Navigation Links
Neuralstem Receives FDA Approval to Dose Patients in Cervical Region in Ongoing ALS Trial
Date:10/24/2011

ctors concluded, "We have successfully treated 12 ALS patients with unilateral or bilateral intraspinal injections of neural stem cells. All of the patients tolerated the procedure without major surgical complications, and there are no indications to date that the stem cells themselves are either toxic or injurious to the spinal cord. Our quantitative clinical assessments showed no evidence of acceleration of disease following stem cell injections, meeting our stated goal of proving safety for this Phase I trial. We have cautious optimism that a few of the patients may have slowed in their progression of lower extremity weakness, and one patient may have improved."

Prolongation of life for patients with ALS will require therapeutic intervention at the level of the cervical spinal motor neurons affecting respiratory function," they continued. "To reach this ultimate goal we plan to move to injections into the cervical spinal cord,  which is the next stage of this Phase I trial."

"We are very excited about the trial results to date and encouraged by the safety data," commented Lucie Bruijn, PhD, Chief Scientist, The ALS Association. "This is a very important step forward for stem cell therapy in ALS and we are fortunate to have such a committed and skilled research team at Emory and Neuralstem to move this forward. These results pave the way for the next stage of the trial and for future stem cell transplants in ALS."

"This is a major milestone for Neuralstem," said Richard Garr, Neuralstem CEO and President. "Demonstrating the feasibility and safety of transplanting our cells in the upper regions of the spinal cord will have important ramifications for our spinal cord injury program as well as ALS."

About the Trial

The Phase I trial to assess the safety of Neuralstem's spinal cord neural stem cells and intraspinal transplantation method in ALS patients has been underway since January 2010. The trial is designed to enroll up t
'/>"/>

