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NeoStem Provides Results for 2010 and an Update on Recent Activities
Date:4/1/2011

los' T-reg therapy represents a novel approach for restoring immune balance by enhancing T-reg cell number and function.  Through exclusive licenses, Athelos has secured the rights to a broad patent estate within the T-reg cell field. Some of the earlier projects on the Athelos development agenda include investigating the clinical feasibility of T-reg-based therapeutics to prevent and treat graft-versus-host disease and solid organ rejection, as well as a broad class of other autoimmune diseases.  Results from ongoing Phase I trials of T-reg cell therapy for autoimmune disorders will determine the next phase of trials. Another company developed by PCT which is pursuing a cell-based therapy for cardiovascular diseases, specifically acute myocardial infarction (AMI), is called Amorcyte Therapeutics. Amorcyte has completed a Phase I trial with its lead product, AMR-001. This is an autologous bone marrow-derived, CD34+ cell line selected to treat damaged heart muscle following AMI. According to Amorcyte, this is the first stem cell trial to show dose-related "significant" improvements in limiting perfusion following AMI. PCT has a small ownership interest in Amorcyte today (less than 1%) but is integral to Amorcyte in its role as a contract manufacturer of the therapeutic (the cells, their delivery and the regulatory process).  A Phase 2a clinical trial is expected in 2011 and PCT has secured the manufacturing contract.  

NeoStem expects the year ahead to continue to be one of positive transformation and growth for the Company in its mission to capture the emerging paradigm shift to cell based medicine.

About NeoStem, Inc.NeoStem, Inc. is an international biopharmaceutical company with adult stem cell operations in the U.S., a network of adult stem cell therapeutic providers in China as well as a 51% ownership interest in a profitable Chinese generic pharmaceutical manufacturing company.  NeoStem is focused on accelerating the
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