a new drug to treat acute ischemic stroke; the future development of Viprinex is under consideration. NTI also has early- stage development programs for Alzheimer's and Huntington's diseases and rights to receive payments on an approved drug for Alzheimer's disease and an investigational drug in Phase 3 trials for brain swelling.


'/>"/>
SOURCE Neurobiological Technologies, Inc.
Copyright©2008 PR Newswire.
All rights reserved

Related medicine technology :

1. Neurobiological Technologies Announces FDA Agreement to Consolidate Viprinex Phase 3 Trials Accelerating Time to Pivotal Data
2. Neurobiological Technologies Reaches Patient Enrollment Target For Interim Analysis of Viprinex(TM) Phase 3 Stroke Trials
3. Neurobiological Technologies, Inc. Presents Dosing Rationale for Viprinex(TM) (ancrod) at the European Stroke Conference
4. Fifth DSMB Meeting Supports Neurobiological Technologies Continuation of Phase 3 Stroke Trials With Viprinex(TM) (ancrod)
5. Neurobiological Technologies, Inc. and Buck Institute Partner to Develop Novel Treatment for Alzheimers Disease
6. InteRNA Technologies and VU University Medical Center to Develop microRNA-Based Diagnostics and Therapeutics for Cancer
7. Athera Biotechnologies and Dyax Announce a Collaboration to Discover and Develop Antibodies for Cardiovascular Inflammation
8. ImmunoVaccine Technologies DepoVax(TM) Shows Positive Results for Cancer and Infectious Diseases
9. Wound Management Technologies, Inc. Announces Conference Plans in Boston and Additional Clinical Research on CellerateRx(R)
10. Experts Assert That Varian Technologies Deliver Speed and Clinical Accuracy in Treating Cancer Patients
11. Palatin Technologies Presents PL-3994 Clinical Trial Results at the 12th Annual Scientific Meeting of the Heart Failure Association of America
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/12/2016)... 12, 2016  Innophos Holdings, Inc. (NASDAQ: IPHS ), ... today announced that it will host a live conference call ... discuss its fourth quarter and full year 2015 results. ... release detailing fourth quarter and full year results will be ... --> --> The conference ...
(Date:2/12/2016)... -- SI-BONE, Inc., a medical device company that pioneered the use of ... (MIS) device indicated for fusion for certain disorders of the sacroiliac ... Administrative Contractor (MAC) covering the states of Connecticut ... Massachusetts , Minnesota , ... Rhode Island , Vermont ...
(Date:2/12/2016)... 2016 On Thursday, Feb. 11, 2016, surgeons ... David,s North Austin Medical Center successfully completed the first ... ® Surgical System with Trumpf Medical,s advanced operating ... Lakshman , M.D., colorectal surgeon at the Texas Institute ... Table Motion technology, which seamlessly combines the da Vinci ...
Breaking Medicine Technology:
(Date:2/12/2016)... ... 12, 2016 , ... Young Asset Protection, a full service ... the latest charity campaign in their community enrichment program. Art Expression utilizes after-school ... cause are currently being accepted at: http://artexpressioninc.org/ . , Art Expression is ...
(Date:2/12/2016)... ... February 12, 2016 , ... J Thomas ... by continuing it’s commitment to act as Agents of Change in the community, ... with area homeless families to fulfill immediate needs and help them move into ...
(Date:2/12/2016)... Pa. (PRWEB) , ... February 12, 2016 , ... ... sort through a world of exterior design possibilities. CertainTeed, North America’s leading brand ... tools by expanding the product offerings showcased in the mobile version of the ...
(Date:2/12/2016)... ... February 12, 2016 , ... The Central Coast Autism Spectrum Center (CCASC) invites teens ages 11-18 ... night of fun for teens with and without special needs to gather in a safe ... the event. The dance will take place on Saturday, Feb. 13 from 7 to 9:30 ...
(Date:2/12/2016)... CA (PRWEB) , ... February 12, 2016 , ... ... Film Studios. The new cartoon style themes are great for showcasing pictures, videos as ... customized scene generators, titles like introductions, lower thirds, transitions and a beautiful frame overlay. ...
Breaking Medicine News(10 mins):