Nektar Therapeutics to Present Positive Data at Upcoming Medical and Scientifi... ( SAN FRANCISCO April 10 /- Nektar ...)

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Nektar Therapeutics to Present Positive Data at Upcoming Medical and Scientific Meetings

Date:4/10/2008

SAN FRANCISCO, April 10 /PRNewswire-FirstCall/ -- Nektar Therapeutics (Nasdaq: NKTR) announced today that positive preclinical and clinical results for its pipeline programs will be presented at numerous medical and scientific meetings over the coming months. These presentations will highlight Nektar's novel therapeutic candidates in the areas of oncology, anti-infectives and central nervous system (CNS), which leverage Nektar's innovative small molecule PEGylation and liquid aerosol platforms.

The data presentations are as follows:

-- April 12-16, 2008: Presentation of Positive Preclinical Data for NKTR-102 (PEG-irinotecan) at the American Association for Cancer Research (AACR) Annual Meeting in San Diego, California:

Poster #766: "Enhanced anti-tumor activity of NKTR-102, a novel

PEGylated-irinotecan, when administered in combination with

bevacizumab in a mouse model of human colorectal tumors"

Poster #5741: "NKTR-102, a novel PEGylated-irinotecan, has an

enhanced pharmacokinetic profile with reduced gastrointestinal and

hematopoietic toxicity compared to irinotecan with repeat dosing"

Poster #5742: "NKTR-102, a novel PEGylated-irinotecan, has a

superior acute safety, tolerability, and pharmacokinetic profile

compared to irinotecan"

-- May 8-10, 2008: Presentation of Phase 1 Clinical Trial Multi-Dose Safety Data for NKTR-118 (oral PEG-naloxol) in Opioid Bowel Dysfunction at the American Pain Society (APS) Meeting in Tampa, Florida:

Poster #210: "Results from a phase I, double-blind, randomized,

placebo-controlled, multiple-dose study evaluating the safety,

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SOURCE Nektar Therapeutics
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