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Nektar Commences Phase 2 Trial of NKTR-118 (oral PEG-naloxol) Evaluating Efficacy and Safety as Treatment for Opioid-Induced Bowel Dysfunction
Date:1/8/2008

and application of the company's technology platforms, and statements regarding the progress, potential, and future clinical plans for NKTR-118. These forward-looking statements involve risks and uncertainties, including but not limited to: (i) the company's proprietary product candidates, including NKTR- 118, are in the early phases of clinical development and the risk of failure is high and can unexpectedly occur at any stage, (ii) the timing or success of the commencement or conclusion of planned clinical trials is subject to a number of uncertainties including but not limited to clinical design, patient enrollment, regulatory requirements and clinical outcomes, (iii) the company's success in meeting minimum clinical end points and obtaining regulatory approvals for product candidates, such as NKTR-118 (iv) the company's patent applications for its proprietary product candidates may not issue, patents that have issued may not be enforceable or sufficient to protect against competitive products, or intellectual property licenses from third parties may be required in the future, (v) the outcome of any future intellectual property or other litigation related to the company's proprietary product candidates, such as NKTR-118 and (vi) potential competition from existing approved products (branded, generic or over-the-counter) or product candidates under development by other companies could negatively impact the commercial potential of the company's product candidates due to such competitive factors as efficacy and safety profiles, pricing, and reimbursement by third party payers. Other important risks and uncertainties are detailed in the company's reports and other filings with the Securities and Exchange Commission (SEC), including its most recent Quarterly Report on Form 10-Q filed with the SEC on November 9, 2007. Actual results could differ materially from the forward- looking statements contained in this press release. The company undertakes no obligation to upd
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