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NephRx Corp. Awarded New U.S. Patent for Oral Mucositis Agent NX002
Date:3/23/2011

which protects NX002 and related compounds, have been exclusively licensed to NephRx by the University of Chicago.

NX002 may also have applications in acute and chronic diseases of the gastrointestinal tract, such as Crohn's disease and ulcerative colitis.  It has been shown to stimulate the growth of epithelial cells and to promote mucosal wound healing after injury. 

About Oral MucositisMucositis is an inflammation and ulceration of the lining of the mouth, throat or gastrointestinal tract associated with cancer chemotherapy and radiation therapy.  The pain resulting from mucositis can be so severe that it is cited by patients as a major reason for discontinuing cancer treatment.  In severe cases, mucositis prevents eating and often results in hospitalization.  Mucositis afflicts approximately 15-40% of patients receiving standard-dose chemotherapy and 76-100% of patients receiving chemotherapy for bone marrow transplant.  It affects virtually all patients receiving radiation therapy for head and neck and gastrointestinal cancers.  In total, an estimated 400,000 patients are affected by mucositis each year in the U.S. alone, and the incidence is rising as use of radiation and chemotherapy increases. About NephRxNephRx Corporation is a clinical-stage biotechnology company dedicated to the discovery and development of therapeutic products for the treatment of acute kidney failure and other renal disorders, and diseases of the gastrointestinal tract, including mucositis, Crohn's disease and ulcerative colitis.  NX001 is currently in Phase I testing and will be developed initially for the treatment of delayed graft function in kidney transplant patients.  NX002 is in preclinical development as a treatment for oral mucositis, a common, painful and dose-limiting side effect of cancer chemotherapy and radiation therapy.  For more information, visit http://www.ne
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SOURCE NephRx Corporation
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