SOURCE Neuralstem, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Dr. Eva Feldman, Principal Investigator, Presents Interim Data on Neuralstem ALS Trial
2. Neuralstem Announces Notice of Allowance for Two Additional Neurogenic Compound Patents
3. Neuralstem Updates NSI-189 Major Depression Trial
4. Dr. Eva Feldman, Principal Investigator, Presents Interim Safety Results for Neuralstem ALS Trial
5. Neuralstem Updates ALS Clinical Trial Progress
6. Neuralstem Receives FDA Orphan Designation for Spinal Cord Stem Cells for Treatment of ALS
7. Neuralstem Receives FDA Approval to Commence Drug Trial for Major Depression
8. Neuralstems Human Stem Cells Integrate into Nervous System of Rats with Animal Model of ALS
9. Neuralstems ALS Trial on Clinical Hold
10. Neuralstem Licenses Cleveland Clinic Spinal Cord Injection Technology
11. Neuralstem Announces Issuance of Core Technology Patent in Europe
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/21/2015)... , April 21, 2015 Cardiologists at Henry ... of stroke in patients with an irregular heartbeat. ... procedure, Henry Ford is able to add another ... atrial fibrillation, which affects the heart,s ability to pump. ... and first-ever commercial Watchman implant at a non-clinical ...
(Date:4/21/2015)... 21, 2015  Celebrating a major anniversary and ... same time is fitting for Enova Illumination. In ... surgical headlights, LED technology was a new concept ... been at the forefront of LED surgical headlight ... lightest and most dependable LED surgical headlights available. ...
(Date:4/21/2015)... , April 21, 2015 Workers, compensation ... 5.4 percent decrease in utilization helped offset a 7 ... new data released today by Express Scripts (NASDAQ: ... Workers, Compensation Drug Trend Report discusses the overall pharmacy ... among injured workers. Opioid Management Mitigates ...
Breaking Medicine Technology:Stroke Risk Caused by Abnormal Heart Rhythm Reduced Without Blood Thinners 2Stroke Risk Caused by Abnormal Heart Rhythm Reduced Without Blood Thinners 3Enova Illumination Celebrates 10th Anniversary at Cutting Edge of LED Surgical Headlight Innovation; Introduces Newest and Brightest LED Surgical Headlight in the World 2Enova Illumination Celebrates 10th Anniversary at Cutting Edge of LED Surgical Headlight Innovation; Introduces Newest and Brightest LED Surgical Headlight in the World 3Workers' Compensation Prescription Drug Spend Increased 1.9 Percent in 2014, Stabilized by Effective Utilization Management Programs 2Workers' Compensation Prescription Drug Spend Increased 1.9 Percent in 2014, Stabilized by Effective Utilization Management Programs 3Workers' Compensation Prescription Drug Spend Increased 1.9 Percent in 2014, Stabilized by Effective Utilization Management Programs 4
... WAYNE, N.J., June 6, 2011 Bayer HealthCare Pharmaceuticals ... AL pharadin in SYM ptomatic P rostate ... chloride, which is exclusively licensed from Algeta ASA, in ... met its primary endpoint by significantly improving overall survival. ...
... June 5, 2011 Nektar Therapeutics (Nasdaq: ... of patients in a Phase 2 clinical study evaluating ... total of 33 women in the study with prior ... for response rate using either RECIST 1.0 criteria (response ...
Cached Medicine Technology:Bayer's Investigational Compound Radium-223 Chloride Met its Primary Endpoint of Significantly Improving Overall Survival in a Phase III Trial in Patients with Castration-Resistant Prostate Cancer That Has Spread to the Bone 2Bayer's Investigational Compound Radium-223 Chloride Met its Primary Endpoint of Significantly Improving Overall Survival in a Phase III Trial in Patients with Castration-Resistant Prostate Cancer That Has Spread to the Bone 3NKTR-102 Shows High Response Rate and Sustained Duration of Response in Women with Platinum-Resistant/Refractory Ovarian Cancer Previously Treated with Doxil® 2NKTR-102 Shows High Response Rate and Sustained Duration of Response in Women with Platinum-Resistant/Refractory Ovarian Cancer Previously Treated with Doxil® 3NKTR-102 Shows High Response Rate and Sustained Duration of Response in Women with Platinum-Resistant/Refractory Ovarian Cancer Previously Treated with Doxil® 4NKTR-102 Shows High Response Rate and Sustained Duration of Response in Women with Platinum-Resistant/Refractory Ovarian Cancer Previously Treated with Doxil® 5NKTR-102 Shows High Response Rate and Sustained Duration of Response in Women with Platinum-Resistant/Refractory Ovarian Cancer Previously Treated with Doxil® 6NKTR-102 Shows High Response Rate and Sustained Duration of Response in Women with Platinum-Resistant/Refractory Ovarian Cancer Previously Treated with Doxil® 7NKTR-102 Shows High Response Rate and Sustained Duration of Response in Women with Platinum-Resistant/Refractory Ovarian Cancer Previously Treated with Doxil® 8
(Date:4/21/2015)... Angelo’s FabriClean has recently announced that ... clients that avail the area rug cleaning services. Area ... with hi-tech equipments, making use of the quick drying ... natural, high pressure steam extraction to clean even the ... area rugs made with delicate fabric. , “Good ...
(Date:4/21/2015)... April 21, 2015 Catalent (Booth ... technologies and development solutions for drugs, biologics and ... ADVASEPT™ Lock, a stopper-less, glass- and needle-free vial ... medications. Easily opened, ADVASEPT Lock attaches to a ... container closure with the security of an advanced ...
(Date:4/21/2015)... QuickMedical, a veteran-owned leader in ... represents Schiller America's line of Ambulatory ... and Vital Signs Monitors, among many other items. ... global leader in the development and production of ... close cooperation with the world's leading physicians and ...
(Date:4/21/2015)... (PRWEB) April 21, 2015 The ... Citrate Industry is a professional and in-depth study ... Sodium Citrate Market with a focus on ... in the sodium citrate market research are Cargill, ... Natural Biological, Cofco Biochemical, Capchem, Lianyungang Mupro Fi, ...
(Date:4/21/2015)... April 21, 2015 Further strengthening ties ... $1.2 million in donated goods and services to the ... through the USF Health BRIDGE Healthcare Clinic. , The ... clinic in its eighth year – provides primary medical ... one night a week inside the USF Health Morsani ...
Breaking Medicine News(10 mins):Health News:Angelo’s FabriClean Now Offers Area Rug Cleaning in South Surrey with Complimentary Pick-Up and Delivery 2Health News:Catalent Announces the Expansion of its Advanced, Aseptic, Glass-Free Injectable Platform with New ADVASEPT™ Lock Delivery Technology 2Health News:QuickMedical Launches New Product Line: Schiller America 2Health News:QuickMedical Launches New Product Line: Schiller America 3Health News:Sodium Citrate Industry Global Key Manufacturers Analysis Report 2015-2020 2Health News:Sodium Citrate Industry Global Key Manufacturers Analysis Report 2015-2020 3Health News:USF Health and Florida Hospital Tampa Partner to Expand BRIDGE Clinic 2Health News:USF Health and Florida Hospital Tampa Partner to Expand BRIDGE Clinic 3
... 24, 2011David Satcher, MD, PhD, former U.S. Surgeon General, describes ... and adult health that we are facing today," calling for ... in the June issue of Childhood Obesity , a ... is available online. A long-time advocate in the ...
... , FRIDAY, June 24 (HealthDay News) -- Drinking even ... concentrations enough to increase the chances of being seriously injured ... get behind the wheel, a new study suggests. Researchers ... a blood-alcohol concentration of just 0.01 percent -- much lower ...
... June 24, 2011 A new anti-inflammatory drug used by ... a year-long study involving researchers from UT Southwestern Medical Center. ... Journal of Medicine , mark the first time a drug ... type 2 diabetes and chronic kidney disease. Previous studies have ...
... Researchers from Boston University,s Slone Epidemiology Center have found ... (MHC) that confer a higher risk of systemic lupus ... currently appears on-line in Human Genetics , is ... association between genetic variants in the MHC region and ...
... , THURSDAY, June 23 (HealthDay News) -- After suffering a ... and fears about the future are less depressed and live ... In fact, 48 percent of the people who participated in ... were not depressed a year later, compared to 37.7 of ...
... (HealthDay News) -- New research suggests that the adverse effects ... latest findings, from a University of Rhode Island study that ... revealed that preemies grow up to be less healthy, struggle ... compared to those born full-term. One reason for this, ...
Cached Medicine News:Health News:Even One Glass of Beer, Wine Boosts Car Crash Risk: Study 2Health News:Drug shows improved kidney function for type 2 diabetics, UT Southwestern researchers report 2Health News:New genetic risk factors of lupus found in study of African-American women 2Health News:Early Talk Therapy May Help Stroke Patients Bounce Back 2Health News:Early Talk Therapy May Help Stroke Patients Bounce Back 3Health News:Effects of Premature Birth May Stretch Into Adulthood: Study 2
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
Medicine Products: